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SDS-PAGE (3ug by SDS-PAGE under reducing condition and visualized fby coomassie blue stain.)

Peroxiredoxin 6 Active Protein | PRDX6 active protein

Peroxiredoxin 6, 1-224aa, Human, His tag, E Coli (Bioactivity Validated)

Gene Names
PRDX6; PRX; p29; AOP2; 1-Cys; NSGPx; aiPLA2; HEL-S-128m
Applications
SDS-Page
Purity
> 95% by SDS-PAGE
Synonyms
Peroxiredoxin 6; 1-224aa; Human; His tag; E Coli (Bioactivity Validated); 1-Cys; aiPLA2; AOP2; NSGPx; p29; PRX; Peroxiredoxin6; PRDX6; PRDX 6; PRDX-6; AA690119; Prdx6 rs3; 1 Cys; 1 Cys peroxiredoxin; 1 Cys PRX; 1 cysPrx; 24 kDa protein; 9430088D19Rik; Acidic calcium independent phospholipase A2; Antioxidant protein 2; Aop2 rs3; Brp 12; mKIAA0106; Ciliary body glutathione peroxidase; CP 3; EC 1.11.1.15; EC 1.11.1.7; EC 3.1.1; GPx; KIAA0106; Liver 2D page spot 40; Ltw4; Lvtw 4; MGC46173; Non selenium glutathione peroxidase; ORF06; OTTHuMP00000032693; PHGPx; Phospholipase A2 lysosomal; PLA2; Prdx5; Red blood cells page spot 12; Thiol specific antioxidant protein; ; PRDX6 active protein
Ordering
For Research Use Only!
Host
E Coli
Purity/Purification
> 95% by SDS-PAGE
Form/Format
Liquid. In 20mM Tris-HCl Buffer (pH 8.0) containing 20% glycerol
Concentration
1 mg/ml (determined by Bradford assay) (varies by lot)
Applicable Applications for PRDX6 active protein
Enzyme Activity, SDS-PAGE
Domain
1-224aa
Tag Information
His-tag
Preparation and Storage
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

SDS-PAGE

(3ug by SDS-PAGE under reducing condition and visualized fby coomassie blue stain.)

SDS-PAGE (3ug by SDS-PAGE under reducing condition and visualized fby coomassie blue stain.)
Related Product Information for PRDX6 active protein
Specific activity is >2,000 pmol/min/ug. Enzymatic activity is defined as the amount of hydroperoxide that 1ug of enzyme can reduce at 25C for 1minute.
Product Categories/Family for PRDX6 active protein
References
Davison EJ., et al. (2009). Proteomics. 9 (18):4284-97.; Wu J., et al. (2009). Chem Res Toxicol. 22 (4):668-75.;

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
27.1 kDa (244aa), confirmed by MALDI-TOF.
NCBI Official Full Name
peroxiredoxin-6
NCBI Official Synonym Full Names
peroxiredoxin 6
NCBI Official Symbol
PRDX6
NCBI Official Synonym Symbols
PRX; p29; AOP2; 1-Cys; NSGPx; aiPLA2; HEL-S-128m
NCBI Protein Information
peroxiredoxin-6
UniProt Protein Name
Peroxiredoxin-6
Protein Family
UniProt Gene Name
PRDX6
UniProt Synonym Gene Names
AOP2; KIAA0106; aiPLA2; NSGPx

NCBI Description

The protein encoded by this gene is a member of the thiol-specific antioxidant protein family. This protein is a bifunctional enzyme with two distinct active sites. It is involved in redox regulation of the cell; it can reduce H(2)O(2) and short chain organic, fatty acid, and phospholipid hydroperoxides. It may play a role in the regulation of phospholipid turnover as well as in protection against oxidative injury. [provided by RefSeq, Jul 2008]

Uniprot Description

Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Can reduce H2O2 and short chain organic, fatty acid, and phospholipid hydroperoxides. Also has phospholipase activity, and can therefore either reduce the oxidized sn-2 fatty acyl grup of phospholipids (peroxidase activity) or hydrolyze the sn-2 ester bond of phospholipids (phospholipase activity). These activities are dependent on binding to phospholipids at acidic pH and to oxidized phospholipds at cytosolic pH. Plays a role in cell protection against oxidative stress by detoxifying peroxides and in phospholipid homeostasis.

Research Articles on PRDX6

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Product Notes

The PRDX6 prdx6 (Catalog #AAA203357) is an Active Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The tag for this protein is His-tag. AAA Biotech's Peroxiredoxin 6 can be used in a range of immunoassay formats including, but not limited to, Enzyme Activity, SDS-PAGE. Researchers should empirically determine the suitability of the PRDX6 prdx6 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Peroxiredoxin 6, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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