GDI1 Antibody | anti-GDI1 antibody

GDI1 Antibody

Cat. Num. AAA8516786

• Gene Names: GDI1; 1A; GDIL; MRX41; MRX48; OPHN2; XAP-4; RABGD1A; RABGDIA
• Reactivity: Human, Mouse, Rat
• Applications: Western Blot, Immunohistochemistry
• Purity: Immunogen affinity purified
• Synonyms: GDI1; GDI1 Antibody; 1A; GDIL; MRX41; MRX48; OPHN2; XAP-4; RABGD1A; RABGDIA;; anti-GDI1 antibody

• Reactivity: Human, Mouse, Rat
• Specificity: GDI1 Antibody detects endogenous levels of total GDI1
• Purity/Purification: Immunogen affinity purified
• Form/Format: In phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Sequence Length: 447

• Applicable Applications for anti-GDI1 antibody: Western Blot (WB), Immunohistochemistry (IHC)
• Application Notes: WB: 1:500-1:2000; IHC: 1:50-1:200
• Immunogen: Recombinant protein of human GDI1
• Preparation and Storage: Store at-20 degree C for 1 year

Western Blot (WB)

(Western blot analysis of extracts of HeLaand H3 protein, using H3K14me2 antibody.)

Related Product Information for anti-GDI1 antibody

GDP dissociation inhibitors are proteins that regulate the GDP-GTP exchange reaction of members of the rab family, small GTP-binding proteins of the ras superfamily, that are involved in vesicular trafficking of molecules between cellular organelles. GDIs slow the rate of dissociation of GDP from rab proteins and release GDP from membrane-bound rabs. GDI1 is expressed primarily in neural and sensory tissues. Mutations in GDI1 have been linked to X-linked nonspecific mental retardation.

NCBI and Uniprot Product Information

• NCBI GI #: 4503971
• NCBI GeneID: 2664
• NCBI Accession #: NP_001484.1
• NCBI GenBank Nucleotide #: NM_001493.2
• UniProt Accession #: P31150; P50394; Q6FG50; Q7Z2G6; Q7Z2G9; Q7Z2H5; Q7Z2I6
• Molecular Weight: 55kDa
• NCBI Official Full Name: rab GDP dissociation inhibitor alpha
• NCBI Official Synonym Full Names: GDP dissociation inhibitor 1
• NCBI Official Symbol: GDI1
• NCBI Official Synonym Symbols: 1A; GDIL; MRX41; MRX48; OPHN2; XAP-4; RABGD1A; RABGDIA
• NCBI Protein Information: rab GDP dissociation inhibitor alpha
• UniProt Protein Name: Rab GDP dissociation inhibitor alpha
• Protein Family: Guanosine nucleotide diphosphate dissociation inhibitor
• UniProt Gene Name: GDI1
• UniProt Synonym Gene Names: GDIL; OPHN2; RABGDIA; XAP4; Rab GDI alpha; GDI-1

NCBI Description

GDP dissociation inhibitors are proteins that regulate the GDP-GTP exchange reaction of members of the rab family, small GTP-binding proteins of the ras superfamily, that are involved in vesicular trafficking of molecules between cellular organelles. GDIs slow the rate of dissociation of GDP from rab proteins and release GDP from membrane-bound rabs. GDI1 is expressed primarily in neural and sensory tissues. Mutations in GDI1 have been linked to X-linked nonspecific cognitive disability. [provided by RefSeq, Jul 2008]

Uniprot Description

Regulates the GDP/GTP exchange reaction of most Rab proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them. Promotes the dissociation of GDP-bound Rab proteins from the membrane and inhibits their activation. Promotes the dissociation of RAB1A, RAB3A, RAB5A and RAB10 from membranes.