Rabbit anti-Human, Mouse USP45 Polyclonal Antibody | anti-USP45 antibody

USP45, ID (USP45, Ubiquitin carboxyl-terminal hydrolase 45, Deubiquitinating enzyme 45, Ubiquitin thioesterase 45, Ubiquitin-specific-processing protease 45)

Cat. Num. AAA646791

• Reactivity: Human, Mouse
• Applications: ELISA, Western Blot, Immunohistochemistry
• Purity: Affinity Purified; Purified by Protein A affinity chromatography.
• Synonyms: USP45; Polyclonal Antibody; ID (USP45; Ubiquitin carboxyl-terminal hydrolase 45; Deubiquitinating enzyme 45; Ubiquitin thioesterase 45; Ubiquitin-specific-processing protease 45); Anti -USP45; anti-USP45 antibody

• Host: Rabbit
• Reactivity: Human, Mouse
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Human, mouse
• Purity/Purification: Affinity Purified; Purified by Protein A affinity chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

• Applicable Applications for anti-USP45 antibody: ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)
• Application Notes: Suitable for use in Western Blot, Immunohistochemistry, ELISA; Dilution: ELISA: 1:1,000; Western Blot: 1:100-500; Immunohistochemistry: 1:10-50
• Immunogen: USP45 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 308-338 amino acids from the Central region of human USP45.
• Preparation and Storage: May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(USP45 Antibody (Center) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the USP45 antibody detected the USP45 protein (arrow).)

Western Blot (WB)

(USP45 Antibody (Center) western blot analysis in mouse cerebellum tissue lysates (35ug/lane).This demonstrates the USP45 antibody detected the USP45 protein (arrow).)

Immunohistochemistry (IHC)

(USP45 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of USP45 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)

Related Product Information for anti-USP45 antibody

The function of this protein remains unknown.

Product Categories/Family for anti-USP45 antibody

Antibodies; Abs to Ubiquitin

NCBI and Uniprot Product Information

• NCBI GI #: 13543681
• NCBI GeneID: 85015
• UniProt Accession #: Q70EL2; Q5T062; Q86T44; Q86TC0; Q9BRU1; B2RXG0
• Molecular Weight: 91,733 Da
• NCBI Official Full Name: USP45 protein
• NCBI Official Synonym Full Names: ubiquitin specific peptidase 45
• NCBI Official Symbol: USP45
• NCBI Protein Information: ubiquitin carboxyl-terminal hydrolase 45; ubiquitin thioesterase 45; deubiquitinating enzyme 45; ubiquitin thiolesterase 45; ubiquitin specific protease 45; ubiquitin-specific-processing protease 45
• UniProt Protein Name: Ubiquitin carboxyl-terminal hydrolase 45
• Protein Family: Ubiquitin carboxyl-terminal hydrolase
• UniProt Gene Name: USP45
• UniProt Entry Name: UBP45_HUMAN

Uniprot Description

Catalytic activity: Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal). Ref.1

Tissue specificity: Broadly expressed, with highest levels in ovary, skeletal muscle and spleen. Ref.1

Sequence similarities: Belongs to the peptidase C19 family.Contains 1 UBP-type zinc finger.

Sequence caution: The sequence CAI17192.1 differs from that shown. Reason: Erroneous gene model prediction. The sequence CAI19761.1 differs from that shown. Reason: Erroneous gene model prediction.