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37 results for " PI3K Inhibitors" - showing 1-37
HIF1 alpha, Monoclonal Antibody (Cat# AAA438355)
Full Name
HIF1 alpha
Gene Names
HIF1A; HIF1; MOP1; PASD8; HIF-1A; bHLHe78; HIF-1alpha; HIF1-ALPHA
Reactivity
Human.
Applications
EIA, FC/FACS, IG
Pricing
$390/0.1 mg (With BSA & Azide at 0.2mg/mL) | $390/0.1 mg (Without BSA & Azide at 1mg/mL) | $215/0.02 mg (With BSA & Azide at 0.2mg/mL) | $1,710/5x0.1 mg (With BSA & Azide at 0.2mg/mL) | $1,710/5x0.1 mg (Without BSA & Azide at 1mg/mL)
SDS-Page
(SDS-PAGE Analysis Purified HIF1 alpha Mouse Monoclonal Antibody (ESEE122). Confirmation of Purity and Integrity of Antibody.)
HIF1 alpha (Hypoxia-Inducible Factor 1-alpha), Monoclonal Antibody (Cat# AAA4380979)
Full Name
HIF1 alpha (Hypoxia-Inducible Factor 1-alpha)
Gene Names
HIF1A; HIF1; MOP1; PASD8; HIF-1A; bHLHe78; HIF-1alpha; HIF1-ALPHA; HIF-1-alpha
Reactivity
Human, Cow, Dog, Mouse, Rat
Applications
EIA, FC/FACS, IF
Purity
Purified Ab with BSA and Azide at 200ug/ml OR Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
Pricing
$390/0.1 mg (With BSA & Azide at 0.2mg/mL) | $390/0.1 mg (Without BSA & Azide at 1mg/mL) | $215/0.02 mg (With BSA & Azide at 0.2mg/mL) | $1,710/5x0.1 mg (With BSA & Azide at 0.2mg/mL) | $1,710/5x0.1 mg (Without BSA & Azide at 1mg/mL)
Immunofluorescence
(Immunofluorescent staining using PI3 kinase p110 beta antibodyImmunofluorescence analysis of methanol-fixed HeLa, using PI3 kinase p110 beta antibody at 1:200 dilution.)
PI3, Polyclonal Antibody (Cat# AAA837209)
Full Name
PI3 kinase p110 beta antibody
Applications
IF, ICC, WB
Purity
PI3 kinase p110 beta antibody was purified by antigen-affinity chromatography
Pricing
$700/0.1 mL | $3,130/5x0.1 mL
Western Blot (WB)
(Western Blot Analysis of human spleen tissue lysate using HIF1 alpha Mouse Monoclonal Antibody (Ha111a).)
HIF1 alpha (Hypoxia-Inducible Factor 1-alpha), Monoclonal Antibody (Cat# AAA4381541)
Full Name
HIF1 alpha (Hypoxia-Inducible Factor 1-alpha)
Gene Names
HIF1A; HIF1; MOP1; PASD8; HIF-1A; bHLHe78; HIF-1alpha; HIF1-ALPHA; HIF-1-alpha
Reactivity
Human, Mouse, Chicken
Applications
EIA, IHC, WB
Purity
Purified Ab with BSA and Azide at 200ug/ml or Purified Ab with BSA and Azide at 200ug/ml or Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
Pricing
$390/0.1 mg (With BSA & Azide at 0.2mg/mL) | $390/0.1 mg (Without BSA & Azide at 1mg/mL) | $215/0.02 mg (With BSA & Azide at 0.2mg/mL) | $1,710/5x0.1 mg (With BSA & Azide at 0.2mg/mL) | $1,710/5x0.1 mg (Without BSA & Azide at 1mg/mL)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded human lung carcinoma tissue using PI3K P85 a/y/beta antibody (left) or the same antibody preincubated with with blocking peptide (right))
PI3K, Polyclonal Antibody (Cat# AAA835398)
Full Name
PI3K antibody
Applications
IHC
Purity
PI3K antibody was purified by immunoaffinity chromatography
Pricing
$375/0.05 mg | $1,675/5x0.05 mg
IC87114, PI3K Inhibitor, Biochemical (Cat# AAA6050756)
Full Name
IC87114, PI3K Inhibitor (2-[6-Amino-9H-purin-9-yl)methyl]-5-methyl-3-(2-methylphenyl)-4(3H)-quinazolinone)
Purity
Highly Purified
~95% (HPLC)
~95% (HPLC)
Pricing
$500/1 mg | $2,230/5x1 mg
Testing Data
()
Phosphoinositide 3 Kinase, p85 alpha, p110 delta, Active Protein (Cat# AAA636922)
Full Name
Phosphoinositide 3 Kinase, p85 alpha, p110 delta, Recombinant, Human (PI3K)
Gene Names
PIK3CD; PI3K; p110D; P110DELTA
Purity
Purified
~50% by SDS-PAGE
~50% by SDS-PAGE
Pricing
$740/0.02 mg | $3,320/5x0.02 mg
Western Blot (WB)
(Western blot analysis of extracts from C6 and RN33B cells using MBS610573.)
PI3 Kinase Class III, Polyclonal Antibody (Cat# AAA610573)
Full Name
PI3 Kinase Class III
Gene Names
LOC547983; PI3K; SPI3K-5
Reactivity
Human, Mouse, Rat
Applications
WB, IP
Purity
Purified peptide affinity chromatography.
Pricing
$610/0.1 mL | $2,730/5x0.1 mL
Testing Data
(Specific Activity: Lot-dependent. Sample Value: ~1200 pmol/min/ug.)
Phosphoinositide 3 Kinase, p120 gamma, full length, N-terminal His tag,, Active Protein (Cat# AAA635766)
Full Name
Phosphoinositide 3 Kinase, Recombinant, Human, p120 gamma, full length, N-terminal His tag, (PI3K)
Gene Names
SRC; ASV; SRC1; c-SRC; p60-Src
Reactivity
Human
Purity
80% by SDS-PAGE
Pricing
$740/0.02 mg | $3,320/5x0.02 mg
Structure
(Structure of T3631)
TGX-115, PI3K Inhibitor, Biochemical (Cat# AAA6118053)
Full Name
TGX-115, PI3K Inhibitor (8-(2-Methylphenoxy)-2-(4-morphonilyl)-4(1H)-quinolinone)
Purity
Highly Purified
~95% (HPLC)
~95% (HPLC)
Pricing
$465/1 mg | $2,090/5x1 mg
Testing Data
(specific activity)
Phosphoinositide 3 Kinase, p110 alpha, p85 alpha, Active Protein (Cat# AAA636424)
Full Name
Phosphoinositide 3 Kinase, Recombinant, Human, p110 alpha, p85 alpha (PI3K)
Gene Names
PIK3R1; p85; AGM7; GRB1; p85-ALPHA
Reactivity
Human
Purity
80% by SDS-PAGE
Pricing
$740/0.02 mg | $3,320/5x0.02 mg
Testing Data
()
PI 3-Kinase p110 beta/p85 alpha, Active Protein (Cat# AAA636545)
Full Name
PI 3-Kinase p110 beta/p85 alpha, Recombinant, Human
Gene Names
PIK3R1; p85; AGM7; GRB1; p85-ALPHA
Purity
Purified
0.7
0.7
Pricing
$740/0.02 mg | $3,320/5x0.02 mg
Testing Data
(PP242 is a novel potent and selective mTOR inhibitor with an IC50 of 8 nM. PP242 also shows residual (micromolar) activity against panel of tyrosine kinases. But PP242 was much less active against other PI3K family members with IC50 of 2, 2.2, 0.1, 1.3 and 0.41 uM for p110alpha, p110beta, p110delta, p110gamma and DNA-PK, respectively. PP242 inhibits other PI 3-Kinases only at much higher concentrations. PP242, but not rapamycin, causes death of mouse and human leukemia cells. In vivo, PP242 delays leukemia onset and augments the effects of the current front-line tyrosine kinase inhibitors more effectively than does rapamycin. PP242 was also more effective than rapamycin in achieving cytoreduction and apoptosis in multiple myeloma cells. In addition, PP242 was an effective agent against primary multiple myeloma cells in vitro and growth of 8226 cells in mice. Knockdown of the TORC2 complex protein, rictor, was deleterious to multiple myeloma cells further supporting TORC2 as the critical target for PP242. [1][2][3])
Structure
(Structure of G8989-10|2-(1H-indazol-4-yl)-6-((4-(methylsulfonyl)piperazin-1-yl)methyl)-4-morpholinothieno[3,2-d]pyrimidine; 4-[2-(1H-Indazol-4-yl)-6-[[4-(methylsulfonyl)piperazin-1-yl]methyl]thieno[3,2-d]pyrimidin-4-yl]morpholine; GDC 0941; GDC 941; GNE 0941; Pictilisib; Pictrelisib)
GDC-0941, PI3K Inhibitor, Biochemical (Cat# AAA6038245)
Full Name
GDC-0941, PI3K Inhibitor (2-(1H-Indazol-4-yl)-6-[[4-(methylsulfonyl)-1-piperazinyl]methyl]-4-(4-morpholinyl)-thieno[3,2- d]pyrimidine)
Purity
Highly Purified
~99% (HPLC)
~99% (HPLC)
Pricing
$270/25 mg | $385/50 mg | $605/100 mg | $2,720/5x100 mg
TGX-221, PI3K Inhibitor, Biochemical (Cat# AAA6041932)
Full Name
TGX-221, PI3K Inhibitor (+/-)-7-Methyl-2-(morpholin-4-yl)-9-(1-phenylaminoethyl)-pyrido[1,2-a]-pyrimidin-4-one)
Purity
Highly Purified
~98% (HPLC)
~98% (HPLC)
Pricing
$375/1 mg | $710/5 mg | $3,195/5x5 mg
PRMT1, Recombinant Protein (Cat# AAA5304496)
Full Name
PRMT1 protein
Gene Names
PRMT1; ANM1; HCP1; IR1B4; HRMT1L2
Purity
PRMT1 protein was purified using a a proprietary chromatographic technique.
Pricing
$295/0.01 mg | $1,310/5x0.01 mg
Western Blot (WB)
(Western blot analysis of PI3K p85 alpha/p55 gamma expression in HeLa (A); mouse brain (B); rat brain (C); rat muscle (D) whole cell lysates.)
PI3K p85 Alpha, Polyclonal Antibody (Cat# AAA5314829)
Full Name
PI3K p85 Alpha Antibody
Applications
WB, IHC, IF, ICC
Purity
Immunogen Affinity Chromatography
Pricing
$335/0.1 mL | $1,510/5x0.1 mL
Western Blot (WB)
(Western Blot analysis of extracts from 293 cells untreated or treated with sorbrtol using PI3K P85 (Phospho-Tyr467) antibody)
PI3K P85, Polyclonal Antibody (Cat# AAA5304956)
Full Name
Rabbit polyclonal PI3K P85 antibody
Gene Names
PIK3R2; p85; MPPH; P85B; MPPH1; p85-BETA
Applications
WB
Purity
Purified by immunoaffinity chromatography.
Pricing
$375/0.05 mg | $1,675/5x0.05 mg
PIK-inhibitors, Inhibitor (Cat# AAA578245)
Full Name
PIK-inhibitors (p110alpha-IN-1)
Purity
97.0%
Pricing
$195/1 mg | $230/2 mg | $270/5 mg | $365/10 mg | $555/25 mg | $680/50 mg | $2,795/5x50 mg
Western Blot (WB)
(Western blot analysis of PI3-kinase with lysate from Jurkat cells.)
PI3 kinase, Polyclonal Antibody (Cat# AAA5311564)
Full Name
PI3 kinase Antibody
Gene Names
PIK3C2G; PI3K-C2GAMMA; PI3K-C2-gamma
Applications
WB
Purity
Affinity Chromatography
Pricing
$460/0.1 mg | $2,070/5x0.1 mg
PI3K, Recombinant Protein (Cat# AAA5308872)
Full Name
Purified recombinant Human PI3K protein
Purity
Purified using a proprietary chromatographic technique.
Pricing
$565/0.005 mg | $2,365/5x0.005 mg
Chemical Structure
(Chemical structure of GDC 0941 (SIH-501), a pan-PI3K kinase inhibitor. CAS #: 957054-30-7. Molecular Formula: C23H27N7O3S2. Molecular Weight: 513.63 g/mol.)
GDC 0941, Small Molecule (Cat# AAA808200)
Full Name
GDC 0941
Purity
>=98%
Pricing
$240/5 mg | $490/25 mg | $1,975/5x25 mg | $850/5x5 mg
Western Blot (WB)
(Western blot analysis of PI3K p85 alpha expression in HeLa (A) whole cell lysates.)
PIK3R1, Polyclonal Antibody (Cat# AAA5316221)
Full Name
PIK3R1 Antibody
Gene Names
PIK3R1; p85; AGM7; GRB1; IMD36; p85-ALPHA
Applications
WB, IHC
Purity
Immunogen Affinity Chromatography
Pricing
$335/0.1 mL | $1,510/5x0.1 mL
Western Blot (WB)
(Western blot analysis of PI3K C2 gamma expression in CEM (A); HeLa (B); NIH3T3 (C); PC12 (D) whole cell lysates.)
PI3K C2 Gamma, Polyclonal Antibody (Cat# AAA5314827)
Full Name
PI3K C2 Gamma Antibody
Applications
WB
Purity
Immunogen Affinity Chromatography
Pricing
$335/0.1 mL | $1,510/5x0.1 mL
Immunohistochemistry (IHC)
(At 1/100 staining Human kidney cancer by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the primary antibody at 4 degree C overnight. An HRP conjugated anti-Rabbit antibody was used as the secondary antibody.)
Beclin 1, Polyclonal Antibody (Cat# AAA9612661)
Full Name
Phospho-Beclin 1 (Ser295) Antibody
Gene Names
BECN1; ATG6; VPS30; beclin1
Reactivity
Human, Mouse, Rat
Applications
IHC, IF, ICC, EIA
Purity
The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho-peptide and non-phospho-peptide affinity columns.
Pricing
$310/0.1 mL | $370/0.2 mL | $1,605/5x0.2 mL
Western Blot (WB)
(Western blot analysis of PI3K p85 beta expression in HepG2 (A); Raw264.7 (B); H9C2 (C) whole cell lysates.)
PI3K p85 beta, Polyclonal Antibody (Cat# AAA5314831)
Full Name
PI3K p85 beta Antibody
Applications
WB
Purity
Immunogen Affinity Chromatography
Pricing
$335/0.1 mL | $1,510/5x0.1 mL
Beclin 1, Polyclonal Antibody (Cat# AAA9613615)
Full Name
Beclin 1 Antibody
Gene Names
BECN1; ATG6; VPS30; beclin1
Reactivity
Human, Mouse, Rat
Applications
EIA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin
Pricing
$260/0.1 mL | $305/0.2 mL | $1,220/5x0.2 mL
Western Blot (WB)
(Western blot analysis of PI3K p85 beta expression in HepG2 (A); Raji (B) whole cell lysates.)
PI3K p85 beta, Polyclonal Antibody (Cat# AAA5314830)
Full Name
PI3K p85 beta Antibody
Applications
WB
Purity
Immunogen Affinity Chromatography
Pricing
$335/0.1 mL | $1,510/5x0.1 mL
Beclin 1, Polyclonal Antibody (Cat# AAA9613616)
Full Name
Beclin 1 Antibody
Gene Names
BECN1; ATG6; VPS30; beclin1
Reactivity
Human, Mouse, Rat
Applications
EIA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin
Pricing
$260/0.1 mL | $305/0.2 mL | $1,220/5x0.2 mL
Polyporenic acid C, Inhibitor (Cat# AAA5759903)
Full Name
Polyporenic acid C
Purity
98.00%
Pricing
$360/1 mg | $800/5 mg | $3,310/5x5 mg
Quiflapon sodium, Inhibitor (Cat# AAA5764354)
Full Name
Quiflapon sodium
Purity
98.00%
Pricing
$260/5 mg | $335/10 mg | $1,205/5x10 mg
PKC zeta, Polyclonal Antibody (Cat# AAA9630892)
Full Name
PKC zeta Antibody
Gene Names
PRKCZ; PKC2; PKC-ZETA
Reactivity
Human, Mouse, Rat
Applications
EIA, peptide
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Pricing
$260/0.1 mL | $305/0.2 mL | $1,220/5x0.2 mL
Structure
PIK-inhibitors, Inhibitor (Cat# AAA3607491)
Full Name
PIK-inhibitors
Purity
>98% (HPLC)
Pricing
$220/2 mg | $260/5 mg | $345/10 mg | $510/25 mg | $625/50 mg | $2,525/5x50 mg
Structure
VPS34 1 (Compound 19, PIK-III analogue), Inhibitor (Cat# AAA5758802)
Full Name
VPS34 inhibitor 1 (Compound 19, PIK-III analogue)
Purity
98.44%
Pricing
$260/2 mg | $345/5 mg | $810/25 mg | $345/1 mL (in DMSO) | $3,370/5x25 mg
Beclin 1, Polyclonal Antibody (Cat# AAA9612662)
Full Name
Phospho-Beclin 1 (Ser234) Antibody
Gene Names
BECN1; ATG6; VPS30; beclin1
Reactivity
Human, Mouse, Rat
Applications
EIA
Purity
The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho-peptide and non-phospho-peptide affinity columns.
Pricing
$310/0.1 mL | $370/0.2 mL | $1,605/5x0.2 mL
Testing Data
AS-605240, Inhibitor (Cat# AAA516404)
Full Name
AS-605240
Purity
>98% (TLC); NMR (conforms)
Pricing
$190/5 mg | $285/25 mg | $1,050/5x25 mg
