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Neuroligin-4, Y-linked/NLGN4Y Recombinant Protein | NLGN4Y recombinant protein

Human CellExp Neuroligin-4, Y-linked/NLGN4Y, Human Recombinant

Purity
>90% as determined by SDS-PAGE
Synonyms
Neuroligin-4; Y-linked/NLGN4Y; Human CellExp Neuroligin-4; Human Recombinant; NLGN4Y; neuroligin 4; Y-linked; NLGN4Y1; NLGN4Y recombinant protein
Ordering
For Research Use Only!
Host
HEK293 cells
Purity/Purification
>90% as determined by SDS-PAGE
Form/Format
Lyophilized powder. Lyophilized from 0.22um filtered solution in PBS, pH7.4. Normally trehaloseis added as protectant before lyophilization.
Sequence
aaGln44-Ser676
Gene Source
Human
Endotoxin
Less than 1.0 EU per ug by the LAL method
Reconstitution Instruction
Reconstitute in sterile deionized water to a concentration of 100 ug/ml. Do not vortex. It is recommended to store at store at -20 degree C.
Tag Note
This protein carries a polyhistidine tag at the C-terminus.
Preparation and Storage
Store at -20 degree C
Centrifuge the vial prior to opening.
Shelf life: ~12 months

SDS-Page

SDS-Page
Related Product Information for NLGN4Y recombinant protein
Neuroligin 4, Y-linked (NLGN4Y) a type I membrane protein that belongs to the family of neuroligins, which are cell adhesion molecules present at the postsynaptic side of the synapse, and may be essential for the formation of functional synapses. Alternatively spliced transcript variants have been found for NLGN4Y gene. NLGN4Y was expressed in fetal and adult brain, prostate, testis, pancreas. NLGN4Y is homologous with its X-linked homolog, NLGN4X. Putative neuronal cell surface protein involved in cell-cell-interactions

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
816
NCBI Official Full Name
Neuroligin-4, Y-linked
NCBI Official Synonym Full Names
neuroligin 4, Y-linked
NCBI Official Symbol
NLGN4Y
NCBI Protein Information
neuroligin-4, Y-linked
UniProt Protein Name
Neuroligin-4, Y-linked
Protein Family
UniProt Gene Name
NLGN4Y
UniProt Synonym Gene Names
KIAA0951; Neuroligin Y
UniProt Entry Name
NLGNY_HUMAN

NCBI Description

This gene encodes a type I membrane protein that belongs to the family of neuroligins, which are cell adhesion molecules present at the postsynaptic side of the synapse, and may be essential for the formation of functional synapses. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Mar 2011]

Uniprot Description

NLGN4Y: Putative neuronal cell surface protein involved in cell- cell-interactions. Belongs to the type-B carboxylesterase/lipase family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: Yq11.221

Cellular Component: postsynaptic membrane; extracellular space; cell surface; integral to plasma membrane; postsynaptic density; synapse; cell junction

Molecular Function: protein binding; neurexin binding; receptor activity; cell adhesion molecule binding

Biological Process: regulation of synaptic transmission; synaptogenesis; metabolic process; neuron adhesion; social behavior; learning

Research Articles on NLGN4Y

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Product Notes

The NLGN4Y nlgn4y (Catalog #AAA8400011) is a Recombinant Protein produced from HEK293 cells and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: aaGln44-Se r676. It is sometimes possible for the material contained within the vial of "Neuroligin-4, Y-linked/NLGN4Y, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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