Typical Testing Data/Standard Curve (for reference only)
Beta-Lactamase Inhibitor Assay Kit | BN672_00551 assay kit
Beta-Lactamase Inhibitor Screening Kit (Colorimetric)
Synonyms
Beta-Lactamase Inhibitor; Beta-Lactamase Inhibitor Screening Kit (Colorimetric); BN672_00551 assay kit
Sequence Length
200
Application Notes
Screening/studying/characterizing beta-Lactamase Inhibitors for efficient treatment of antibiotic resistant bacterial infections
Detection Method
Absorbance (490 nm)
Features & Benefits
Rapid, simple & sensitive
High-throughput suitable
Includes Inhibitor Control (Clavulanic Acid)
High-throughput suitable
Includes Inhibitor Control (Clavulanic Acid)
Preparation and Storage
At -20 degree C
Shelf Life: 12 months
Shelf Life: 12 months
Typical Testing Data/Standard Curve (for reference only)
Typical Testing Data/Standard Curve (for reference only)
Related Product Information for BN672_00551 assay kit
Product Information: Beta-Lactamase Inhibitor Screening Kit (Colorimetric): Simple, sensitive & high-throughput suitable assay to screen beta lactamase inhibitors. 100 assays.
Background: beta-Lactamase (betaL), (EC 3.5.2.6), is a bacterial enzyme that hydrolyzes the beta-Lactam ring, a four-carbon ring, the building block of beta-Lactam antibiotics. beta-Lactams inhibit transpeptidases, enzymes that participate in the biosynthesis of bacterial cell walls. Penams, Carbapenems, Cephems, Clavams, Oxacephems and Monobactams have been widely used for the treatment of bacterial infections since the discovery of penicillin, the first beta-Lactam antibiotic, and its bactericidal effect more than eighty years ago. However, an alarming number of cases of beta-Lactam antibiotic-resistant infections have been reported. The resistance is found in bacterial strains producing beta-Lactamase, which is responsible for diminishing the beta-Lactam antibiotic potency. beta-Lactamase inhibition, therefore, has become an urgent target in the treatment of bacterial infections displaying beta-Lactam resistance. Several beta-Lactam derivatives have been reported as beta-Lactamase inhibitors; however, only clavulanic acid, sulbactam and tazobactam have reached clinical importance. MyBioSource's beta-Lactamase Inhibitor Screening Kit utilizes the ability of the enzyme to hydrolyze Nitrocefin, a well-known beta-Lactamase substrate. In the presence of Clavulanic Acid-a potent inhibitor of beta-Lactamase, the rate of hydrolysis of the substrate is decreased. The kit provides a rapid, simple, sensitive, and reliable test suitable for high- throughput screening of beta-Lactamase inhibitors.
Summary: Detection method: Absorbance (490 nm)
Application: Screening/studying/characterizing beta-Lactamase Inhibitors for efficient treatment of antibiotic resistant bacterial infections
Background: beta-Lactamase (betaL), (EC 3.5.2.6), is a bacterial enzyme that hydrolyzes the beta-Lactam ring, a four-carbon ring, the building block of beta-Lactam antibiotics. beta-Lactams inhibit transpeptidases, enzymes that participate in the biosynthesis of bacterial cell walls. Penams, Carbapenems, Cephems, Clavams, Oxacephems and Monobactams have been widely used for the treatment of bacterial infections since the discovery of penicillin, the first beta-Lactam antibiotic, and its bactericidal effect more than eighty years ago. However, an alarming number of cases of beta-Lactam antibiotic-resistant infections have been reported. The resistance is found in bacterial strains producing beta-Lactamase, which is responsible for diminishing the beta-Lactam antibiotic potency. beta-Lactamase inhibition, therefore, has become an urgent target in the treatment of bacterial infections displaying beta-Lactam resistance. Several beta-Lactam derivatives have been reported as beta-Lactamase inhibitors; however, only clavulanic acid, sulbactam and tazobactam have reached clinical importance. MyBioSource's beta-Lactamase Inhibitor Screening Kit utilizes the ability of the enzyme to hydrolyze Nitrocefin, a well-known beta-Lactamase substrate. In the presence of Clavulanic Acid-a potent inhibitor of beta-Lactamase, the rate of hydrolysis of the substrate is decreased. The kit provides a rapid, simple, sensitive, and reliable test suitable for high- throughput screening of beta-Lactamase inhibitors.
Summary: Detection method: Absorbance (490 nm)
Application: Screening/studying/characterizing beta-Lactamase Inhibitors for efficient treatment of antibiotic resistant bacterial infections
Product Categories/Family for BN672_00551 assay kit
NCBI and Uniprot Product Information
NCBI GI #
Molecular Weight
22,252 Da
NCBI Official Full Name
beta-lactamase inhibitor
UniProt Protein Name
Beta-lactamase inhibitor
Protein Family
UniProt Gene Name
BN672_00551
UniProt Entry Name
R7HEX4_9MOLU
Similar Products
Product Notes
The Beta-Lactamase Inhibitor bn672_00551 (Catalog #AAA841622) is an Assay Kit and is intended for research purposes only. The product is available for immediate purchase. Screening/studying/characterizing beta-Lactamase Inhibitors for efficient treatment of antibiotic resistant bacterial infections. Researchers should empirically determine the suitability of the Beta-Lactamase Inhibitor bn672_00551 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Beta-Lactamase Inhibitor, Assay Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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