Structure
Thymidine- 3', 5'- O- bisphosphate (pTp) / 2'- Deoxythymidine- 3', 5'- O- bisphosphate Biochemical
Thymidine- 3', 5'- O- bisphosphate (pTp) / 2'- Deoxythymidine- 3', 5'- O- bisphosphate
Purity
Typical analysis is better than 95% (HPLC / UV / 267 nm). The product is not sterile and has not been tested for endotoxins.
Synonyms
Thymidine- 3'; 5'- O- bisphosphate (pTp) / 2'- Deoxythymidine- 3'; 5'- O- bisphosphate; 5'- O- bisphosphate biochemical
Specificity
Crystallized or lyophilized sodium salt. For other salt forms or analogues of pTp please inquire. Please keep in mind that equal concentrations of the compound may look different in volume due to high sensitivity of the lyophilized form to humidity. The compound can even contract to small volume droplets. Normally the product is located in the conical bottom of the tube. Micromolar quantities are determined by UV at ?max.
Purity/Purification
Typical analysis is better than 95% (HPLC / UV / 267 nm). The product is not sterile and has not been tested for endotoxins.
Application Notes
Toxicity and Safety: Please keep in mind, that the in vivo properties of this compound are not sufficiently characterized up to now.
Avoid skin contact or ingestion and allow only trained personnel to handle the product.
Our products are designed, developed and sold for research purposes only! They are intended for in vitro and nonhuman in vivo laboratory applications. Any other use requires approval of health authorities.
Not for drug, household or related uses.
Avoid skin contact or ingestion and allow only trained personnel to handle the product.
Our products are designed, developed and sold for research purposes only! They are intended for in vitro and nonhuman in vivo laboratory applications. Any other use requires approval of health authorities.
Not for drug, household or related uses.
Formula
C10H16N2O11P2 for free acid
CAS No.
[2863-04-9]
UV
λ max 267 nm / ε 9600 / pH 7
Properties
pTp is a competitive inhibitor of staphylococcal nuclease and is accepted by T4 RNA ligase to build oligodeoxyribonucleotides.
Solubility
pTp has good solubility in water (> 100 mM). Please rinse tube walls carefully and preferably use ultrasonic or vortex to achieve total and uniform mixing. When opening the tube please make sure that no substance is lost within the cap.
Preparation and Storage
pTp is chemically rather stable and does not need special care during handling or shipment. Nevertheless, we recommend that the compound should be stored in the freezer, for longer storage periods preferably in freeze-dried form.
Structure
Structure
Related Product Information for Thymidine- 3', 5'- O- bisphosphate (pTp) / 2'- Deoxythymidine- 3', 5'- O- bisphosphate biochemical
In pTp phosphate groups are attached to both the ribose 3' position and the ribose 5' position of thymidine. Since thymidine already describes a 2'-deoxy nucleoside, the term "2'-deoxythymidine" is redundant.
Similar Products
Product Notes
The Thymidine- 3', 5'- O- bisphosphate (pTp) / 2'- Deoxythymidine- 3', 5'- O- bisphosphate (Catalog #AAA256407) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase. Toxicity and Safety: Please keep in mind, that the in vivo properties of this compound are not sufficiently characterized up to now. Avoid skin contact or ingestion and allow only trained personnel to handle the product. Our products are designed, developed and sold for research purposes only! They are intended for in vitro and nonhuman in vivo laboratory applications. Any other use requires approval of health authorities. Not for drug, household or related uses. Researchers should empirically determine the suitability of the Thymidine- 3', 5'- O- bisphosphate (pTp) / 2'- Deoxythymidine- 3', 5'- O- bisphosphate for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Thymidine- 3', 5'- O- bisphosphate (pTp) / 2'- Deoxythymidine- 3', 5'- O- bisphosphate, Biochemical" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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