Western Blot (WB)
(Mouse Wee2 Antibody (Center) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the Wee2 antibody detected the Wee2 protein (arrow).)
Rabbit anti-Human, mouse Wee2 Polyclonal Antibody | anti-Wee2 antibody
Mouse Wee2 Antibody (Center)
Western Blot (WB)
(Mouse Wee2 Antibody (Center) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the Wee2 antibody detected the Wee2 protein (arrow).)
Western Blot (WB)
(Mouse Wee2 Antibody (Center) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the Wee2 antibody detected the Wee2 protein (arrow).)
Immunohistochemistry (IHC)
(Mouse Wee2 Antibody (Center) (MBS9207770)immunohistochemistry analysis in formalin fixed and paraffin embedded mouse ovarian tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of Mouse Wee2 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)
Immunohistochemistry (IHC)
(Mouse Wee2 Antibody (Center) (MBS9207770)immunohistochemistry analysis in formalin fixed and paraffin embedded mouse ovarian tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of Mouse Wee2 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)
Joshi, S., et al. BMC Dev. Biol. 7, 67 (2007) :
Han, S.J., et al. Curr. Biol. 15(18):1670-1676(2005)
Nakanishi, M., et al. Genes Cells 5(10):839-847(2000)
NCBI and Uniprot Product Information
Uniprot Description
WEE1B: a protein kinase of the WEE family expressed only in oocytes. Downregulation by RNAi causes a leaky meiotic arrest. The inhibitory effects of the kinase are enhanced when Ser15 is phosphorylated. Appears to be a key MPF inhibitory kinase in mouse oocytes and is required for maintaining meiotic arrest.
Protein type: Protein kinase, Other; Protein kinase, Ser/Thr (non-receptor); EC 2.7.10.2; Kinase, protein; Other group; WEE family; WEE1 subfamily
Cellular Component: nucleoplasm; cytoplasm; nucleus
Molecular Function: transferase activity; protein-tyrosine kinase activity; metal ion binding; transferase activity, transferring phosphorus-containing groups; non-membrane spanning protein tyrosine kinase activity; magnesium ion binding; nucleotide binding; kinase activity; ATP binding; protein kinase activity
Biological Process: mitosis; peptidyl-tyrosine phosphorylation; meiotic cell cycle; female pronucleus formation; negative regulation of cyclin-dependent protein kinase activity; female meiosis; protein amino acid phosphorylation; phosphorylation
Research Articles on Wee2
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Product Notes
The Wee2 wee2 (Catalog #AAA9207770) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 364-393. The Mouse Wee2 Antibody (Center) reacts with Human, mouse and may cross-react with other species as described in the data sheet. AAA Biotech's Wee2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC). WB~~1:1000. Researchers should empirically determine the suitability of the Wee2 wee2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Wee2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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