Western Blot (WB)
(TM4SF1 Antibody (N-term) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the TM4SF1 antibody detected the TM4SF1 protein (arrow).)
Rabbit anti-Human, mouse TM4SF1 Polyclonal Antibody | anti-TM4SF1 antibody
TM4SF1 Antibody (N-term)
Western Blot (WB)
(TM4SF1 Antibody (N-term) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the TM4SF1 antibody detected the TM4SF1 protein (arrow).)
Western Blot (WB)
(TM4SF1 Antibody (N-term) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the TM4SF1 antibody detected the TM4SF1 protein (arrow).)
Western Blot (WB)
(TM4SF1 Antibody (N-term) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the TM4SF1 antibody detected the TM4SF1 protein (arrow).)
Western Blot (WB)
(TM4SF1 Antibody (N-term) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the TM4SF1 antibody detected the TM4SF1 protein (arrow).)
Immunohistochemistry (IHC)
(TM4SF1 Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human breast carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of TM4SF1 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Immunohistochemistry (IHC)
(TM4SF1 Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human breast carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of TM4SF1 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
transmembrane 4 superfamily, also known as the tetraspanin family.
Most of these members are cell-surface proteins that are
characterized by the presence of four hydrophobic domains. The
proteins mediate signal transduction events that play a role in the
regulation of cell development, activation, growth and motility.
This encoded protein is a cell surface antigen and is highly
expressed in different carcinomas.
Lekishvili, T., et al. J. Cell. Sci. 121 (PT 5), 685-694 (2008) :
Stelzl, U., et al. Cell 122(6):957-968(2005)
Chang, Y.W., et al. Int. J. Cancer 116(2):243-252(2005)
Kao, Y.R., et al. Clin. Cancer Res. 9(7):2807-2816(2003)
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface antigen and is highly expressed in different carcinomas. [provided by RefSeq, Jul 2008]
Uniprot Description
TM4SF1: a multi-pass membrane protein. Member of the transmembrane 4 superfamily, also known as the tetraspanin family. These proteins apparently mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This protein is highly expressed in lung, breast, colon and ovarian carcinomas. It is also present on some normal cells, endothelial cells in particular. Present in high molecular weight complexes in tumor cells.
Protein type: Membrane protein, multi-pass; Membrane protein, integral
Chromosomal Location of Human Ortholog: 3q21-q25
Cellular Component: integral to plasma membrane
Research Articles on TM4SF1
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Product Notes
The TM4SF1 tm4sf1 (Catalog #AAA9209044) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 16-45. The TM4SF1 Antibody (N-term) reacts with Human, mouse and may cross-react with other species as described in the data sheet. AAA Biotech's TM4SF1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC). WB~~1:1000. Researchers should empirically determine the suitability of the TM4SF1 tm4sf1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TM4SF1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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