Chemical Structure
(Chemical structure of Spautin-1 (SIH-404), a Autophagy inhibitor. CAS #: 1262888-28-7. Molecular Formula: C15H11F2N3. Molecular Weight: 271.26 g/mol.)
Spautin-1 Small Molecule
Spautin-1
Purity
>=98%
Synonyms
Spautin-1; Autophagy inhibitor; 6-Fluoro-N-[(4-fluorophenyl)methyl]-4-quinazolinamine; Spautin-1 small molecule
Host
Synthetic
Purity/Purification
>=98%
Form/Format
White to beige powder.
Solubility
Soluble in DMSO (15 mg/ml).
CAS Number
1262888-28-7
Molecular Formula
C15H11F2N3
SMILES
c1cc(ccc1CNc2c3cc(ccc3ncn2)F)F
InChI
1S/C15H11F2N3/c16-11-3-1-10(2-4-11)8-18-15-13-7-12(17)5-6-14(13)19-9-20-15/h1-7,9H,8H2,(H,18,19,20)
InChI Key
AWIVHRPYFSSVOG-UHFFFAOYSA-N
PubChem CID
51037431
Preparation and Storage
Store at -20 degree C.
Chemical Structure
(Chemical structure of Spautin-1 (SIH-404), a Autophagy inhibitor. CAS #: 1262888-28-7. Molecular Formula: C15H11F2N3. Molecular Weight: 271.26 g/mol.)
Chemical Structure
(Chemical structure of Spautin-1 (SIH-404), a Autophagy inhibitor. CAS #: 1262888-28-7. Molecular Formula: C15H11F2N3. Molecular Weight: 271.26 g/mol.)
Related Product Information for Spautin-1 small molecule
Spautin-1 inhibits the deubiquitination activity of USP10 and USP13, two ubiquitin-specific peptidases. This results in the degradation of class III PI3 kinase complexes. Because this group of kinases regulates autophagy, Spautin-1 in turn inhibits autophagy.
Product Categories/Family for Spautin-1 small molecule
References
1. Liu J., et al. (2011) Cell. 147(1): 223-34.
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Product Notes
The Spautin-1 (Catalog #AAA808108) is a Small Molecule produced from Synthetic and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Spautin-1, Small Molecule" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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