Testing Data
(Image: Detection of TREK 1 in human brain membrane lysate.)
anti-Human TREK 1 Antibody | anti-TREK 1 antibody
TREK 1, Polyclonal Antibody, Rabbit
Testing Data
(Image: Detection of TREK 1 in human brain membrane lysate.)
Testing Data
(Image: Detection of TREK 1 in human brain membrane lysate.)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes one of the members of the two-pore-domain background potassium channel protein family. This type of potassium channel is formed by two homodimers that create a channel that leaks potassium out of the cell to control resting membrane potential. The channel can be opened, however, by certain anesthetics, membrane stretching, intracellular acidosis, and heat. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Uniprot Description
TREK-1: Outward rectifying potassium channel. Homodimer (Potential). Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Channel, potassium; Membrane protein, integral; Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: 1q41
Cellular Component: voltage-gated potassium channel complex; endoplasmic reticulum membrane; endoplasmic reticulum; plasma membrane
Molecular Function: potassium ion leak channel activity; outward rectifier potassium channel activity; potassium channel inhibitor activity
Biological Process: synaptic transmission; G-protein coupled receptor protein signaling pathway; regulation of membrane potential
Research Articles on TREK 1
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Product Notes
The TREK 1 kcnk2 (Catalog #AAA555159) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The TREK 1, Polyclonal Antibody, Rabbit reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's TREK 1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the TREK 1 kcnk2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TREK 1, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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