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257 results for "c Met inhibitor" - showing 1-50
Chemical Structure
Foretinib (GSK1363089, XL880), Inhibitor (Cat# AAA384812)
Full Name
Foretinib (GSK1363089, XL880)
Purity
>98%
Pricing
$125/5 mg | $200/25 mg | $300/50 mg | $465/100 mg | $150/1 mL (in DMSO) | $2,050/5x100 mg
Western Blot (WB)
(WB Analysis. HeLa whole cell lysate.)
14-3-3, gamma, Monoclonal Antibody (Cat# AAA632711)
Full Name
14-3-3, gamma (Protein Kinase C Inhibitor Protein 1, KCIP-1, Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase Activation Protein, gamma Polypeptide, YWHAG)
Gene Names
YWHAG; 14-3-3GAMMA
Reactivity
Bovine, Chicken, Human, Mouse, Rat0
Applications
WB
Purity
Ascites
Ascites.
Ascites.
Pricing
$655/0.1 mL | $2,940/5x0.1 mL
Western Blot (WB)
(Western Blot: 14-3-3 gamma detected in lysates using MBS632857 Lane 1: HeLa cell lysate,|Lanes 2 & 3: bengamide treated lysates (8h and 24h, respectively).)
14-3-3, gamma, Monoclonal Antibody (Cat# AAA632857)
Full Name
14-3-3, gamma (Protein kinase C inhibitor protein 1, KCIP-1, Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide, YWHAG)
Gene Names
YWHAG; 14-3-3GAMMA
Reactivity
Human
Applications
WB
Purity
Ascites
Ascites
Ascites
Pricing
$610/0.1 mL | $2,730/5x0.1 mL
14-3-3, gamma, Monoclonal Antibody (Cat# AAA631763)
Full Name
14-3-3, gamma (Protein kinase C inhibitor protein 1, KCIP-1, Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide, YWHAG)
Gene Names
YWHAG; 14-3-3GAMMA
Reactivity
Human
Applications
WB
Purity
Ascites
Mouse ascites
Mouse ascites
Pricing
$580/0.1 mL | $2,595/5x0.1 mL
Testing Data
(Image: WB Analysis. HeLa whole cell lysate. Lanes 2 and 3: bengamide treated lysates (8h and 24h, respectively).)
14-3-3 gamma [KC21], Antibody (Cat# AAA555021)
Full Name
Mouse Monoclonal Anti-14-3-3 gamma [KC21]
Gene Names
YWHAG; PPP1R170; 14-3-3GAMMA
Reactivity
Human
Applications
WB
Pricing
$425/0.1 mL | $1,760/5x0.1 mL
SDS-PAGE
14-3-3 beta / YWHAB, Recombinant Protein (Cat# AAA2546049)
Full Name
Recombinant Human 14-3-3 beta / YWHAB Protein
Gene Names
YWHAB; HS1; GW128; YWHAA; KCIP-1; HEL-S-1
Purity
> 93 % as determined by SDS-PAGE
Pricing
$440/0.05 mg | $675/0.1 mg | $3,030/5x0.1 mg
Structure
MGCD-265, Inhibitor (Cat# AAA578901)
Full Name
MGCD-265
Purity
98.1%
Pricing
$215/2 mg | $250/5 mg | $335/10 mg | $520/25 mg | $775/50 mg | $275/1 mL (in DMSO) | $3,210/5x50 mg
Structure
Baricitinib, Inhibitor (Cat# AAA576162)
Full Name
Baricitinib (LY3009104, INCB028050)
Purity
99.8%
Pricing
$175/1 mg | $185/2 mg | $210/5 mg | $215/10 mg | $240/25 mg | $260/50 mg | $285/100 mg | $325/200 mg | $215/1 mL (in DMSO) | $1,185/5x200 mg
14-3-3 beta / YWHAB, Recombinant Protein (Cat# AAA2546050)
Full Name
Recombinant Human 14-3-3 beta / YWHAB Protein (GST tag)
Gene Names
YWHAB; HS1; GW128; YWHAA; KCIP-1; HEL-S-1
Purity
> 96 % as determined by SDS-PAGE
Pricing
$440/0.05 mg | $675/0.1 mg | $3,030/5x0.1 mg
Protein Kinase C, eta Inhibitor, Pseudosubstrate, Inhibitor (Cat# AAA655411)
Full Name
Protein Kinase C, eta Inhibitor, Pseudosubstrate
Purity
Highly Purified
~80% by HPLC analysis (purity based on peak area)
~80% by HPLC analysis (purity based on peak area)
Pricing
$325/1 mg | $1,460/5x1 mg
Testing Data
(specific activity)
c-Met, Active Protein (Cat# AAA637531)
Full Name
c-Met, Recombinant, Human (Hepatocyte Growth Factor, Scatter Factor Receptor, HGF, SF)
Gene Names
MET; c-Met
Purity
Highly Purified
~ 60%
~ 60%
Pricing
$675/0.01 mg | $3,040/5x0.01 mg
Testing Data
(Foretinib (GSK1363089, XL880) is a novel MET and VEGFR2/KDR kinases inhibitor with an IC50 of 0.4 and 0.8 nM for MET and KDR, respectively. Foretinib (GSK1363089, XL880) inhibits HGF receptor family tyrosine kinases with an IC50 of 3 nM for Ron. Foretinib (GSK1363089, XL880) also inhibits KDR, Flt-1, and Flt-4 with IC50 of 0.9, 6.8 and 2.8 nM, respectively. In addition, EXEL-2880 inhibits members of the platelet-derived growth factor receptor family and the angiopoietin-1 receptor Tie-2. Foretinib (GSK1363089, XL880) exhibits modest activity against fibroblast growth factor receptor 1 and epidermal growth factor receptor and is inactive against 50 serine/threonine kinases, including cyclin-dependent kinases and protein kinase C isoforms. To delineate the cellular effect of foretinib (GSK1363089, XL880), VEGF- induced extracellular signal-regulated kinase phosphorylation was used to assess the effect of the compound on phosphorylation of KDR in human umbilical vein endothelial cells that resulted in an IC50 of 16 nM. Foretinib(GSK1363089, XL880) is the 1st orally available small molecule inhibitor of Met to enter the clinic and appears to be generally well tolerated. Anti-tumor activity has been observed and Foretinib may represent an active treatment option for patients with papillary renal-cell carcinoma. [1])
Foretinib, Inhibitor (Cat# AAA8506342)
Full Name
Foretinib (GSK1363089, XL880)
Purity
>99%
Pricing
$440/5 mg | $1,940/5x5 mg
Protein Kinase C, eta Inhibitor, Pseudosubstrate, Myristoylated, Inhibitor (Cat# AAA655428)
Full Name
Protein Kinase C, eta Inhibitor, Pseudosubstrate, Myristoylated
Purity
Highly Purified
~90% by HPLC and MS analysis
~90% by HPLC and MS analysis
Pricing
$325/1 mg | $1,460/5x1 mg
Structure
MK-2461, Inhibitor (Cat# AAA578667)
Full Name
MK-2461
Purity
98.4%
Pricing
$205/1 mg | $225/2 mg | $285/5 mg | $375/10 mg | $640/25 mg | $1,030/50 mg | $1,695/100 mg | $295/1 mL (in DMSO) | $7,365/5x100 mg
Structure
SGI-1027, Inhibitor (Cat# AAA577339)
Full Name
SGI-1027
Purity
99.45%
Pricing
$205/5 mg | $235/10 mg | $300/25 mg | $425/50 mg | $640/100 mg | $225/1 mL (in DMSO) | $2,605/5x100 mg
SerpinB8 , Monoclonal Antibody (Cat# AAA2544518)
Full Name
Rabbit anti Mouse SerpinB8 Monoclonal Antibody
Gene Names
SERPINB8; PI8; CAP2; PSS5
Reactivity
Mouse
Applications
EIA
Pricing
$540/0.2 mL | $360/0.12 mL | $240/0.06 mL
Structure
PHA-665752, Inhibitor (Cat# AAA578696)
Full Name
PHA-665752
Purity
99.4%
Pricing
$205/5 mg | $230/10 mg | $315/25 mg | $455/50 mg | $705/100 mg | $975/200 mg | $230/1 mL (in DMSO) | $4,125/5x200 mg
Structure
AMG-900, Inhibitor (Cat# AAA578928)
Full Name
AMG-900
Purity
98.0%
Pricing
$210/2 mg | $255/5 mg | $325/10 mg | $510/25 mg | $730/50 mg | $265/1 mL (in DMSO) | $3,025/5x50 mg
Hepatitis Virus C NS3 Protease Inhibitor 1, Peptide (Cat# AAA8246594)
Full Name
Hepatitis Virus C NS3 Protease Inhibitor 1
Purity
> 95%
Pricing
$215/1 mg | $390/5 mg | $550/10 mg | $2,425/5x10 mg
Structure
SU11274, Inhibitor (Cat# AAA578719)
Full Name
SU11274
Purity
98.6%
Pricing
$205/2 mg | $240/5 mg | $290/10 mg | $430/25 mg | $700/50 mg | $855/100 mg | $290/1 mL (in DMSO) | $3,575/5x100 mg
Structure
Foretinib, Inhibitor (Cat# AAA578171)
Full Name
Foretinib
Purity
99.80%
Pricing
$205/5 mg | $215/10 mg | $270/25 mg | $340/50 mg | $485/100 mg | $215/1 mL (in DMSO) | $1,920/5x100 mg
Chemical Structure
Capmatinib 2HCl, Inhibitor (Cat# AAA5750411)
Full Name
Capmatinib 2HCl
Purity
99.8%
Pricing
$195/2 mg | $210/5 mg | $225/10 mg | $385/50 mg | $565/100 mg | $775/200 mg | $3,225/5x200 mg
Structure
DCC-2618, Inhibitor (Cat# AAA5750109)
Full Name
DCC-2618
Purity
98.7%
Pricing
$210/2 mg | $245/5 mg | $295/10 mg | $470/25 mg | $785/50 mg | $1,180/100 mg | $245/1 mL (in DMSO) | $5,040/5x100 mg
SDS-PAGE
RTN4 / NOGO-A, Recombinant Protein (Cat# AAA2545429)
Full Name
Recombinant Human RTN4 / NOGO-A Protein (GST tag)
Gene Names
RTN4; ASY; NSP; NOGO; RTN-X; NSP-CL; RTN4-A; RTN4-C; RTN4-B1; RTN4-B2; NI220/250; Nbla00271; Nbla10545
Purity
> 92 % as determined by SDS-PAGE
Pricing
$440/0.05 mg | $675/0.1 mg | $3,030/5x0.1 mg
Structure
Golvatinib, Inhibitor (Cat# AAA579058)
Full Name
Golvatinib (E7050)
Purity
98.24%
Pricing
$175/1 mg | $185/2 mg | $210/5 mg | $235/10 mg | $295/25 mg | $330/50 mg | $480/100 mg | $230/1 mL (in DMSO) | $1,900/5x100 mg
S49076, Inhibitor (Cat# AAA578326)
Full Name
S49076
Purity
98.0%
Pricing
$210/2 mg | $240/5 mg | $265/10 mg | $375/25 mg | $545/50 mg | $905/100 mg | $240/1 mL (in DMSO) | $3,810/5x100 mg
S49076, Inhibitor (Cat# AAA579641)
Full Name
S49076 HCl
Purity
98.0%
Pricing
$200/1 mg | $230/2 mg | $255/5 mg | $320/10 mg | $425/25 mg | $605/50 mg | $980/100 mg | $4,130/5x100 mg
Structure
AMG-208, Inhibitor (Cat# AAA578823)
Full Name
AMG-208
Purity
99.12%
Pricing
$205/2 mg | $245/5 mg | $295/10 mg | $485/25 mg | $595/50 mg | $2,405/5x50 mg
Structure
Tivantinib, Inhibitor (Cat# AAA578686)
Full Name
Tivantinib (ARQ 197)
Purity
99.4%
Pricing
$200/5 mg | $215/10 mg | $275/25 mg | $355/50 mg | $510/100 mg | $750/200 mg | $205/1 mL (in DMSO) | $3,100/5x200 mg
Structure
JNJ-38877605, Inhibitor (Cat# AAA578668)
Full Name
JNJ-38877605
Purity
97.15%
Pricing
$185/2 mg | $205/5 mg | $230/10 mg | $290/25 mg | $365/50 mg | $520/100 mg | $205/1 mL (in DMSO) | $2,060/5x100 mg
Chemical Structure
(Chemical structure of PHA 665752 (SIH-421), a MET kinase inhibitor. CAS #: 477575-56-7. Molecular Formula: C32H34Cl2N4O4S. Molecular Weight: 641.61 g/mol.)
PHA 665752, Small Molecule (Cat# AAA808123)
Full Name
PHA 665752
Purity
>98
Pricing
$240/5 mg | $610/25 mg | $2,520/5x25 mg | $870/5x5 mg
Structure
AMG-458, Inhibitor (Cat# AAA578926)
Full Name
AMG-458
Purity
98.0%
Pricing
$210/1 mg | $245/2 mg | $350/5 mg | $430/10 mg | $715/25 mg | $430/1mL*10mM (in DMSO) | $2,935/5x25 mg
CP-724714, Inhibitor (Cat# AAA579919)
Full Name
CP-724714
Purity
98.82%
Pricing
$205/2 mg | $235/5 mg | $295/10 mg | $430/25 mg | $595/50 mg | $835/100 mg | $235/1 mL (in DMSO) | $3,495/5x100 mg
LY2801653, Inhibitor (Cat# AAA579586)
Full Name
LY2801653
Purity
99.56%
Pricing
$215/2 mg | $245/5 mg | $295/10 mg | $480/25 mg | $595/50 mg | $785/100 mg | $275/1 mL (in DMSO) | $3,260/5x100 mg
SDS-Page
Tumor Necrosis Factor Receptor II, Active Protein (Cat# AAA2556793)
Full Name
Recombinant Mouse Tumor Necrosis Factor Receptor II Protein
Gene Names
Tnfrsf1b; p75; TNFBR; Tnfr2; CD120b; TNF-R2; TNFR80; TNFRII; Tnfr-1; TNF-R75; TNF-R-II; TNF-alphaR2; TNFalpha-R2
Purity
>95% as determined by reducing SDS-PAGE.
Pricing
$160/0.01 mg | $295/0.05 mg | $1,320/5x0.05 mg
SDS-Page
Serpin A11, Recombinant Protein (Cat# AAA8122740)
Full Name
Serpin A11 Protein, Mouse, Recombinant (His Tag)
Gene Names
Serpina11; Gm895
Purity
>94% as determined by SDS-PAGE
Pricing
$395/0.1 mg | $1,635/5x0.1 mg
Structure
c-Met 1, Inhibitor (Cat# AAA5752843)
Full Name
c-Met inhibitor 1
Purity
99.56%
Pricing
$325/5 mg | $380/10 mg | $805/50 mg | $1,270/100 mg | $340/1 mL (in DMSO) | $5,440/5x100 mg
Structure
Tyr-Gly-Gly-Phe-Met-OH, Inhibitor (Cat# AAA5752414)
Full Name
Tyr-Gly-Gly-Phe-Met-OH
Purity
98.00%
Pricing
$195/10 mg | $230/25 mg | $290/50 mg | $365/100 mg | $205/1 mL (in DMSO) | $1,375/5x100 mg
SDS-Page
Carboxypeptidase B2, Recombinant Protein (Cat# AAA8123061)
Full Name
Carboxypeptidase B2 Protein, Mouse, Recombinant (His Tag)
Gene Names
Cpb2; CPR; Cpu; TAFI; AI255929; 1110032P04Rik; 4930405E17Rik
Purity
>97% as determined by SDS-PAGE
Pricing
$395/0.1 mg | $1,635/5x0.1 mg
SDS-Page
14-3-3 epsilon, Recombinant Protein (Cat# AAA8120516)
Full Name
14-3-3 epsilon Protein, Human, Recombinant
Gene Names
YWHAE; MDS; MDCR; KCIP-1; 14-3-3E
Purity
>96% as determined by SDS-PAGE
Pricing
$450/0.1 mg | $1,885/5x0.1 mg
SDS-Page
Alpha 2 Antiplasmin/SerpinF2, Active Protein (Cat# AAA8122578)
Full Name
Alpha 2 Antiplasmin/SerpinF2 Protein, Mouse, Recombinant (His Tag)
Gene Names
Serpinf2; Pli; AI747498; Serpimf2
Purity
>97% as determined by SDS-PAGE
Pricing
$395/0.05 mg | $1,635/5x0.05 mg
SDS-Page
Semaphorin 5A, Recombinant Protein (Cat# AAA8120779)
Full Name
Semaphorin 5A Protein, Human, Recombinant (hFc Tag)
Gene Names
SEMA5A; semF; SEMAF
Purity
>90% as determined by SDS-PAGE
Pricing
$395/0.05 mg | $1,635/5x0.05 mg
SDS-Page
SerpinI2, Recombinant Protein (Cat# AAA8120626)
Full Name
SerpinI2 Protein, Human, Recombinant (His Tag)
Gene Names
SERPINI2; MEPI; PI14; PANCPIN; TSA2004
Purity
>90% as determined by SDS-PAGE
Pricing
$450/0.1 mg | $1,885/5x0.1 mg
SDS-Page
Semaphorin 5A, Recombinant Protein (Cat# AAA8120780)
Full Name
Semaphorin 5A Protein, Human, Recombinant (His Tag)
Gene Names
SEMA5A; semF; SEMAF
Purity
>90% as determined by SDS-PAGE
Pricing
$395/0.05 mg | $3,205/1 mg | $14,270/5x1 mg
SDS-Page
Cortisol Binding Globulin, Recombinant Protein (Cat# AAA8122677)
Full Name
Cortisol Binding Globulin Protein, Mouse, Recombinant (His Tag)
Gene Names
Serpina6; Cbg
Purity
>98% as determined by SDS-PAGE
Pricing
$395/0.1 mg | $1,635/5x0.1 mg
SDS-Page
TFPI2, Recombinant Protein (Cat# AAA8123089)
Full Name
TFPI2 Protein, Mouse, Recombinant (His Tag)
Gene Names
Tfpi2; AV000670; PP5/TFPI-2
Purity
>95% as determined by SDS-PAGE
Pricing
$450/0.1 mg | $1,885/5x0.1 mg
SDS-Page
HE4, Recombinant Protein (Cat# AAA8121200)
Full Name
HE4 Protein, Human, Recombinant (His Tag)
Purity
>95% as determined by SDS-PAGE
Pricing
$395/0.1 mg | $2,175/1 mg | $9,625/5x1 mg
SDS-Page
SerpinA10, Recombinant Protein (Cat# AAA8122678)
Full Name
SerpinA10 Protein, Mouse, Recombinant (His Tag)
Gene Names
Serpina10; PZI; ZPI
Purity
>95% as determined by SDS-PAGE
Pricing
$450/0.1 mg | $1,885/5x0.1 mg
Int-H1-S6A F8, Peptide (Cat# AAA566496)
Full Name
Int-H1-S6A F8 c-myc Inhibitor
Purity
>=95% (HPLC)
Pricing
$295/0.5 mg | $1,260/5x0.5 mg
SDS-Page
Serpinb6b, Recombinant Protein (Cat# AAA8122710)
Full Name
Serpinb6b Protein, Mouse, Recombinant (His Tag)
Gene Names
Serpinb6b; NK13; Spi12; ovalbumin
Purity
>92% as determined by SDS-PAGE
Pricing
$395/0.05 mg | $1,635/5x0.05 mg
