Cystatin 5 Active Protein | CST5 active protein
Recombinant Human Cystatin 5
Purity
Greater than 90.0% as determined by SDS-PAGE.
Synonyms
Cystatin 5; Recombinant Human Cystatin 5; CST5 Human; Cystatin 5 Human Recombinant; Cystatin-D; CST5; Cystatin-5; CST5 active protein
Host
E Coli
Purity/Purification
Greater than 90.0% as determined by SDS-PAGE.
Form/Format
The CST5 solution (0.5mg/1ml) contains phosphate buffered saline (pH7.4) and 10% glycerol.
Sterile Filtered clear solution.
Sterile Filtered clear solution.
Sequence
QSRTLAGGIH ATDLNDKSVQ RALDFAISEY NKVINKDEYY SRPLQVMAAY QQIVGGVNYY FNVKFGRTTC TKSQPNLDNC PFNDQPKLKE EEFCSFQINE VPWEDKISIL NYKCRKVHHH HHH.
Sequence Length
142
Biological Activity
The IC50 value is < 2.0nM. The inhibitory function of Cystatin 5 on protease activity of papain was measured by a fluorometric assay using Z-FR-AMC at pH 7.5 at 25C.
Related Product Information for CST5 active protein
Introduction: Cystatin 5 (CST5) is a novel member of the cystatin superfamily, which encompasses proteins that contain multiple cystatin-like sequences. Some members are active cysteine protease inhibitors, while others have lost or possibly never had this inhibitory activity. The superfamily is comprised of 3 inhibitory families: the type 1 cystatins (stefins), type 2 cystatins and the kininogens. Type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in various human fluids and secretions.
Description: CST5 Human Recombinant produced in E Coli is a single polypeptide chain containing 123 amino acids (26-142) and having a molecular mass of 14.36kDa.CST5 is fused to a 6 amino acid His-tag at C-terminus & purified by proprietary chromatographic techniques.
Description: CST5 Human Recombinant produced in E Coli is a single polypeptide chain containing 123 amino acids (26-142) and having a molecular mass of 14.36kDa.CST5 is fused to a 6 amino acid His-tag at C-terminus & purified by proprietary chromatographic techniques.
Product Categories/Family for CST5 active protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
16,080 Da
NCBI Official Full Name
cystatin-D
NCBI Official Synonym Full Names
cystatin D
NCBI Official Symbol
CST5
NCBI Protein Information
cystatin-D
UniProt Protein Name
Cystatin-D
Protein Family
UniProt Gene Name
CST5
UniProt Entry Name
CYTD_HUMAN
Uniprot Description
CST5: Cysteine proteinase inhibitor that possibly plays a protective role against proteinases present in the oral cavity. The order of preference for inhibition is cathepsin S > cathepsin H > cathepsin L > cathepsin B. Belongs to the cystatin family.
Protein type: Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 20p11.21
Cellular Component: extracellular region; extracellular space
Molecular Function: cysteine protease inhibitor activity; protease binding; protein binding
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Product Notes
The CST5 cst5 (Catalog #AAA140814) is an Active Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: QSRTLAGGIH ATDLNDKSVQ RALDFAISEY NKVINKDEYY SRPLQVMAAY QQIVGGVNYY FNVKFGRTTC TKSQPNLDNC PFNDQPKLKE EEFCSFQINE VPWEDKISIL NYKCRKV HHH HHH.. It is sometimes possible for the material contained within the vial of "Cystatin 5, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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