Western Blot (WB)
(Mouse Tgfbr2 Antibody (C-term) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the Tgfbr2 antibody detected the Tgfbr2 protein (arrow).)
Rabbit anti-Human, mouse Tgfbr2 Polyclonal Antibody | anti-Tgfbr2 antibody
Mouse Tgfbr2 Antibody (C-term)
Western Blot (WB)
(Mouse Tgfbr2 Antibody (C-term) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the Tgfbr2 antibody detected the Tgfbr2 protein (arrow).)
Western Blot (WB)
(Mouse Tgfbr2 Antibody (C-term) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the Tgfbr2 antibody detected the Tgfbr2 protein (arrow).)
Western Blot (WB)
(Mouse Tgfbr2 Antibody (C-term) western blot analysis in mouse spleen tissue lysates (35ug/lane).This demonstrates the Tgfbr2 antibody detected the Tgfbr2 protein (arrow).)
Western Blot (WB)
(Mouse Tgfbr2 Antibody (C-term) western blot analysis in mouse spleen tissue lysates (35ug/lane).This demonstrates the Tgfbr2 antibody detected the Tgfbr2 protein (arrow).)
Robson, A., et al. Dev. Dyn. 239(9):2435-2442(2010)
Moreno, S.G., et al. Dev. Biol. 342(1):74-84(2010)
Ouyang, W., et al. Immunity 32(5):642-653(2010)
Lu, L., et al. J. Immunol. 184(8):4295-4306(2010)
NCBI and Uniprot Product Information
Uniprot Description
TGFBR2: a TKL kinase of the serine/threonine-protein kinase receptor (STKR) family. R1 and R2 TGF-beta receptors dimerize after binding TGF-beta at the cell surface. Binds to DAXX. Defects can cause esophageal cancer.
Protein type: Oncoprotein; Protein kinase, Ser/Thr (receptor); Membrane protein, integral; Kinase, protein; Protein kinase, TKL; EC 2.7.11.30; TKL group; STKR family; Type2 subfamily
Cellular Component: cell surface; membrane; integral to plasma membrane; cytoplasm; plasma membrane; integral to membrane; caveola; cytosol; receptor complex; external side of plasma membrane; lipid raft
Molecular Function: glycosaminoglycan binding; metal ion binding; nucleotide binding; receptor activity; mitogen-activated protein kinase kinase kinase binding; transmembrane receptor protein serine/threonine kinase activity; protein kinase activity; transforming growth factor beta receptor activity; transferase activity; protein serine/threonine kinase activity; protein binding; transforming growth factor beta receptor activity, type II; transforming growth factor beta binding; transferase activity, transferring phosphorus-containing groups; kinase activity; SMAD binding; ATP binding; receptor signaling protein serine/threonine kinase activity
Biological Process: lens development in camera-type eye; apoptosis; positive regulation of smooth muscle cell proliferation; heart development; myeloid dendritic cell differentiation; gastrulation; palate development; positive regulation of tolerance induction to self antigen; protein amino acid phosphorylation; negative regulation of cell proliferation; negative regulation of cardiac muscle cell proliferation; transforming growth factor beta receptor signaling pathway; regulation of growth; transmembrane receptor protein serine/threonine kinase signaling pathway; positive regulation of mesenchymal cell proliferation; positive regulation of NK T cell differentiation; vasculogenesis; cell differentiation; positive regulation of T cell tolerance induction; response to drug; receptor-mediated endocytosis; smoothened signaling pathway; embryonic hemopoiesis; in utero embryonic development; common-partner SMAD protein phosphorylation; peptidyl-threonine phosphorylation; embryonic cranial skeleton morphogenesis; regulation of cell proliferation; patterning of blood vessels; peptidyl-serine phosphorylation; positive regulation of angiogenesis; organ morphogenesis; regulation of gene expression; cartilage development; positive regulation of B cell tolerance induction; activation of protein kinase activity; brain development; phosphorylation; lung development
Research Articles on Tgfbr2
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Product Notes
The Tgfbr2 tgfbr2 (Catalog #AAA9211747) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 548-575. The Mouse Tgfbr2 Antibody (C-term) reacts with Human, mouse and may cross-react with other species as described in the data sheet. AAA Biotech's Tgfbr2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the Tgfbr2 tgfbr2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Tgfbr2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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