Rat Cluster Of Differentiation 14 (CD14) ELISA Kit | CD14 elisa kit

Rat Cluster Of Differentiation 14 (CD14) ELISA Kit

Cat. Num. AAA453930

• Reactivity: Rat
• Synonyms: Cluster Of Differentiation 14 (CD14); Rat Cluster Of Differentiation 14 (CD14) ELISA Kit; Monocyte differentiation antigen CD14; Myeloid cell-specific leucine-rich glycoprotein; CD14 elisa kit

• Reactivity: Rat
• Sequence Length: 372

• Samples: Serum, plasma, tissue homogenates and other biological fluids.
• Assay Type: Sandwich
• Detection Range: 1.56-100ng/mL
• Sensitivity: 0.51ng/mL
• Intra Assay: CV<10%
• Inter Assay: CV<12%
• Preparation and Storage: For unopened kit, all reagents should be kept according to the labels on vials. The TMB Substrate, Wash Buffer, Stop Solution should be stored at 4 degree C. All others should be stored at -20 degree C.

Typical Testing Data/Standard Curve (for reference only)

NCBI and Uniprot Product Information

• NCBI GI #: 11120688
• NCBI GeneID: 60350
• NCBI Accession #: NP_068512.1
• NCBI GenBank Nucleotide #: NM_021744.1
• UniProt Accession #: Q63691; Q6GT04
• Molecular Weight: 40,054 Da
• NCBI Official Full Name: monocyte differentiation antigen CD14
• NCBI Official Synonym Full Names: CD14 molecule
• NCBI Official Symbol: Cd14
• NCBI Protein Information: monocyte differentiation antigen CD14
• UniProt Protein Name: Monocyte differentiation antigen CD14
• Protein Family: Monocyte differentiation antigen
• UniProt Gene Name: Cd14

NCBI Description

component of the lipopolysaccharide receptor complex; mediates LPS-induced neuroinflammation and inflammatory response [RGD, Feb 2006]

Uniprot Description

Coreceptor for bacterial lipopolysaccharide. In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the LY96/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Acts as a coreceptor for TLR2:TLR6 heterodimer in response to diacylated lipopeptides and for TLR2:TLR1 heterodimer in response to triacylated lipopeptides, these clusters trigger signaling from the cell surface and subsequently are targeted to the Golgi in a lipid-raft dependent pathway. Binds electronegative LDL (LDL-) and mediates the cytokine release induced by LDL- ().