Structure
HBV Capsid inhibitor 3711, Inhibitor
HBV Capsid inhibitor 3711
Purity
>98% (HPLC)
Synonyms
HBV Capsid inhibitor 3711; Compound 3711; inhibitor
Purity/Purification
>98% (HPLC)
Target
HBV
Receptor
HBV
Chemical Name
N-(4-(1-(4-chlorobenzyl)-5-methyl-6-oxo-1, 6-dihydropyridazin-3-yl)phenyl)acetamide
Molecular Formula
C20H18ClN3O2
CAS Number
2041072-40-4
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Stability: >=2 years
Shipping: Ice Pack
Structure
Structure
Related Product Information for HBV Capsid inhibitor 3711, inhibitor
HBV Capsid inhibitor 3711 (Compound 3711) is a nonnucleosidic HBV inhibitor, inhibits hepatitis B virus replication by inducing genome-free capsid formation; decreases extracellular HBV DNA levels and intracellular DNA levels with EC50 of 1.5 and 1.9uM in a cell model system; shows sensitivity against both the 3TC/ETV dually resistant L180M/M204I mutant and the adefovir (ADV)-resistant A181T/N236T mutant; decreases levels of HBV DNA contained in both secreted enveloped virion and naked virus particles in supernatant, interferes with capsid formation of the core protein (Cp) assembly domain.
Product Categories/Family for HBV Capsid inhibitor 3711, inhibitor
References
1. Feng S, et al. ACS Infect Dis. 2018 Mar 9; 4 (3):257-277.
2. Wang YJ, et al. Antimicrob Agents Chemother. 2015 Nov; 59 (11):7061-72.
2. Wang YJ, et al. Antimicrob Agents Chemother. 2015 Nov; 59 (11):7061-72.
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Product Notes
The HBV Capsid inhibitor 3711 (Catalog #AAA3603173) is an Inhibitor and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "HBV Capsid inhibitor 3711, Inhibitor" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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