Testing Data
(Image: WB Analysis. HeLa whole cell lysate. Lanes 2 and 3: bengamide treated lysates (8h and 24h, respectively).)
anti-Human 14-3-3 gamma [KC21] Antibody | anti-YWHAG antibody
Mouse Monoclonal Anti-14-3-3 gamma [KC21]
Testing Data
(Image: WB Analysis. HeLa whole cell lysate. Lanes 2 and 3: bengamide treated lysates (8h and 24h, respectively).)
Testing Data
(Image: WB Analysis. HeLa whole cell lysate. Lanes 2 and 3: bengamide treated lysates (8h and 24h, respectively).)
NCBI and Uniprot Product Information
Uniprot Description
14-3-3 gamma: Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Homodimer. Interacts with SAMSN1. Interacts with RAF1, SSH1 and CRTC2/TORC2. Interacts with ABL1 (phosphorylated form); the interaction retains it in the cytoplasm. Interacts with GAB2. Interacts with MDM4 (phosphorylated); negatively regulates MDM4 activity toward TP53. Interacts with PKA-phosphorylated AANAT. Highly expressed in brain, skeletal muscle, and heart. Belongs to the 14-3-3 family.
Protein type: Adaptor/scaffold
Chromosomal Location of Human Ortholog: 7q11.23
Cellular Component: cytoplasmic vesicle membrane; cytosol; focal adhesion; membrane
Molecular Function: insulin-like growth factor receptor binding; protein binding; protein kinase C binding
Biological Process: G2/M transition of mitotic cell cycle; regulation of neuron differentiation; regulation of synaptic plasticity
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Product Notes
The YWHAG ywhag (Catalog #AAA555021) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The Mouse Monoclonal Anti-14-3-3 gamma [KC21] reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's 14-3-3 gamma [KC21] can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the YWHAG ywhag for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "14-3-3 gamma [KC21], Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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