SDS-Page
GFR alpha-like Recombinant Protein | GFRAL recombinant protein
Human CellExp GFR alpha-like, Human Recombinant
Gene Names
GFRAL; GRAL; UNQ9356; C6orf144; bA360D14.1
Purity
>95% as determined by SDS-PAGE.
Synonyms
GFR alpha-like; Human CellExp GFR alpha-like; Human Recombinant; GFR alpha like; GFRAL; GRAL; GFRAL recombinant protein
Host
HEK293 cells
Purity/Purification
>95% as determined by SDS-PAGE.
Form/Format
Lyophilized powder. Lyophilized from 0.22um filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization
Sequence
aaSer19-Glu351
Gene Source
Human
Endotoxin
Less than 1.0 EU per ug by the LAL method
Reconstitution Instruction
Reconstitute in sterile deionized water to a concentration of 100 ug/ml. Do not vortex. It is recommended to store at store at -20 degree C.
Tag Note
This protein carries a polyhistidine tag at the C-terminus.
Preparation and Storage
Store at -20 degree C
Centrifuge the vial prior to opening.
Shelf life: ~12 months
Centrifuge the vial prior to opening.
Shelf life: ~12 months
SDS-Page
SDS-Page
Related Product Information for GFRAL recombinant protein
GFR alpha-like is also known as GDNF family receptor alpha-like, GFRAL, C6orf144, UNQ9356, PRO34128. Growth differentiation factor-15 (GDF15) is a circulating protein that has been implicated in multiple biological processes, including energy homeostasis, body weight regulation, and cachexia driven by cancer and chronic disease. GDNF family receptor alpha-like (GFRAL) was recently identified as the neuronal brainstem receptor responsible for mediating the anorectic actions of GDF15. Brainstem-restricted receptor for GDF15 which regulates food intake, energy expenditure and body weight in response to metabolic and toxin-induced stresses. Upon interaction with its ligand, GDF15, interacts with RET and induces cellular signaling through activation of MAPK- and AKT- signaling pathways. Neuronal brainstem receptor mediating the anorectic funtions of GDF15
Product Categories/Family for GFRAL recombinant protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
44,518 Da
NCBI Official Full Name
GDNF family receptor alpha-like
NCBI Official Synonym Full Names
GDNF family receptor alpha like
NCBI Official Symbol
GFRAL
NCBI Official Synonym Symbols
GRAL; UNQ9356; C6orf144; bA360D14.1
NCBI Protein Information
GDNF family receptor alpha-like; IVFI9356
UniProt Protein Name
GDNF family receptor alpha-like
Protein Family
UniProt Gene Name
GFRAL
UniProt Synonym Gene Names
C6orf144; UNQ9356/PRO34128
UniProt Entry Name
GFRAL_HUMAN
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Product Notes
The GFRAL gfral (Catalog #AAA8400010) is a Recombinant Protein produced from HEK293 cells and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: aaSer19-Gl u351. It is sometimes possible for the material contained within the vial of "GFR alpha-like, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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