Chemical Structure
(Methyl N-(5-thenoyl-2-benzimidazolyl)carbamate; Methyl [5-(2-thienylcarbonyl)-1H-benzimidazol-2-yl]carbamate; Oncodazole; R 17934; [5-(2-Thienylcarbonyl)-1H-benzimidazol-2-yl]-carbamic acid methyl ester)
Nocodazole Solution in DMSO Biochemical
Nocodazole Solution in DMSO, 5mg/ml
Purity
Nocodazole: >=99% (HPLC); DMSO: >=99.9%
Synonyms
Nocodazole Solution in DMSO; 5mg/ml; Methyl N-(5-thenoyl-2-benzimidazolyl)carbamate; Methyl [5-(2-thienylcarbonyl)-1H-benzimidazol-2-yl]carbamate; Oncodazole; R 17934; [5-(2-Thienylcarbonyl)-1H-benzimidazol-2-yl]-carbamic acid methyl ester; Nocodazole Solution in DMSO biochemical
Host
Synthetic
Purity/Purification
Nocodazole: >=99% (HPLC); DMSO: >=99.9%
Form/Format
Supplied as a liquid in DMSO.
Concentration
5mg/ml (varies by lot)
CAS Number
31430-18-9
Grade
Molecular Biology Grade
Molecular Formula
C14H11N3O3S
Preparation and Storage
May be stored at RT for short-term only. Long-term storage is recommended at 4 degree C for 6 months after receipt.
Chemical Structure
(Methyl N-(5-thenoyl-2-benzimidazolyl)carbamate; Methyl [5-(2-thienylcarbonyl)-1H-benzimidazol-2-yl]carbamate; Oncodazole; R 17934; [5-(2-Thienylcarbonyl)-1H-benzimidazol-2-yl]-carbamic acid methyl ester)
Chemical Structure
(Methyl N-(5-thenoyl-2-benzimidazolyl)carbamate; Methyl [5-(2-thienylcarbonyl)-1H-benzimidazol-2-yl]carbamate; Oncodazole; R 17934; [5-(2-Thienylcarbonyl)-1H-benzimidazol-2-yl]-carbamic acid methyl ester)
Related Product Information for Nocodazole Solution in DMSO biochemical
Nocodazole, an inhibitor of microtubule formation, was found to greatly inhibit cell division around the mound stage as well as during the vegetative growth phase, when applied to exponentially growing Ax-2 cells. Mitotic arrest of cells with nocodazole can be used to study phosphorylation of microtubule-associated proteins which increase during mitosis, concomitant with increased microtubule dynamics. Nocodazole has been found to dramatically inhibit T cell antigen receptor (TCR) signaling, independently of its ability to depolymerize microtubules. Nocodazole arrests the cell cycle at G2/M phase and prevents phosphorylation of the T cell antigen receptor and inhibits its activity.
Product Categories/Family for Nocodazole Solution in DMSO biochemical
References
1. Jones, M. H. et al., (1999) Mol. Biol. Cell 10: 2377-2391. 2. Rennison, M.E., et al., (1992) J. Cell Sci. 102:239. 3. Fleischman, L.F., et al., (1993) Oncogene 8:771. 4. Amon, I., et al., (1994) 77:1037-1050. 5. Araki, T., Maeda, Y., (1998) Zoolog. Sci. 15(1):77-84. 6. llenberger, S., et al., (1998) Mol. Biol. Cell. 9(6):1495-1512. 7. Huby, R.D., et al.,(1998) J. Biol. Chem.15,273(20):12024-12031.
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Product Notes
The Nocodazole Solution in DMSO (Catalog #AAA6120681) is a Biochemical produced from Synthetic and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Nocodazole Solution in DMSO, Biochemical" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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