Uteroglobin Recombinant Protein | SCGB1A1 recombinant protein
Human Uteroglobin
Gene Names
SCGB1A1; UGB; UP1; CC10; CC16; CCSP; UP-1; CCPBP
Reactivity
Human
Purity
> 98% by SDS-PAGE & HPLC analyses
Synonyms
Uteroglobin; Human Uteroglobin; Urinary protein 1; CC10; Urine protein 1; Clara cell phospholipid-binding protein; CCPBP; SCGB1A1 recombinant protein
Host
E Coli
Reactivity
Human
Purity/Purification
> 98% by SDS-PAGE & HPLC analyses
Form/Format
Lyophilized from 1x PBS
Sequence
MEICPSFQRV IETLLMDTPS SYEAAMELFS PDQDMREAGA QLKKLV DTLP QKPRESIIKL MEKIAQSSLC N
Sequence Length
91
Reconstitution
Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/m. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer (e.g. PBS) containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.
Preparation and Storage
The lyophilized protein is stable at room temperature for 1 month and at 4°C for 6 months. Reconstituted working aliquots are stable for 1 week at 2°C to 8°C and for 3 months at -20°C to -80°C.
Related Product Information for SCGB1A1 recombinant protein
Uteroglobin, a member of the Secretoglobin superfamily, also known as Clara cell phospholipid-binding protein, is a multifunctional protein that can exert anti-inflammatory and anti-tumorigenic effects by binding small hydrophobic molecules such as phospholipids and prostaglandins. The small, non-glycosylated protein named for its high levels of expression in pre-implantation embryos, where it exhibits growth stimulatory effects, is produced and secreted by the non-ciliated, non-mucous Clara cells predominant in the epithelial surfaces of pulmonary airways, as well as other non-ciliated epithelia. Members of the Secretoglobin superfamily demonstrate a high level of structural conservation and are characterized as small, secretory homo- or heterodimers. In addition to sequestering pro-inflammatory mediators and carcinogens, Uteroglobin has been implicated in the inhibition of cell migration and invasion, platelet aggregation, and T cell differentiation. Recombinant Human Uteroglobin is an 8.0 kDa homodimeric protein consisting of 142 amino acid residues.
Product Categories/Family for SCGB1A1 recombinant protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
16.1 kDa (Dimer)
NCBI Official Full Name
uteroglobin
NCBI Official Synonym Full Names
secretoglobin, family 1A, member 1 (uteroglobin)
NCBI Official Symbol
SCGB1A1
NCBI Official Synonym Symbols
UGB; UP1; CC10; CC16; CCSP; UP-1; CCPBP
NCBI Protein Information
uteroglobin; blastokinin; urine protein 1; urinary protein 1; clara cells 10 kDa secretory protein; clara cell phospholipid-binding protein
UniProt Protein Name
Uteroglobin
Protein Family
UniProt Gene Name
SCGB1A1
UniProt Synonym Gene Names
CC10; CCSP; UGB; CCPBP; CC10; UP-1; UP1
UniProt Entry Name
UTER_HUMAN
NCBI Description
This gene encodes a member of the secretoglobin family of small secreted proteins. The encoded protein has been implicated in numerous functions including anti-inflammation, inhibition of phospholipase A2 and the sequestering of hydrophobic ligands. Defects in this gene are associated with a susceptibility to asthma. [provided by RefSeq, May 2010]
Uniprot Description
Function: Binds phosphatidylcholine, phosphatidylinositol, polychlorinated biphenyls (PCB) and weakly progesterone, potent inhibitor of phospholipase A2.
Subunit structure: Homodimer; antiparallel disulfide-linked.
Subcellular location: Secreted.
Tissue specificity: Clara cells (nonciliated cells of the surface epithelium of the pulmonary airways).
Sequence similarities: Belongs to the secretoglobin family.
Research Articles on SCGB1A1
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Product Notes
The SCGB1A1 scgb1a1 (Catalog #AAA691837) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The Human Uteroglobin reacts with Human and may cross-react with other species as described in the data sheet. The amino acid sequence is listed below: MEICPSFQRV IETLLMDTPS SYEAAMELFS PDQDMREAGA QLKKLV DTLP QKPRESIIKL MEKIAQSSLC N. It is sometimes possible for the material contained within the vial of "Uteroglobin, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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