Testing Data
Activated Protein C (APC) Assay Kit
Activated Protein C (APC) Inhibitor Screening Kit (Colorimetric)
Synonyms
Activated Protein C (APC); Activated Protein C (APC) Inhibitor Screening Kit (Colorimetric); Activated Protein C (APC) assay kit
Detection Method
Colorimetric: OD 405nm
Features & Benefits
High-throughput compatible
Quick and easy screening for Activated Protein C ligands; Includes human recombinant APC
Simple, highly sensitive
High-throughput compatible
Rapid screening of Activated Protein C ligands
Kit includes PPACK (APC inhibitor) and a stable, recombinant human APC
Screening of drugs and novel ligands for interaction with human recombinant Activated Protein C
Quick and easy screening for Activated Protein C ligands; Includes human recombinant APC
Simple, highly sensitive
High-throughput compatible
Rapid screening of Activated Protein C ligands
Kit includes PPACK (APC inhibitor) and a stable, recombinant human APC
Screening of drugs and novel ligands for interaction with human recombinant Activated Protein C
Preparation and Storage
Store at -20 degree C
Shelf life: ~12 months
Shelf life: ~12 months
Testing Data
Testing Data
Related Product Information for Activated Protein C (APC) assay kit
Activated protein C (APC) (3.4.21.69), a Vitamin K dependent serine protease, is formed by activation of Protein C by Thrombomodulin bound on the surface of endothelial cells. By degrading coagulation factors Va and VIIIa, APC inhibits blood coagulation which helps in the prevention of thrombosis. Blood coagulation can be stimulated by inhibition of APC. Thus, APC inhibitors play an important role in the treatment of disease like Haemophilia. APC Inhibitor Screening Kit can be used to screen for potent inhibitors of APC activity. It utilizes the proteolytic activity of an active APC on a peptide substrate which releases a colored product. The released product can be easily quantified using an absorbance microplate reader. In the presence of an APC inhibitor, the enzyme decreases/loses activity resulting in lower/no absorbance. This assay kit is simple and can be used to identify and characterize APC inhibitors in a high-throughput format. As a control, we provide the inhibitor PPACK dihydrochloride - a known APC inhibitor.
Product Categories/Family for Activated Protein C (APC) assay kit
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Product Notes
The Activated Protein C (APC) (Catalog #AAA849651) is an Assay Kit and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Activated Protein C (APC), Assay Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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