Immunohistochemistry (IHC)
(Immunochemical staining of human Trim69 in human testis with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections.)
Rabbit anti-Human Trim69 Polyclonal Antibody | anti-Trim69 antibody
Anti-Trim69 Antibody, Rabbit Polyclonal
Reactivity
Human
Applications
Immunohistochemistry
Purity
Protein A & Antigen Affinity
Synonyms
Trim69; Polyclonal Antibody; Anti-Trim69 Antibody; Rabbit Polyclonal; Trim69 Antibody; Rabbit PAb; Antigen Affinity Purified; Anti-hCG_39321 Antibody; Anti-HSD34 Antibody; Anti-RNF36 Antibody; Anti-Trif Antibody; anti-Trim69 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
Human Trim69
Purity/Purification
Protein A & Antigen Affinity
Form/Format
Liquid; PBS, pH7.0 with 0.03% Proclin300
Applicable Applications for anti-Trim69 antibody
Immunohistochemistry-Paraffin (IHC-P)
Application Notes
IHC-P: 1:50-1:200
Immunogen
E Coli-derived Human Trim69 fragment
Conjugation
Unconjugated
Preparation
Produced in rabbits immunized with E Coli-derived Human Trim69 fragment, and purified by antigen affinity chromatography.
Preparation and Storage
This antibody can be stored at 2-8 degree C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 degree C to -80 degree C. Avoid repeated freeze-thaw cycles.
Immunohistochemistry (IHC)
(Immunochemical staining of human Trim69 in human testis with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections.)
Immunohistochemistry (IHC)
(Immunochemical staining of human Trim69 in human testis with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections.)
Related Product Information for anti-Trim69 antibody
TRIM69 is a member of the tripartite motif (TRIM) family proteins, which have been reported to participate in various biological processes, such as cell growth, apoptosis, differentiation, innate immune responses, and cancer development. The TRIM family proteins contain a RING finger domain, which may contribute to E3 ubiquitin ligase activity. Several members of the TRIM family proteins (TRIM24, TRIM32, TRIM39, and TRIM59) have been reported to bind and ubiquitylate p53. TRIM69 is evolutionarily conserved in vertebrates. Knockdown of TRIM69 activates the p53 pathway and increases apoptosis during embryogenesis in zebrafish.
References
Rong X, et al. (2019) Trim69 inhibits cataractogenesis by negatively regulating p53. Redox Biol 22 101157.
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Product Notes
The Trim69 (Catalog #AAA8110476) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-Trim69 Antibody, Rabbit Polyclonal reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Trim69 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry-Paraffin (IHC-P). IHC-P: 1:50-1:200. Researchers should empirically determine the suitability of the Trim69 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Trim69, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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