Western Blot (WB)
(Western blot analysis of Plxdc2 in human colon tissue lysate with Plxdc2 antibody at (A) 0.5 (B) 1 ug/ml.)
Rabbit TEM7R Polyclonal Antibody
TEM7R, CT (Plxdc2, Plexin domain-containing protein 2, Tumor endothelial marker 7-related protein)
Reactivity
Human, Mouse, Rat
Applications
Western Blot
Purity
Affinity PurifiedPurified by immunoaffinity chromatography.
Synonyms
TEM7R; Polyclonal Antibody; CT (Plxdc2; Plexin domain-containing protein 2; Tumor endothelial marker 7-related protein); Anti -TEM7R; anti-TEM7R antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes human Plxdc2. Species crossreactivity: Mouse and rat.
Purity/Purification
Affinity Purified
Purified by immunoaffinity chromatography.
Purified by immunoaffinity chromatography.
Form/Format
Supplied as a liquid in PBS, 0.02% sodium azide.
Applicable Applications for anti-TEM7R antibody
Western Blot (WB)
Application Notes
Suitable for use in Western Blot.
Dilution: Western Blot: 0.5-1ug/ml
Dilution: Western Blot: 0.5-1ug/ml
Immunogen
Synthetic peptide corresponding to 17aa from near the carboxy terminus of human Plxdc2 (GenBank accession no. Q6UX71).
Preparation and Storage
May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Western Blot (WB)
(Western blot analysis of Plxdc2 in human colon tissue lysate with Plxdc2 antibody at (A) 0.5 (B) 1 ug/ml.)
Western Blot (WB)
(Western blot analysis of Plxdc2 in human colon tissue lysate with Plxdc2 antibody at (A) 0.5 (B) 1 ug/ml.)
Related Product Information for anti-TEM7R antibody
Plxdc2, also known as Tumor endothelial marker 7-related (TEM7R) encodes a protein with 57% amino acid identity to TEM7, the most abundant tumor endothelial marker (1,2). Plxdc2 is strongly expressed in the endothelial cells of the tumor stroma, but not in the endothelial cells of normal colonic tissue. Plxdc2 is also expressed at high levels in vessels of some normal tissues, with highest expression in muscle and lung (1). Plxdc2 and TEM7 may be important for tumor angiogenesis in humans (2,3). Cortactin was identified as a protein capable of binding to the extracellular region of both TEM7 and Plxdc2, and may provide new opportunities for the delivery of therapeutic and imaging agents to the vessels of solid tumors (4).
Product Categories/Family for anti-TEM7R antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI Official Full Name
tumor endothelial marker 7-related
Uniprot Description
PLXDC2: May play a role in tumor angiogenesis. Belongs to the plexin family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral
Chromosomal Location of Human Ortholog: 10p12.31
Cellular Component: integral to membrane
Molecular Function: protein binding; receptor activity
Biological Process: multicellular organismal development
Similar Products
Product Notes
The TEM7R (Catalog #AAA619520) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TEM7R, CT (Plxdc2, Plexin domain-containing protein 2, Tumor endothelial marker 7-related protein) reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's TEM7R can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Suitable for use in Western Blot. Dilution: Western Blot: 0.5-1ug/ml. Researchers should empirically determine the suitability of the TEM7R for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TEM7R, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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