Loading...

Skip to main content

Call us on + 1 (800) 604-9114 for more information about our products

Looking for specific datasheet Manual/COA/MSDS?
Request a Manual/COA/MSDS

Interested to get a quote about our products?
Request a Quote

Western Blot (WB) (Western blot analysis of TMEM107 in THP-1 cell lysate with TMEM107 antibody at 1 μg/ml in (A) the absence and (B) the presence of blocking peptide.)

Rabbit anti-Human TMEM107 Polyclonal Antibody | anti-TMEM107 antibody

TMEM107 Antibody

Gene Names
TMEM107; GRVS638; PRO1268
Reactivity
Human
Applications
ELISA, Western Blot, Immunohistochemistry, Immunofluorescence
Purity
TMEM107 Antibody is affinity chromatography purified via peptide column.
Synonyms
TMEM107; Polyclonal Antibody; TMEM107 Antibody; TMEM107 Antibody : GRVS638; PRO1268; Transmembrane protein 107; transmembrane protein 107; anti-TMEM107 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
TMEM107 antibody is human specific. At least two isoforms of TMEM107 are known to exist.
Purity/Purification
TMEM107 Antibody is affinity chromatography purified via peptide column.
Form/Format
Liquid
Concentration
1 mg/mL (varies by lot)
Sequence Length
146
Applicable Applications for anti-TMEM107 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Application Notes
TMEM107 antibody can be used for detection of TMEM107 by Western blot at 1 - 2 mug/ml.
Conjugate
Unconjugated
Immunogen
TMEM107 antibody was raised against a 19 amino acid peptide near the amino terminus of human TMEM107.
Buffer
TMEM107 Antibody is supplied in PBS containing 0.02% sodium azide.
Preparation and Storage
TMEM107antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year.

Western Blot (WB)

(Western blot analysis of TMEM107 in THP-1 cell lysate with TMEM107 antibody at 1 μg/ml in (A) the absence and (B) the presence of blocking peptide.)

Western Blot (WB) (Western blot analysis of TMEM107 in THP-1 cell lysate with TMEM107 antibody at 1 μg/ml in (A) the absence and (B) the presence of blocking peptide.)

Immunohistochemistry (IHC)

(Immunohistochemistry of TMEM107 in human lymph node tissue with TMEM107 antibody at 5 μg/mL.)

Immunohistochemistry (IHC) (Immunohistochemistry of TMEM107 in human lymph node tissue with TMEM107 antibody at 5 μg/mL.)

Immunofluorescence (IF)

(Immunofluorescence of TMEM107 in human lymph node tissue with TMEM107 antibody at 20 μg/mL.)

Immunofluorescence (IF) (Immunofluorescence of TMEM107 in human lymph node tissue with TMEM107 antibody at 20 μg/mL.)
Related Product Information for anti-TMEM107 antibody
Transmembrane protein 107 (TMEM 107) is critical for cilia formation and embryonic patterning (1). It is a 139 amino acid transmembrane protein encoded by a gene that maps to human chromosome 17 which is associated with two key tumor suppressor genes p53 and BRCA1 (1,2). TMEM107 is required for normal Sonic hedgehog (Shh) signaling in the neural tube and acts in combination with Gli2 and Gli3 to pattern ventral and intermediate neuronal cell types (1,3). TMEM107 is also a strong candidate gene for central areolar choroidal dystrophy (CACD) (1-3).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
Predicted: 16 kDa

Observed: 19kDa
NCBI Official Full Name
transmembrane protein 107 isoform 1
NCBI Official Synonym Full Names
transmembrane protein 107
NCBI Official Symbol
TMEM107
NCBI Official Synonym Symbols
GRVS638; PRO1268
NCBI Protein Information
transmembrane protein 107
UniProt Protein Name
Transmembrane protein 107
Protein Family
UniProt Gene Name
TMEM107
UniProt Entry Name
TM107_HUMAN

Uniprot Description

TMEM107: Plays a role in cilia formation and embryonic patterning. Requires for normal Sonic hedgehog (Shh) signaling in the neural tube and acts in combination with GLI2 and GLI3 to pattern ventral and intermediate neuronal cell types. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, multi-pass; Membrane protein, integral

Chromosomal Location of Human Ortholog: 17p13.1

Cellular Component: integral to membrane

Biological Process: neural tube patterning; cilium biogenesis; embryonic digit morphogenesis

Research Articles on TMEM107

Similar Products

Product Notes

The TMEM107 tmem107 (Catalog #AAA153723) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TMEM107 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's TMEM107 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF). TMEM107 antibody can be used for detection of TMEM107 by Western blot at 1 - 2 mug/ml. Researchers should empirically determine the suitability of the TMEM107 tmem107 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TMEM107, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

Item has been added to Shopping Cart

If you are ready to order, navigate to Shopping Cart and get ready to checkout.

Looking for a specific manual?
Request a Manual

Request more Information

Please complete the form below and a representative will contact you as soon as possible.

Request a Manual

Please complete the form below and a representative will contact you as soon as possible.

Request a Quote

Please complete the form below and a representative will contact you as soon as possible.