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Structure

Rupintrivir, Inhibitor

Rupintrivir

Purity
>98% (HPLC)
Synonyms
Rupintrivir; AG-7088; AG7088; inhibitor
Ordering
Purity/Purification
>98% (HPLC)
Target
Rhinovirus
Receptor
Rhinovirus
Chemical Name
Ethyl(2E, 4S)-4-[[(2R, 5S)-2-[(4-fluorophenyl)methyl]-6-methyl-5-[[(5-methyl-3-isoxazolyl)carbonyl]amino]-1, 4-dioxoheptyl]amino]-5-[(3S)-2-oxo-3-pyrrolidinyl]-2-pentenoate
SMILES
O=C(OCC)/C=C/[C@@H](NC([C@H](CC1=CC=C(F)C=C1)CC([C@@H](NC(C2=NOC(C)=C2)=O)C(C)C)=O)=O)C[C@H]3C(NCC3)=O
Molecular Formula
C31H39FN4O7
CAS Number
223537-30-2
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack

Structure

Structure
Related Product Information for Rupintrivir, inhibitor
Rupintrivir (AG-7088, AG7088) is a potent, irreversible inhibitor of human rhinovirus 3C protease, inhibits the replication of all HRV serotypes with EC50 of 23nM and EC90 of 82nM; potently and irreversibly inhibits HRV 3C protease with an inactivation rate constant (kobs/ [I]) of 1, 470,000 +/- 440,000 M-1 s-1 for HRV 14; also potently inhibits related picornaviruses including coxsackieviruses A21 and B3, enterovirus 70, and echovirus 11. Rhinovirus Infection Phase 2 Clinical
Product Categories/Family for Rupintrivir, inhibitor
References
1. Patick AK, et al. Antimicrob Agents Chemother. 1999 Oct; 43 (10):2444-50.
2. Dragovich PS, et al. J Med Chem. 1999 Apr 8; 42 (7):1213-24.
3. Matthews DA, et al. Proc Natl Acad Sci U S A. 1999 Sep 28; 96 (20):11000-7.
4. Zalman LS, et al. Antimicrob Agents Chemother. 2000 May; 44 (5):1236-41.

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Product Notes

The Rupintrivir (Catalog #AAA3603583) is an Inhibitor and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Rupintrivir, Inhibitor" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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