Immunohistochemistry (IHC)
(The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using WEE2 Antibody at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: x200))
Rabbit anti-Human WEE2 Polyclonal Antibody | anti-WEE2 antibody
WEE2 Antibody
Gene Names
WEE2; WEE1B
Reactivity
Human
Applications
Immunohistochemistry
Purity
Antigen affinity purification
Synonyms
WEE2; Polyclonal Antibody; WEE2 Antibody; WEE1B; anti-WEE2 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Specificity
The antibody detects endogenous levels of total WEE2 protein.
Purity/Purification
Antigen affinity purification
Form/Format
Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
Concentration
1mg/ml (varies by lot)
Sequence Length
567
Applicable Applications for anti-WEE2 antibody
Immunohistochemistry (IHC)
Application Notes
Immunohistochemistry: 1: 20-100
Immunogen
Synthetic peptide of human WEE2
Immunogen Type
Peptide
Preparation and Storage
Store at -20 degree C
Immunohistochemistry (IHC)
(The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using WEE2 Antibody at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: x200))
Immunohistochemistry (IHC)
(The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using WEE2 Antibody at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: x200))
Immunohistochemistry (IHC)
(The image on the left is immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using WEE2 Antibody at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: x200))
Immunohistochemistry (IHC)
(The image on the left is immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using WEE2 Antibody at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: x200))
Related Product Information for anti-WEE2 antibody
Wee 2 (Wee1-like protein kinase 2), also known as WEE1B, is a 567 amino acid nuclear protein belonging to the protein kinase superfamily. Expressed in testis, Wee 2 phosphorylates and inhibits Cdc2 and may act as a negative regulator of entry into the G2 to M transition of mitosis. The gene encoding Wee 2 is located on human chromosome 7, which houses over 1,000 genes and comprises nearly 5% of the human genome. Defects in some of the genes localized to chromosome 7 have been linked to Osteogenesis imperfecta, Williams-Beuren syndrome, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome.
Product Categories/Family for anti-WEE2 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
62,925 Da
NCBI Official Full Name
wee1-like protein kinase 2
NCBI Official Synonym Full Names
WEE1 homolog 2
NCBI Official Symbol
WEE2
NCBI Official Synonym Symbols
WEE1B
NCBI Protein Information
wee1-like protein kinase 2
UniProt Protein Name
Wee1-like protein kinase 2
Protein Family
UniProt Gene Name
WEE2
UniProt Synonym Gene Names
WEE1B
UniProt Entry Name
WEE2_HUMAN
Uniprot Description
WEE1B: a protein kinase of the WEE family expressed only in oocytes. Downregulation by RNAi causes a leaky meiotic arrest. The inhibitory effects of the kinase are enhanced when Ser15 is phosphorylated. Appears to be a key MPF inhibitory kinase in mouse oocytes and is required for maintaining meiotic arrest.
Protein type: EC 2.7.10.2; Kinase, protein; Other group; Protein kinase, Other; Protein kinase, Ser/Thr (non-receptor); WEE family; WEE1 subfamily
Chromosomal Location of Human Ortholog: 7q32
Cellular Component: cytoplasm; nucleoplasm
Biological Process: female meiosis; female pronucleus formation
Similar Products
Product Notes
The WEE2 wee2 (Catalog #AAA9417397) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The WEE2 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's WEE2 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC). Immunohistochemistry: 1: 20-100. Researchers should empirically determine the suitability of the WEE2 wee2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "WEE2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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