Western Blot (WB)
(Western Blot detection against Immunogen (34.36kD).)
Mouse anti-Human SFRS6 Monoclonal Antibody | anti-SFRS6 antibody
SFRS6 (Serine/Arginine-rich Splicing Factor 6, Pre-mRNA-splicing Factor SRP55, Splicing Factor, Arginine/Serine-rich 6, SFRS6, SRP55, FLJ08061, MGC5045) (PE)
Western Blot (WB)
(Western Blot detection against Immunogen (34.36kD).)
Western Blot (WB)
(Western Blot detection against Immunogen (34.36kD).)
Western Blot (WB)
(Western Blot analysis of SFRS6 expression in transfected 293T cell line by SFRS6 monoclonal antibody. Lane 1: SFRS6 transfected lysate (39.6kD). Lane 2: Non-transfected lysate.)
Western Blot (WB)
(Western Blot analysis of SFRS6 expression in transfected 293T cell line by SFRS6 monoclonal antibody. Lane 1: SFRS6 transfected lysate (39.6kD). Lane 2: Non-transfected lysate.)
Testing Data
(Detection limit for recombinant GST tagged SFRS6 is ~0.3ng/ml as a capture antibody.)
Testing Data
(Detection limit for recombinant GST tagged SFRS6 is ~0.3ng/ml as a capture antibody.)
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is involved in mRNA splicing and may play a role in the determination of alternative splicing. The encoded nuclear protein belongs to the splicing factor SR family and has been shown to bind with and modulate another member of the family, SFRS12. Alternative splicing results in multiple transcript variants. In addition, two pseudogenes, one on chromosome 17 and the other on the X chromosome, have been found for this gene.[provided by RefSeq, Sep 2010]
Uniprot Description
SFRS6: Plays a role in constitutive splicing and can modulate the selection of alternative splice sites. Represses the splicing of MAPT/Tau exon 10. Belongs to the splicing factor SR family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Spliceosome; RNA-binding; RNA splicing
Chromosomal Location of Human Ortholog: 20q12-q13.1
Cellular Component: nucleoplasm; nuclear speck
Molecular Function: RNA binding; nucleotide binding
Biological Process: alternative nuclear mRNA splicing, via spliceosome; transcription from RNA polymerase II promoter; nuclear mRNA splicing, via spliceosome; mRNA splice site selection; mRNA export from nucleus; negative regulation of nuclear mRNA splicing, via spliceosome; RNA splicing; negative regulation of keratinocyte differentiation; gene expression; mRNA 3'-end processing; termination of RNA polymerase II transcription; regulation of alternative nuclear mRNA splicing, via spliceosome
Research Articles on SFRS6
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Product Notes
The SFRS6 srsf6 (Catalog #AAA6160225) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The SFRS6 (Serine/Arginine-rich Splicing Factor 6, Pre-mRNA-splicing Factor SRP55, Splicing Factor, Arginine/Serine-rich 6, SFRS6, SRP55, FLJ08061, MGC5045) (PE) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's SFRS6 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the SFRS6 srsf6 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SFRS6, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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