Rabbit vacuolar protein sorting 33 homolog A Polyclonal Antibody | anti-VPS33A antibody

Rabbit anti-human vacuolar protein sorting 33 homolog A (S. cerevisiae) polyclonal Antibody

Cat. Num. AAA710561

• Reactivity: Human, Mouse, Rat
• Applications: ELISA, Western Blot
• Purity: Antigen Affinity Purified
• Synonyms: vacuolar protein sorting 33 homolog A; Polyclonal Antibody; Rabbit anti-human vacuolar protein sorting 33 homolog A (S. cerevisiae) polyclonal Antibody; vacuolar protein sorting 33 homolog A (S. cerevisiae); VPS33A; FLJ22395; FLJ23187; anti-VPS33A antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Antigen Affinity Purified
• Sequence Length: 596

• Applicable Applications for anti-VPS33A antibody: ELISA (EIA), Western Blot (WB)
• Immunogen: Human VPS33A
• Storage Buffer: PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.

NCBI and Uniprot Product Information

• NCBI GI #: 16741627
• NCBI GeneID: 65082
• Molecular Weight: 67,611 Da
• NCBI Official Full Name: Vacuolar protein sorting 33 homolog A (S. cerevisiae)
• NCBI Official Synonym Full Names: vacuolar protein sorting 33 homolog A (S. cerevisiae)
• NCBI Official Symbol: VPS33A
• NCBI Protein Information: vacuolar protein sorting-associated protein 33A; hVPS33A; vacuolar protein sorting 33A
• UniProt Protein Name: Vacuolar protein sorting-associated protein 33A
• Protein Family: Vacuolar protein sorting-associated protein
• UniProt Gene Name: VPS33A
• UniProt Synonym Gene Names: hVPS33A
• UniProt Entry Name: VP33A_HUMAN

NCBI Description

Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene is a member of the Sec-1 domain family, and it encodes a protein similar to the yeast class C Vps33 protein. The mammalian class C VPS proteins are predominantly associated with late endosomes/lysosomes, and like their yeast counterparts, may mediate vesicle trafficking steps in the endosome/lysosome pathway. [provided by RefSeq, Jul 2008]

Uniprot Description

VPS33A: May play a role in vesicle-mediated protein trafficking to lysosomal compartments and in membrane docking/fusion reactions of late endosomes/lysosomes. Belongs to the STXBP/unc-18/SEC1 family.

Chromosomal Location of Human Ortholog: 12q24.31

Cellular Component: lysosomal membrane; late endosome membrane; perinuclear region of cytoplasm; early endosome; late endosome

Molecular Function: protein binding

Biological Process: vesicle-mediated transport; protein transport; lysosome localization; melanosome localization; regulation of pigmentation during development; platelet formation; vesicle docking during exocytosis