Rabbit anti-Human, Mouse T4S1 Polyclonal Antibody | anti-T4S1 antibody

T4S1 Antibody

Cat. Num. AAA9407085

• Gene Names: TM4SF1; L6; H-L6; M3S1; TAAL6
• Reactivity: Human, Mouse
• Applications: Immunohistochemistry
• Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Synonyms: T4S1; Polyclonal Antibody; T4S1 Antibody; Transmembrane 4 L6 family member 1; Tumor-associated antigen L6; Membrane component surface marker 1; M3S1; TM4SF1; anti-T4S1 antibody

• Host: Rabbit
• Reactivity: Human, Mouse
• Clonality: Polyclonal
• Specificity: The antibody detects endogenous levels of total T4S1 protein.
• Purity/Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Form/Format: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Concentration: 1.0 mg/ml (varies by lot)
• Sequence Length: 202

• Applicable Applications for anti-T4S1 antibody: Immunohistochemistry (IHC)
• Application Notes: Immunohistochemistry: 1:50~1:100
• Immunogen Type: Peptide
• Immunogen Description: Synthesized peptide derived from internal of human T4S1.
• Target Name: T4S1
• Preparation and Storage: Store at -20 degree C

Immunohistochemistry (IHC)

(Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using T4S1 antibody.)

Related Product Information for anti-T4S1 antibody

The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface antigen and is highly expressed in different carcinomas.Marken J.S., Proc. Natl. Acad. Sci. U.S.A. 89:3503-3507(1992).The MGC Project Team, Genome Res. 14:2121-2127(2004).Marken J.S., J. Biol. Chem. 269:7397-7401(1994).

Product Categories/Family for anti-T4S1 antibody

Total protein Ab

NCBI and Uniprot Product Information

• NCBI GI #: 21265101
• NCBI GeneID: 4071
• NCBI Accession #: NP_055035.1
• NCBI GenBank Nucleotide #: NM_014220.2
• UniProt Accession #: P30408; Q6IB51
• Molecular Weight: 21,632 Da
• NCBI Official Full Name: transmembrane 4 L6 family member 1
• NCBI Official Synonym Full Names: transmembrane 4 L six family member 1
• NCBI Official Symbol: TM4SF1
• NCBI Official Synonym Symbols: L6; H-L6; M3S1; TAAL6
• NCBI Protein Information: transmembrane 4 L6 family member 1
• UniProt Protein Name: Transmembrane 4 L6 family member 1
• UniProt Gene Name: TM4SF1
• UniProt Synonym Gene Names: M3S1; TAAL6
• UniProt Entry Name: T4S1_HUMAN

NCBI Description

The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface antigen and is highly expressed in different carcinomas. [provided by RefSeq, Jul 2008]

Uniprot Description

TM4SF1: a multi-pass membrane protein. Member of the transmembrane 4 superfamily, also known as the tetraspanin family. These proteins apparently mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This protein is highly expressed in lung, breast, colon and ovarian carcinomas. It is also present on some normal cells, endothelial cells in particular. Present in high molecular weight complexes in tumor cells.

Protein type: Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 3q21-q25

Cellular Component: integral to plasma membrane