Typical Testing Data/Standard Curve (for reference only)
Urine Creatinine Detection Kit
Urine Creatinine Detection Kit
Reactivity
Human, Monkey, Dog, Rat
Synonyms
Urine Creatinine; Urine Creatinine Detection Kit; N-Carbamimidoyl-N-methylglycine Detection Kit; Methylguanidoacetic acid Detection Kit; Urine Creatinine detection kit
Reactivity
Human, Monkey, Dog, Rat
Samples
Human, monkey, dog, and rat urine
Intra-assay Precision
Four human urine samples were diluted 1:20 with deionized water and run in replicates of 20 in an assay.
Inter-assay Precision
Four human urine samples were diluted 1:20 with deionized water and run in duplicates in 20 assays run over five days by three operators.
Preparation and Storage
Store at 4 degree C
Typical Testing Data/Standard Curve (for reference only)
Typical Testing Data/Standard Curve (for reference only)
Related Product Information for Urine Creatinine detection kit
Background/Introduction: Creatinine (2-amino-1-methyl-5H-imadazol-4-one) is a metabolite of phosphocreatine (p-creatine), a molecule used as a store for high-energy phosphate that can be utilized by tissues for the production of ATP1. Creatine either comes from the diet or synthesized from the amino acids arginine, glycine, and methionine. This occurs in the kidneys and liver, although other organ systems may be involved and species-specific differences may exist2. Creatine and p-creatine are converted non-enzymatically to the metabolite creatinine, which diffuses into the blood and is excreted by the kidneys. In vivo, this conversion appears to be irreversible and in vitro it is favored by higher temperatures and lower pH2. Creatinine forms spontaneously from p-creatine3. Under normal conditions, its formation occurs at a rate that is relatively constant and as intra-individual variation is <15% from day to day, creatinine is a useful tool for normalizing the levels of other molecules found in urine. Additionally altered creatinine levels may be associated with other conditions that result in decreased renal blood flow such as diabetes and cardiovascular disease4-6.
Product Categories/Family for Urine Creatinine detection kit
References
1. Wallimann, T. et al., Biochem. J., 2000, 281, 21-40. 2. Wyss, M. and Kaddurah-Daouk, R., Physiol. Rev., 2000, 80, 1107-1213. 3. Raja Iyengar, M. et al., J. Biol. Chem, 1985, 260, 7562-7567. 4. Manjunath, G. et al., Postgrad. Med. 2001, 110, 55-62. 5. Gross, J.L. et al., Diabetes Care, 2005, 28, 164-176. 6. Anavekar, N.S. et al., New Engl. J. Med., 2004, 351, 1285-1295.
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Product Notes
The Human, Monkey, Dog, Rat Urine Creatinine (Catalog #AAA807896) is a Detection Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA807896 Detection Kit recognizes Human, Monkey, Dog, Rat Urine Creatinine. It is sometimes possible for the material contained within the vial of "Urine Creatinine, Detection Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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