Macrophage Inflammatory protein-1 gamma Active Protein | mMIP-1g active protein
Recombinant Mouse Macrophage Inflammatory protein-1 gamma (CCL9)
Gene Names
Ccl9; CCF18; MRP-2; Scya9; Scya10
Purity
Greater than 97.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Synonyms
Macrophage Inflammatory protein-1 gamma; Recombinant Mouse Macrophage Inflammatory protein-1 gamma (CCL9); MIP-1 Gamma Mouse; Macrophage Inflammatory Protein-1 Gamma Mouse Recombinant (CCL9); CCL9/10; MRP2; CCF18; mMIP-1g active protein
Host
E Coli
Purity/Purification
Greater than 97.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Form/Format
The MIP-1 gamma was lyophilized from 1xPBS solution pH-7.4.
Sterile Filtered White lyophilized (freeze-dried) powder.
Sterile Filtered White lyophilized (freeze-dried) powder.
Sequence
QITHATETKE VQSSLKAQQG LEIEMFHMGF QDSSDCCLSY NSRIQCSRFI GYFPTSGGCT RPGIIFISKR GFQVCANPSD RRVQRCIERL EQNSQPRTYK Q
Sequence Length
122
Solubility
It is recommended to reconstitute the lyophilized MIP-1 gamma in sterile 18M-cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions.
Biological Activity
Defined by its ability to chemoattract human neutrophils using a concentration range of 0.1-10 ng/ml, corresponding to a Specific Activity of 10,000-100,000IU/mg.
Preparation and Storage
Lyophilized MIP-1 gamma although stable at room temperature for 3 weeks, should be stored desiccated below -18 degree C. Upon reconstitution CCL9/10 should be stored at 4 degree C between 2-7 days and for future use below -18 degree C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
Related Product Information for mMIP-1g active protein
Description: MIP-1 gamma Mouse Recombinant produced in E Coli is a single, non-glycosylated, polypeptide chain containing 101 amino acids and having a molecular mass of 11.6 kDa. The MIP-1 gamma is purified by proprietary chromatographic techniques.
Introduction: Mouse MIP-1 gamma is 75% identical in its amino acid compostion as compared to the rat specie. MIP-1 gamma is a CC chemokine localized in murine blood and a widespread range of murine tissues, without having an identified human homolog. MIP-1 gamma signals through the CCR1 receptor. MIP-1 gamma chemoattracts neutrophils and also inhibits colony formation of bone marrow myeloid immature progenitors. MIP-1 gamma has six cysteines including the four highly conserved cysteine residues present in CC chemokines.
Introduction: Mouse MIP-1 gamma is 75% identical in its amino acid compostion as compared to the rat specie. MIP-1 gamma is a CC chemokine localized in murine blood and a widespread range of murine tissues, without having an identified human homolog. MIP-1 gamma signals through the CCR1 receptor. MIP-1 gamma chemoattracts neutrophils and also inhibits colony formation of bone marrow myeloid immature progenitors. MIP-1 gamma has six cysteines including the four highly conserved cysteine residues present in CC chemokines.
Product Categories/Family for mMIP-1g active protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
13,871 Da
NCBI Official Full Name
C-C motif chemokine 9
NCBI Official Synonym Full Names
chemokine (C-C motif) ligand 9
NCBI Official Symbol
Ccl9
NCBI Official Synonym Symbols
CCF18; MRP-2; Scya9; Scya10
NCBI Protein Information
C-C motif chemokine 9; MIP-1 gamma; macrophage inflammatory protein 1-gamma; macrophage inflammatory protein-related protein 2; small inducible cytokine A10; small inducible cytokine A9
UniProt Protein Name
C-C motif chemokine 9
UniProt Gene Name
Ccl9
UniProt Synonym Gene Names
Mrp2; Scya10; Scya9; MIP-1-gamma; MRP-2
UniProt Entry Name
CCL9_MOUSE
Uniprot Description
CCL9: Monokine with inflammatory, pyrogenic and chemokinetic properties. Circulates at high concentrations in the blood of healthy animals. Binding to a high-affinity receptor activates calcium release in neutrophils. It also inhibits colony formation of bone marrow myeloid immature progenitors
Protein type: Cytokine
Cellular Component: extracellular space; extracellular region
Molecular Function: chemokine activity; cytokine activity
Biological Process: immune response; chemotaxis; negative regulation of myoblast differentiation
Research Articles on mMIP-1g
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Product Notes
The mMIP-1g ccl9 (Catalog #AAA144962) is an Active Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: QITHATETKE VQSSLKAQQG LEIEMFHMGF QDSSDCCLSY NSRIQCSRFI GYFPTSGGCT RPGIIFISKR GFQVCANPSD RRVQRCIERL EQNSQPRTYK Q. It is sometimes possible for the material contained within the vial of "Macrophage Inflammatory protein-1 gamma, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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