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35 results for "insulin-like-growth-factor-binding-protein-3-receptor" - showing 1-35


transmembrane protein 219, ELISA Kit (Cat# AAA9341285)

Full Name
Human Transmembrane protein 219, TMEM219 ELISA Kit
Gene Names
TMEM219; IGFBP-3R
Reactivity
Human
Pricing
$540/48-Strip-Wells | $755/96-Strip-Wells | $3,410/5x96-Strip-Wells | $6,715/10x96-Strip-Wells
Activity Data (Figure. The binding activity of IGF2 with EMMPRIN.Insulin-like growth factor 2 (IGF2) is one of three protein hormones that share structural similarity to insulin. It has growth-regulating, insulin-like and mitogenic activities. IGF2 exerts its effects by binding to the IGF-1 receptor and to the short isoform of the insulin receptor. IGF2 may also bind to the IGF2 receptor (also called the cation-independent mannose 6-phosphate receptor), which acts as a signalling antagonist; that is, to prevent IGF2 responses. Besides, Extracellular Matrix Metalloproteinase Inducer (EMMPRIN) has been identified as an interactor of IGF2, thus a binding ELISA assay was conducted to detect the interaction of recombinant human IGF2 and recombinant human EMMPRIN. Briefly, IGF2 were diluted serially in PBS, with 0.01% BSA (pH 7.4). Duplicate samples of 100uL were then transferred to EMMPRIN-coated microtiter wells and incubated for 2h at 37 degree C. Wells were washed with PBST and incubated for 1h with anti-IGF2 pAb, then aspirated and washed 3 times. After incubation with HRP labelled secondary antibody, wells were aspirated and washed 3 times. With the addition of substrate solution, wells were incubated 15-25 minutes at 37 degree C. Finally, add 50uL stop solution to the wells and read at 450nm immediately. The binding activity of IGF2 and EMMPRIN was shown in Figure 1, and this effect was in a dose dependent manner.)

Insulin Like Growth Factor 2 (IGF2), Active Protein (Cat# AAA2105064)

Full Name
Active Insulin Like Growth Factor 2 (IGF2)
Gene Names
IGF2; GRDF; IGF-II; PP9974; C11orf43
Applications
Cell Culture, Activity Assays
Purity
> 90%
Pricing
$160/0.01 mg | $290/0.05 mg | $445/0.1 mg | $540/0.2 mg | $1,045/0.5 mg | $1,535/1 mg | $3,765/5 mg
Activity Data (Figure. The binding activity of IGFBP3 with EGFR.Insulin-like growth factor-binding protein 3, also known as IGFBP3 is one of six IGF binding proteins (IGFBP1 to IGFBP6) that have highly conserved structures and bind the insulin-like growth factors IGF-1 and IGF-2 with high affinity. Within tissues, IGFBP3 can bind IGF1 and IGF2 released by many cell types, and block their access to the IGF-1 receptor (IGF1R), which is activated by both IGFs. IGFBP3 also interacts with cell-surface proteins, affecting cell signaling from outside the cell or after internalization, and also enters the cell nucleus where it binds to nuclear hormone receptors and other ligands. Besides, Epidermal Growth Factor Receptor (EGFR) has been identified as an interactor of IGFBP3, thus a binding ELISA assay was conducted to detect the interaction of recombinant human IGFBP3 and recombinant human EGFR. Briefly, IGFBP3 were diluted serially in PBS, with 0.01% BSA (pH 7.4). Duplicate samples of 100uL were then transferred to EGFR-coated microtiter wells and incubated for 2h at 37 degree C. Wells were washed with PBST and incubated for 1h with anti-IGFBP3 pAb, then aspirated and washed 3 times. After incubation with HRP labelled secondary antibody, wells were aspirated and washed 3 times. With the addition of substrate solution, wells were incubated 15-25 minutes at 37 degree C. Finally, add 50uL stop solution to the wells and read at 450nm immediately. The binding activity of IGFBP3 and EGFR was shown in Figure 1, and this effect was in a dose dependent manner.)

Insulin Like Growth Factor Binding Protein 3 (IGFBP3), Active Protein (Cat# AAA2105066)

Full Name
Active Insulin Like Growth Factor Binding Protein 3 (IGFBP3)
Gene Names
IGFBP3; IBP3; BP-53
Applications
Cell Culture, Activity Assays
Purity
> 90%
Pricing
$180/0.01 mg | $345/0.05 mg | $530/0.1 mg | $650/0.2 mg | $1,260/0.5 mg | $1,870/1 mg | $4,595/5 mg
Dot Blot (DB) (Dot blot analysis of anti-AKT1-pS473 Phospho-specific Pab on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.5ug per ml.)

Phospho-AKT1 (S473), Polyclonal Antibody (Cat# AAA9208927)

Full Name
Phospho-AKT1 (S473) Antibody
Gene Names
AKT1; AKT; PKB; RAC; CWS6; PRKBA; PKB-ALPHA; RAC-ALPHA
Reactivity
Human
Applications
WB, DB, EIA
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Pricing
$435/0.4 mL | $190/0.08 mL | $1,705/5x0.4 mL
Immunohistochemistry (IHC)

SOCS1, Polyclonal Antibody (Cat# AAA540117)

Full Name
SOCS1 Antibody
Reactivity
Human, Monkey, Mouse, Rat
Applications
EIA, IHC, IP, WB
Pricing
$445/0.1 mg | $1,855/5x0.1 mg

AKT1 (S129), Blocking Peptide (Cat# AAA9224985)

Full Name
Phospho-AKT1(S129) Antibody Blocking peptide
Gene Names
AKT1; AKT; PKB; RAC; CWS6; PRKBA; PKB-ALPHA; RAC-ALPHA

transmembrane protein 219, ELISA Kit (Cat# AAA9335105)

Full Name
Mouse Transmembrane protein 219, TMEM219 ELISA Kit
Gene Names
Tmem219; IGFBP-3R; 1110032O16Rik; 2900045G02Rik
Reactivity
Mouse
Pricing
$540/48-Strip-Wells | $755/96-Strip-Wells | $3,410/5x96-Strip-Wells | $6,715/10x96-Strip-Wells

Transmembrane protein 219 (TMEM219), Recombinant Protein (Cat# AAA1383417)

Full Name
Recombinant Human Transmembrane protein 219 (TMEM219), partial
Gene Names
TMEM219; IGFBP-3R
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Pricing
$1,915/1 mg (E-Coli) | $510/0.1 mg (E-Coli) | $310/0.02 mg (E-Coli) | $8,395/5x1 mg (E-Coli)

transmembrane protein 219, ELISA Kit (Cat# AAA9330640)

Full Name
Bovine Transmembrane protein 219, TMEM219 ELISA Kit
Gene Names
TMEM219; IGFBP-3R
Reactivity
Bovine
Pricing
$540/48-Strip-Wells | $755/96-Strip-Wells | $3,410/5x96-Strip-Wells | $6,715/10x96-Strip-Wells
Western Blot (WB) ()

IRS2, Monoclonal Antibody (Cat# AAA838125)

Full Name
IRS2 antibody
Gene Names
IRS2; IRS-2
Applications
EIA, WB
Purity
IRS2 antibody was purified by ammonium sulfate precipitation

Transmembrane protein 219 (Tmem219), Recombinant Protein (Cat# AAA1310386)

Full Name
Recombinant Mouse Transmembrane protein 219 (Tmem219), partial
Gene Names
Tmem219; IGFBP-3R; 1110032O16Rik; 2900045G02Rik
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Pricing
$1,500/1 mg (E-Coli) | $2,015/1 mg (Yeast) | $1,500/0.1 mg (Baculovirus) | $2,015/0.1 mg (Mammalian-Cell) | $1,045/0.5 mg (E-Coli) | $1,265/0.5 mg (Yeast) | $1,045/0.05 mg (Baculovirus) | $1,265/0.05 mg (Mammalian-Cell)

Transmembrane protein 219 (TMEM219), Recombinant Protein (Cat# AAA1412185)

Full Name
Recombinant Bovine Transmembrane protein 219 (TMEM219), partial
Gene Names
TMEM219; IGFBP-3R
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Pricing
$1,505/1 mg (E-Coli) | $2,020/1 mg (Yeast) | $1,505/0.1 mg (Baculovirus) | $2,020/0.1 mg (Mammalian-Cell) | $1,045/0.5 mg (E-Coli) | $1,265/0.5 mg (Yeast) | $1,045/0.05 mg (Baculovirus) | $1,265/0.05 mg (Mammalian-Cell)

SOCS1, Polyclonal Antibody (Cat# AAA544935)

Full Name
SOCS1 Antibody BIOTIN-Conjugated
Reactivity
Human, Monkey, Mouse, Rat
Applications
EIA, IHC, IP, WB
Pricing
$560/0.1 mg | $2,380/5x0.1 mg

SOCS1, Polyclonal Antibody (Cat# AAA544936)

Full Name
SOCS1 Antibody FITC-Conjugated
Reactivity
Human, Monkey, Mouse, Rat
Applications
EIA, IHC, IP, WB
Pricing
$560/0.1 mg | $2,380/5x0.1 mg

SOCS1, Positive Control (Cat# AAA543273)

Full Name
SOCS1 Positive Control
Applications
WB
Pricing
$335/5 Applications | $1,350/5x5 Applications

TMEM219, siRNA (Cat# AAA8203041)

Full Name
TMEM219 siRNA (Mouse)
Gene Names
Tmem219; IGFBP-3R; 1110032O16Rik; 2900045G02Rik
Reactivity
Mouse
Applications
RNAi
Purity
> 97%
Pricing
$395/15 nmol | $555/30 nmol | $2,440/5x30 nmol

SOCS1, Blocking Peptide (Cat# AAA544497)

Full Name
SOCS1 Peptide
Applications
Immunocompetition, Immunodepletion
Pricing
$280/0.25 mg | $1,110/5x0.25 mg

Transmembrane Protein 219 (TMEM219), ELISA Kit (Cat# AAA9371079)

Full Name
Plant Transmembrane Protein 219 (TMEM219) ELISA Kit
Reactivity
Plant

TMEM219, siRNA (Cat# AAA8228532)

Full Name
TMEM219 siRNA (Human)
Gene Names
TMEM219; IGFBP-3R
Reactivity
Human
Applications
RNAi
Purity
> 97%
Pricing
$395/15 nmol | $555/30 nmol | $2,440/5x30 nmol
Western Blot (WB) (Western blot analysis of extracts from 293 Insulin, using Phospho-IGF-I Receptor (Tyr1131) /Insulin Receptor (Tyr1146)[Tyr1161] Antibody. Lane1 was treated with phospho-blocking peptide, Lane2 was treated with non-phospho-blocking peptide.)

IGF1 Receptor, Polyclonal Antibody (Cat# AAA9613198)

Full Name
Phospho-IGF1 Receptor (Tyr1131/Tyr1146) Antibody
Gene Names
IGF1R; IGFR; CD221; IGFIR; JTK13
Reactivity
Human, Mouse, Rat, Pig
Applications
WB, EIA
Purity
Peptide affinity purification
Pricing
$245/0.05 mL | $310/0.1 mL | $370/0.2 mL | $1,605/5x0.2 mL
Western Blot (WB) (Western blot analysis of extracts from Mouse brain, using Phospho-IGF1 Receptor (Tyr980) Antibody. The lane on the left was treated with blocking peptide.)

IGF1 Receptor, Polyclonal Antibody (Cat# AAA9614119)

Full Name
Phospho-IGF1 Receptor (Tyr980) Antibody
Gene Names
IGF1R; IGFR; CD221; IGFIR; JTK13
Reactivity
Human, Mouse
Predicted Reactivity: Bovine (100%), Rabbit (100%), Dog (100%), Chicken (92%), Xenopus (92%)
Applications
WB, IHC, IF, ICC, EIA
Purity
The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho-peptide and non-phospho-peptide affinity columns.
Pricing
$245/0.05 mL | $310/0.1 mL | $370/0.2 mL | $1,605/5x0.2 mL
Western Blot (WB) (Western blot analysis FLT3 (Phospho-Tyr589) using Insulin treated 293 whole cell lysates.-/+ means absence or presence of N peptide(non-phospho peptide) and P peptide(phospho peptide).)

Flt3/CD135, Polyclonal Antibody (Cat# AAA9614154)

Full Name
Phospho-Flt3/CD135 (Tyr589) Antibody
Gene Names
FLT3; FLK2; STK1; CD135; FLK-2
Reactivity
Human, Mouse, Monkey
Predicted Reactivity: Pig (80%), Bovine (80%), Horse (90%), Sheep (100%), Rabbit (90%), Dog (90%), Chicken (90%)
Applications
WB, IF, ICC, EIA
Purity
The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho-peptide and non-phospho-peptide affinity columns.
Pricing
$245/0.05 mL | $310/0.1 mL | $370/0.2 mL | $1,605/5x0.2 mL

IGFBP3 / Insulin-Like Growth Factor-Binding Protein 3, Recombinant Protein (Cat# AAA2901573)

Full Name
Human IGFBP3 / Insulin-Like Growth Factor-Binding Protein 3 Recombinant Protein
Gene Names
IGFBP3; IBP3; BP-53
Applications
EIA, WB, AP
Purity
>95% by SDS-PAGE

IGF1R / Insulin-Like Growth Factor 1 Receptor, Recombinant Protein (Cat# AAA2902290)

Full Name
Human IGF1R / Insulin-Like Growth Factor 1 Receptor Recombinant Protein
Gene Names
IGF1R; IGFR; CD221; IGFIR; JTK13
Applications
EIA, WB, AP
Purity
>95% by SDS-PAGE
Western Blot (WB) (Western blot analysis of IGF-I Receptor/Insulin Receptor in lysates of 293, using IGF-I Receptor/Insulin Receptor Antibody(AF4697).)

IGF1 Receptor, Polyclonal Antibody (Cat# AAA9613405)

Full Name
IGF1 Receptor Antibody
Gene Names
IGF1R; IGFR; CD221; IGFIR; JTK13
Reactivity
Human, Mouse, Rat, Pig
Predicted Reactivity: Bovine (100%), Rabbit (100%), Dog (100%), Chicken (100%), Xenopus (100%)
Applications
WB, EIA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin
Pricing
$245/0.05 mL | $305/0.1 mL | $365/0.2 mL | $1,495/5x0.2 mL

F2RL2, Polyclonal Antibody (Cat# AAA9448233)

Full Name
F2RL2 Conjugated Antibody
Gene Names
PAPPA; PAPA; DIPLA1; PAPP-A; PAPPA1; ASBABP2; IGFBP-4ase
Reactivity
Human
Applications
Most Applications
Pricing
$480/0.1 mL (Biotin) | $480/0.1 mL (AF350) | $480/0.1 mL (AF405) | $480/0.1 mL (AF488) | $480/0.1 mL (AF555) | $480/0.1 mL (AF594) | $480/0.1 mL (AF647) | $480/0.1 mL (AF680) | $480/0.1 mL (AF750)

TMEM219, Polyclonal Antibody (Cat# AAA7142382)

Full Name
Rabbit anti-Homo sapiens (Human) TMEM219 Polyclonal Antibody
Gene Names
TMEM219; IGFBP-3R
Reactivity
Homo sapiens (Human)
Applications
EIA, Western Blot, ensure identification of antigen
Purity
Protein A/G
Western Blot (WB) (Western blot analysis of extracts from HepG2, using HER4 (Phospho-Tyr1242) Antibody.)

HER4, Polyclonal Antibody (Cat# AAA9614436)

Full Name
Phospho-HER4 (Tyr1242) Antibody
Gene Names
ERBB4; HER4; p180erbB4
Reactivity
Human, Mouse, Rat
Predicted Reactivity: Horse (100%), Sheep (100%), Rabbit (100%), Dog (100%), Chicken (100%), Xenopus (88%)
Applications
WB, IF, ICC, EIA
Purity
The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho-peptide and non-phospho-peptide affinity columns.
Pricing
$245/0.05 mL | $310/0.1 mL | $370/0.2 mL | $1,605/5x0.2 mL
Western Blot (WB) (Western blot detection of Phospho-AKT (Ser473) in C6,3T3,Hela cell lysates using Phospho-AKT (Ser473) Rabbit mAb(1:1000 diluted).Predicted band size:56kDa.Observed band size:56kDa.)

AKT, Monoclonal Antibody (Cat# AAA4754090)

Full Name
Phospho-AKT (Ser473) Rabbit mAb
Gene Names
AKT1; AKT; PKB; RAC; CWS6; PRKBA; PKB-ALPHA; RAC-ALPHA
Reactivity
Human, Mouse, Rat
Applications
WB, IHC-P, IHC-F, ICC, IF
Purity
Affinity purified
Pricing
$440/0.1 mL | $1,530/5x0.1 mL

SH2B adapter protein 1 (SH2B1), Recombinant Protein (Cat# AAA9018615)

Full Name
Recombinant Human SH2B adapter protein 1 (SH2B1)(T484A,V541A), partial
Gene Names
SH2B1; PSM; SH2B
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Pricing
$1,915/1 mg (E-Coli) | $510/0.1 mg (E-Coli) | $310/0.02 mg (E-Coli) | $8,395/5x1 mg (E-Coli)
Typical Testing Data/Standard Curve (for reference only)

Tumor Necrosis Factor Receptor Superfamily, Member 4 (TNFRSF4), ELISA Kit (Cat# AAA2709655)

Full Name
Human Tumor Necrosis Factor Receptor Superfamily, Member 4 (TNFRSF4)(Sandwich ELISA) ELISA Kit
Reactivity
Human
Applications
EIA
Pricing
$310/48-Strip-Wells | $385/96-Strip-Wells | $1,545/5x96-Strip-Wells | $2,970/10x96-Strip-Wells | $235/24-Strip-Wells
Typical Testing Data/Standard Curve (for reference only)

Tumor Necrosis Factor Receptor Superfamily, Member 4 (TNFRSF4), ELISA Kit (Cat# AAA2125246)

Full Name
Human Tumor Necrosis Factor Receptor Superfamily, Member 4 (TNFRSF4)(Sandwich ELISA) ELISA Kit
Reactivity
Human
Applications
EIA
Pricing
$510/48-Strip-Wells | $685/96-Strip-Wells | $2,745/5x96-Strip-Wells | $5,005/10x96-Strip-Wells | $340/24-Strip-Wells
Western Blot (WB) (Western blot analysis of HER4 (Phospho-Tyr1056) using Insulin treated HeLa whole cell lysates.-/+ means absence or presence of N peptide(non-phospho peptide) and P peptide(phospho peptide).)

HER4, Polyclonal Antibody (Cat# AAA9614370)

Full Name
Phospho-HER4 (Tyr1056) Antibody
Gene Names
ERBB4; HER4; p180erbB4
Reactivity
Human, Mouse, Rat
Predicted Reactivity: Pig (100%), Sheep (100%), Rabbit (100%), Dog (100%)
Applications
WB, IF, ICC, EIA
Purity
The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho-peptide and non-phospho-peptide affinity columns.
Pricing
$245/0.05 mL | $310/0.1 mL | $370/0.2 mL | $1,605/5x0.2 mL

CCN3, Polyclonal Antibody (Cat# AAA9629197)

Full Name
CCN3 Antibody
Gene Names
NOV; CCN3; NOVh; IBP-9; IGFBP9; IGFBP-9
Reactivity
Human, Mouse, Rat
Applications
EIA, peptide
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Pricing
$260/0.1 mL | $305/0.2 mL | $1,220/5x0.2 mL

BAT3, Polyclonal Antibody (Cat# AAA9629216)

Full Name
BAT3 Antibody
Gene Names
BAG6; G3; BAT3; BAG-6; D6S52E
Reactivity
Human, Mouse, Rat
Applications
EIA, peptide
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Pricing
$260/0.1 mL | $305/0.2 mL | $1,220/5x0.2 mL
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