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Western Blot (WB) (Western Blot analysis of TWEAKR on different lysates using anti-TWEAKR antibody at 1/1,000 dilution. Positive control: Lane 1: NIH/3T3 Lane 2: C2C12)

Rabbit TWEAKR Polyclonal Antibody | anti-TWEAKR antibody

TWEAKR Polyclonal Antibody

Gene Names
Tnfrsf12a; Fn14
Reactivity
Human, Mouse, Rat
Applications
Western Blot, Immunohistochemistry, Immunoprecipitation
Purity
ProA affinity purified
Synonyms
TWEAKR; Polyclonal Antibody; TWEAKR Polyclonal Antibody; FGF-inducible 14; TweakR; TNFRSF12A; CD 266; CD266; CD266 antigen; FGF inducible 14; Fibroblast growth factor inducible immediate early response protein 14; Fibroblast growth factor-inducible immediate-early response protein 14; FN 14; FN14; TNFRSF 12A; TNR12; Tumor necrosis factor receptor superfamily member 12A; TWEAK R; Tweak receptor; Tweak-receptor; anti-TWEAKR antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
TWEAKR polyclonal antibody detects endogenous levels of TWEAKR protein.
Purity/Purification
ProA affinity purified
Form/Format
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Applicable Applications for anti-TWEAKR antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)
Application Notes
WB: 1:500-1:1,000
IHC: 1:50-1:200
Immunogen
recombinant protein
Preparation and Storage
Store at 4 degree C after thawing.
Aliquot store at -20 degree C or -80 degree C.
Avoid repeated freeze/thaw cycles.

Western Blot (WB)

(Western Blot analysis of TWEAKR on different lysates using anti-TWEAKR antibody at 1/1,000 dilution. Positive control: Lane 1: NIH/3T3 Lane 2: C2C12)

Western Blot (WB) (Western Blot analysis of TWEAKR on different lysates using anti-TWEAKR antibody at 1/1,000 dilution. Positive control: Lane 1: NIH/3T3 Lane 2: C2C12)

Immunohistochemistry (IHC)

(Immunohistochemical analysis of paraffin-embedded mouse uterus tissue using anti-TWEAKR antibody. Counter stained with hematoxylin.)

Immunohistochemistry (IHC) (Immunohistochemical analysis of paraffin-embedded mouse uterus tissue using anti-TWEAKR antibody. Counter stained with hematoxylin.)
Related Product Information for anti-TWEAKR antibody
Fn14, the TWEAK receptor, is a recently identified member of the TNF receptor superfamily and is expressed on smooth muscle cells and endothelial cells. It is a weak inducer of apoptosis and promotes angiogenesis. Fn14 is a type 1 membrane protein. It associates with TRAF1 and TRAF2, and may modulate cellular adhesion to matrix proteins. Fn14 is highly expressed in heart, placenta and kidney, and moderately expressed in lung, skeletal muscle and pancreas. It is the smallest member of the TNF receptor (TNFR) superfamily described to date, and signals via recruitment of several different TNFR-associated factors.

NCBI and Uniprot Product Information

NCBI GeneID
UniProt Accession #
Molecular Weight
14kDa
NCBI Official Synonym Full Names
TNF receptor superfamily member 12A
NCBI Official Symbol
Tnfrsf12a
NCBI Official Synonym Symbols
Fn14
NCBI Protein Information
tumor necrosis factor receptor superfamily member 12A

NCBI Description

human homolog is a receptor that binds TWEAK, a member of the TNF family, and is involved in cell proliferation, adhesion and angiogenesis [RGD, Feb 2006]

Research Articles on TWEAKR

Similar Products

Product Notes

The TWEAKR (Catalog #AAA3013619) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TWEAKR Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's TWEAKR can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP). WB: 1:500-1:1,000 IHC: 1:50-1:200. Researchers should empirically determine the suitability of the TWEAKR for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TWEAKR, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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