Western Blot (WB)
Rabbit Trek1 Polyclonal Antibody | anti-Trek1 antibody
Trek1 Antibody
Gene Names
Kcnk2; TREK-1; AI848635; A430027H14Rik
Reactivity
Human (expected), Mouse, Rat (tested)
Applications
Western Blot
Purity
Affinity purified
Synonyms
Trek1; Polyclonal Antibody; Trek1 Antibody; K2p2.1; KCNK2; MGC126742; MGC126744; TPKC1; TREK; TREK-1; TREK1; hTREK-1c; hTREK-1e; anti-Trek1 antibody
Host
Rabbit
Reactivity
Human (expected), Mouse, Rat (tested)
Clonality
Polyclonal
Isotype
IgG
Specificity
The antibody recognizes ~47 kDa Trek 1 of mouse and rat origins. Reactivity to other species has not been tested
Purity/Purification
Affinity purified
Form/Format
0.5 mg/ml affinity purified rabbit anti-Trek-1 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.5 mM EDTA and 0.03% proclin
Concentration
0.5 mg/ml (varies by lot)
Sequence Length
426
Applicable Applications for anti-Trek1 antibody
Western Blot (WB)
Application Notes
Western blotting (0.5-4 ug/ml). However, the optimal conditions should be determined individually. The antibody recognizes ~47 kDa Trek 1 of human, mouse, and rat origins. Reactivity to other species has not been tested.
Immunogen
Synthetic peptide corresponding to residues surrounding amino acids 417 of mouse Trek-1
Handling
The antibody solution should be gently mixed before use.
Preparation and Storage
Store at -20 °C. For long-term storage, aliquot and freeze at -70 °C. Avoid repeated freeze-thaw cycles.
Western Blot (WB)
Western Blot (WB)
Related Product Information for anti-Trek1 antibody
Background: Trek-1 and Trek-2 belong to the tandem-pore K+ channel family that has two pore-forming domains and four transmembrane segments. Trek-1 is expressed thromughout the central nervous system whereas Trek-2 is found mostly in the cerebellum, spleen and testis. Trek-1 is activated by arachidonic acid and polyunsaturated fatty acids.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Official Full Name
TREK1
NCBI Official Synonym Full Names
potassium channel, subfamily K, member 2
NCBI Official Symbol
Kcnk2
NCBI Official Synonym Symbols
TREK-1; AI848635; A430027H14Rik
NCBI Protein Information
potassium channel subfamily K member 2
UniProt Protein Name
Potassium channel subfamily K member 2
UniProt Gene Name
Kcnk2
UniProt Entry Name
KCNK2_MOUSE
Uniprot Description
TREK-1: Outward rectifying potassium channel. Homodimer (Potential). Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, multi-pass; Channel, potassium; Membrane protein, integral
Cellular Component: voltage-gated potassium channel complex; membrane; endoplasmic reticulum; plasma membrane; integral to membrane
Molecular Function: protein binding; voltage-gated potassium channel activity; potassium channel activity; potassium ion leak channel activity; outward rectifier potassium channel activity; voltage-gated ion channel activity; potassium channel inhibitor activity
Biological Process: G-protein coupled receptor protein signaling pathway; regulation of membrane potential; transport; ion transport; potassium ion transport; stabilization of membrane potential
Research Articles on Trek1
Similar Products
Product Notes
The Trek1 kcnk2 (Catalog #AAA840722) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Trek1 Antibody reacts with Human (expected), Mouse, Rat (tested) and may cross-react with other species as described in the data sheet. AAA Biotech's Trek1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Western blotting (0.5-4 ug/ml). However, the optimal conditions should be determined individually. The antibody recognizes ~47 kDa Trek 1 of human, mouse, and rat origins. Reactivity to other species has not been tested. Researchers should empirically determine the suitability of the Trek1 kcnk2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Trek1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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