Tumor necrosis factor receptor superfamily member 11A (Tnfrsf11a) Recombinant Protein | Tnfrsf11a recombinant protein
Recombinant Mouse Tumor necrosis factor receptor superfamily member 11A (Tnfrsf11a)
NCBI and Uniprot Product Information
Uniprot Description
TNFRSF11A: Receptor for TNFSF11/RANKL/TRANCE/OPGL; essential for RANKL-mediated osteoclastogenesis. Involved in the regulation of interactions between T-cells and dendritic cells. Binds to the clefts between the subunits of the TNFSF11 ligand trimer to form a heterohexamer. Interacts with TRAF1, TRAF2, TRAF3, TRAF5 and TRAF6. Interacts (via cytoplasmic domain) with GAB2. Ubiquitous expression with high levels in skeletal muscle, thymus, liver, colon, small intestine and adrenal gland.
Protein type: Membrane protein, integral
Cellular Component: cell surface; membrane; integral to membrane; plasma membrane; external side of plasma membrane
Molecular Function: protein binding; transmembrane receptor activity; tumor necrosis factor receptor activity; metal ion binding; cytokine binding
Biological Process: circadian thermoregulation; positive regulation of JNK activity; ossification; adaptive immune response; tumor necrosis factor-mediated signaling pathway; response to cytokine stimulus; multicellular organismal development; programmed cell death; response to lipopolysaccharide; positive regulation of transcription factor activity; osteoclast differentiation; lymph node development; activation of NF-kappaB transcription factor
Research Articles on Tnfrsf11a
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Product Notes
The Tnfrsf11a tnfrsf11a (Catalog #AAA1257854) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 31-214. The amino acid sequence is listed below: VTPPCTQERH YEHLGRCCSR CEPGKYLSSK CTPTSDSVCL PCGPDEYLDT WNEEDKCLLH KVCDAGKALV AVDPGNHTAP RRCACTAGYH WNSDCECCRR NTECAPGFGA QHPLQLNKDT VCTPCLLGFF SDVFSSTDKC KPWTNCTLLG KLEAHQGTTE SDVVCSSSMT LRRPPKEAQA YLPS. It is sometimes possible for the material contained within the vial of "Tumor necrosis factor receptor superfamily member 11A (Tnfrsf11a), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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