Structure
SG85, Inhibitor
SG85
Purity
>98% (HPLC)
Synonyms
SG85; SG 85; inhibitor
Purity/Purification
>98% (HPLC)
Target
Enterovirus
Receptor
Enterovirus
Chemical Name
ethyl(5S, 8S, 11S, E)-8-benzyl-5-(tert-butoxymethyl)-3, 6, 9-trioxo-11-(((S)-2-oxopyrrolidin-3-yl)methyl)-1-phenyl-2-oxa-4, 7, 10-triazatetradec-12-en-14-oate
Molecular Formula
C35H46N4O8
CAS Number
1575662-24-6
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Stability: >=2 years
Shipping: Ice Pack
Structure
Structure
Related Product Information for SG85, inhibitor
SG85 is a potent Enterovirus 3C protease inhibitor with EC50 of 180nM against EV71 and 60nM against human rhinovirus 14 in a live virus-cell-based assay; effectively inhibits the in vitro replication of 14 rhinoviruses representative of species A and B with mean EC50 of 40nM, efficiently blocks rhinovirus replication and is not cross-resistant with rupintrivir.
Product Categories/Family for SG85, inhibitor
References
1. Tijsma A, et al. Antimicrob Agents Chemother. 2014 Nov; 58 (11):6990-2.
2. Tan J, et al. J Virol. 2013 Apr; 87 (8):4339-51.
3. Lacroix C, et al. Antimicrob Agents Chemother. 2015 Sep; 59 (9):5814-8.
2. Tan J, et al. J Virol. 2013 Apr; 87 (8):4339-51.
3. Lacroix C, et al. Antimicrob Agents Chemother. 2015 Sep; 59 (9):5814-8.
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Product Notes
The SG85 (Catalog #AAA3602250) is an Inhibitor and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "SG85, Inhibitor" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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