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Peroxiredoxin 6 (PRDX6) Recombinant Protein | PRDX6 recombinant protein
Recombinant Peroxiredoxin 6 (PRDX6)
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NCBI and Uniprot Product Information
Accurate Molecular Weight: 30kDa
NCBI Description
This gene encodes a member of the peroxiredoxin family of peroxidases. The encoded protein is a bifunctional enzyme that has glutathione peroxidase and phospholipase activities. This protein is an antioxidant that reduces peroxidized membrane phospholipids and plays an important role in phospholipid homeostasis based on its ability to generate lysophospholipid substrate for the remodeling pathway of phospholipid synthesis. Mice lacking this gene are sensitive to oxidant stress, have altered lung phospholipid metabolism and susceptible to skin tumorigenesis. Alternate splicing of this gene results in multiple transcript variants. A pseudogene of this gene is found on chromosome 4. [provided by RefSeq, Dec 2014]
Uniprot Description
PRDX6: Involved in redox regulation of the cell. Can reduce H(2)O(2) and short chain organic, fatty acid, and phospholipid hydroperoxides. May play a role in the regulation of phospholipid turnover as well as in protection against oxidative injury. Belongs to the AhpC/TSA family. Rehydrin subfamily.
Protein type: Amino Acid Metabolism - phenylalanine; EC 1.11.1.15; EC 1.11.1.9; Energy Metabolism - methane; Oxidoreductase; Phospholipase
Chromosomal Location of Human Ortholog: 1 H2.1|1 69.75 cM
Cellular Component: cytoplasm; cytosol; extracellular exosome; extracellular space; lysosome; membrane; mitochondrion; nucleus; perinuclear region of cytoplasm
Molecular Function: antioxidant activity; cadherin binding; calcium-independent phospholipase A2 activity; catalytic activity; glutathione peroxidase activity; hydrolase activity; oxidoreductase activity; peroxidase activity; peroxiredoxin activity; phospholipase A2 activity; protein binding; protein homodimerization activity; ubiquitin protein ligase binding
Biological Process: bleb formation; cell redox homeostasis; cellular oxidant detoxification; glycerophospholipid catabolic process; hydrogen peroxide catabolic process; lipid catabolic process; lipid metabolic process; metabolic process; positive regulation of mRNA splicing, via spliceosome; response to oxidative stress; response to reactive oxygen species
Research Articles on PRDX6
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Product Notes
The PRDX6 prdx6 (Catalog #AAA2097674) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The Recombinant Peroxiredoxin 6 (PRDX6) reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's Peroxiredoxin 6 (PRDX6) can be used in a range of immunoassay formats including, but not limited to, Positive Control, Immunogen, SDS-PAGE, Western Blot (WB). Researchers should empirically determine the suitability of the PRDX6 prdx6 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Peroxiredoxin 6 (PRDX6), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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