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Testing Data (Image: Striatin Antibody immunofluorescent staining of NIH3T3 cells.)

Striatin Antibody | anti-STRN antibody

Striatin, Antiserum, Rabbit

Gene Names
STRN; SG2NA; PPP2R6A
Reactivity
Human, Mouse, Rat
Applications
Immunofluorescence, Western Blot, Immunoprecipitation
Synonyms
Striatin; Antiserum; Rabbit; anti-STRN antibody
Ordering
For Research Use Only!
Reactivity
Human, Mouse, Rat
Form/Format
Whole serum - Liquid
Sequence Length
780
Applicable Applications for anti-STRN antibody
Immunofluorescence (IF), Western Blot (WB), Immunoprecipitation (IP)
Type Info
Rabbit IgG
Immunogen
Synthetic peptide made to an internal portion of the human protein (within residues 350-400). [Swiss-Prot# O43815].

Testing Data

(Image: Striatin Antibody immunofluorescent staining of NIH3T3 cells.)

Testing Data (Image: Striatin Antibody immunofluorescent staining of NIH3T3 cells.)

Testing Data

(Image: Immunoblot of PP2A immunoprecipitate with Striatin)

Testing Data (Image: Immunoblot of PP2A immunoprecipitate with Striatin)
Related Product Information for anti-STRN antibody
Striatin, an intraneuronal, calmodulin-binding protein addressed to dendrites and spines, is expressed in the motor system, particularly the striatum and motoneurons. Striatin contains a high number of domains mediating protein-protein interactions, suggesting a role within a dendritic Ca2+-signaling pathway.

It also binds Protein phosphatase 2A (PP2A) A and C subunits. It is a member of a family of proteins that also includes SG2NA and Zinedin.
Product Categories/Family for anti-STRN antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
80,761 Da
NCBI Official Full Name
striatin
NCBI Official Synonym Full Names
striatin
NCBI Official Symbol
STRN
NCBI Official Synonym Symbols
SG2NA; PPP2R6A
NCBI Protein Information
striatin
UniProt Protein Name
Striatin
Protein Family
UniProt Gene Name
STRN
UniProt Entry Name
STRN_HUMAN

Uniprot Description

STRN: Calmodulin-binding protein which may function as scaffolding or signaling protein and may play a role in dendritic Ca(2+) signaling. Belongs to the WD repeat striatin family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Cell development/differentiation; Protein phosphatase, regulatory subunit; Adaptor/scaffold

Chromosomal Location of Human Ortholog: 2p22.2

Cellular Component: postsynaptic membrane; protein phosphatase type 2A complex; tight junction; membrane; cell soma; postsynaptic density; cytoplasm; dendritic spine

Molecular Function: calmodulin binding; protein binding; protein phosphatase 2A binding; protein complex binding; estrogen receptor binding

Biological Process: negative regulation of cell proliferation; Wnt receptor signaling pathway; dendrite development; locomotory behavior

Research Articles on STRN

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Product Notes

The STRN strn (Catalog #AAA555119) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The Striatin, Antiserum, Rabbit reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Striatin can be used in a range of immunoassay formats including, but not limited to, Immunofluorescence (IF), Western Blot (WB), Immunoprecipitation (IP). Researchers should empirically determine the suitability of the STRN strn for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Striatin, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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