Immunohistochemistry (IHC)
(Human Breast (formalin-fixed, paraffin-embedded) stained with ZMYM2 antibody at 10ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody alkaline phosphatase-streptavidin and chromogen.)
Rabbit anti-Human ZMYM2 Polyclonal Antibody | anti-ZMYM2 antibody
ZMYM2 (Zinc Finger MYM-type Protein 2, Zinc Finger Protein 198, Fused In Myeloproliferative Disorders Protein, Rearranged In Atypical Myeloproliferative Disorder Protein, FIM, RAMP, ZNF198)
Purified by immunoaffinity chromatography.
Purified by immunoaffinity chromatography.
Dilution: Western Blot: 0.1-1ug/ml
Immunohistochemistry (Formalin fixed paraffin embedded): 10ug/ml
Immunohistochemistry (IHC)
(Human Breast (formalin-fixed, paraffin-embedded) stained with ZMYM2 antibody at 10ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody alkaline phosphatase-streptavidin and chromogen.)
Immunohistochemistry (IHC)
(Human Breast (formalin-fixed, paraffin-embedded) stained with ZMYM2 antibody at 10ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody alkaline phosphatase-streptavidin and chromogen.)
Western Blot (WB)
(Western blot analysis of Zinc finger protein 198 in mouse skeletal muscle lysate in the 1) absence and 2) presence of immunizing peptide using antibody at 0.1ug/ml.)
Western Blot (WB)
(Western blot analysis of Zinc finger protein 198 in mouse skeletal muscle lysate in the 1) absence and 2) presence of immunizing peptide using antibody at 0.1ug/ml.)
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is a zinc finger protein that may act as a transcription factor. The encoded protein may be part of a BHC histone deacetylase complex. Translocation of this gene with the fibroblast growth factor receptor-1 gene (FGFR1) results in a fusion gene, which may be a cause of stem cell leukemia lymphoma syndrome (SCLL). Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2010]
Uniprot Description
ZNF198: a probable transcriptional regulator of the krueppel C2H2-type zinc-finger protein family. The translocation between FGFR and ZNF198 (8;13)(p11;q12) is oncogenic, causing stem cell leukemia lymphoma syndrome (SCLL), a myeloproliferative disorder (MPD) that evolves to acute myeloid leukemia and/or lymphoma. The transforming activity of ZNF198-FGFR1 requires the proline-rich domains, but not the ZNF domains, of ZNF198.
Protein type: Transcription factor
Chromosomal Location of Human Ortholog: 13q11-q12
Cellular Component: PML body; cytosol
Molecular Function: zinc ion binding; ubiquitin conjugating enzyme binding
Biological Process: regulation of transcription, DNA-dependent; transcription, DNA-dependent
Research Articles on ZMYM2
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Product Notes
The ZMYM2 zmym2 (Catalog #AAA645478) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ZMYM2 (Zinc Finger MYM-type Protein 2, Zinc Finger Protein 198, Fused In Myeloproliferative Disorders Protein, Rearranged In Atypical Myeloproliferative Disorder Protein, FIM, RAMP, ZNF198) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's ZMYM2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). Suitable for use in Western Blot and Immunohistochemistry. Dilution: Western Blot: 0.1-1ug/ml Immunohistochemistry (Formalin fixed paraffin embedded): 10ug/ml. Researchers should empirically determine the suitability of the ZMYM2 zmym2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ZMYM2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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