Structure
Flubendazole Biochemical
Flubendazole
Purity
0.997
Synonyms
Flubendazole; methyl N-[6- (4-fluorobenzoyl)-1H-benzimidazol-2-yl]carbamate; Flumoxane; Fluvermal; Flubendazol; fluoromebendazole; Flubenol; Flubendazolum; Flumoxal; Flumoxanal; Flutelmium; NSC 313680; Flubendazole biochemical
Purity/Purification
0.997
Form/Format
Solid
Solubility
~1 mg/ml in ethanol
DMSO and water
DMSO and water
Molecular Formula
C??H??FN?O?
CAS Number
31430-15-6
MDL Number
MFCD00871999
PubChem CID
35802
SMILES
COC (=O)NC1=NC2=C (N1)C=C (C=C2)C (=O)C3=CC=C (C=C3)F
InChi
InChI=1S/C16H12FN3O3/c1-23-16 (22)20-15-18-12-7-4-10 (8-13 (12)19-15)14 (21)9-2-5-11 (17)6-3-9/h2-8H,1H3, (H2,18,19,20,22)
InChi Key
CPEUVMUXAHMANV-UHFFFAOYSA-N
Preparation and Storage
Store at -20 degree C
Shelf life: ~36months
Shelf life: ~36months
Structure
Structure
Related Product Information for Flubendazole biochemical
Flubendazole is a benzimidazole carbamate anthelmintic agent. It eliminates larvae in a mouse model of A. cantonensis infection and exhibits a mean larval reduction of 100% in a T. spiralis infection model when administered at doses of 5 and 50 mg/kg per day, respectively. It disrupts tubulin polymerization by showing preference for binding to nematode tubulin rather than the tubulin in host. Flubendazole inhibits mammalian tubulin polymerization with an IC50 of 2.5 uM. The microtubule-disrupting properties of benzimidazoles cause potential anti-cancer activity. The IC50 values for inhibition of proliferation of MDA-MB-231, BT-549, MCF-7 and SK-BR-3 cells are 1.75 uM, 0.72 uM, 5.51 uM and 1.51 uM, respectively.
Product Categories/Family for Flubendazole biochemical
References
https://pubchem.ncbi.nlm.nih.gov/compound/35802
Similar Products
Product Notes
The Flubendazole (Catalog #AAA849050) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Flubendazole, Biochemical" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
