Western Blot (WB)
(Western blot analysis of TEM7 in human liver tissue lysate with TEM7 antibody at (A) 0.5, (B) 1 and (C) 2 ug/mL.)
Rabbit TEM7 Polyclonal Antibody | anti-TEM7 antibody
TEM7 Antibody
Reactivity
Human, Mouse, Rat
Applications
ELISA, Western Blot, Immunohistochemistry
Purity
Affinity chromatography purified via peptide column
Synonyms
TEM7; Polyclonal Antibody; TEM7 Antibody; Tumor endothelial marker 7; TEM3; plexin domain-containing protein 1; PLXDC1; anti-TEM7 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Purity/Purification
Affinity chromatography purified via peptide column
Form/Format
Supplied in PBS containing 0.02% sodium azide.
Sequence Length
500
Applicable Applications for anti-TEM7 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Immunogen Type
Peptide
Immunogen Description
Raised against a 16 amino acid peptide from near the carboxy terminus of human TEM7.
Target Name
TEM7
Preparation and Storage
Can be stored at -20 degree C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Western Blot (WB)
(Western blot analysis of TEM7 in human liver tissue lysate with TEM7 antibody at (A) 0.5, (B) 1 and (C) 2 ug/mL.)
Western Blot (WB)
(Western blot analysis of TEM7 in human liver tissue lysate with TEM7 antibody at (A) 0.5, (B) 1 and (C) 2 ug/mL.)
Immunohistochemistry (IHC)
(Immunohistochemistry of TEM7 in mouse liver tissue with TEM7 antibody at 2.5 ug/mL.)
Immunohistochemistry (IHC)
(Immunohistochemistry of TEM7 in mouse liver tissue with TEM7 antibody at 2.5 ug/mL.)
Related Product Information for anti-TEM7 antibody
Tumor endothelial marker 7 (TEM7) was identified through serial analysis of gene expression on endothelial cells isolated from human normal and malignant colorectal tissues. Further experiments verified TEM7 was highly expressed in the endothelium of numerous other cancer types including breast, lung and brain tumors. At least four isoforms of TEM7 are known to exist; these include intracellular, secreted, and membrane-bound forms. A homologous protein, TEM7R (also known as PLXDC2), acts as a binding partner to TEM7 and is also abundantly expressed in the endothelium of malignant colorectal cancer but is absent or rare in normal colon mucosa. High expression of TEM7 is associated with metastasis and poor survival of patients with osteogenic sarcoma.
Product Categories/Family for anti-TEM7 antibody
NCBI and Uniprot Product Information
NCBI GI #
Molecular Weight
47,895 Da
NCBI Official Full Name
tumor endothelial marker 7
UniProt Protein Name
Plexin domain-containing protein 1
UniProt Gene Name
PLXDC1
UniProt Synonym Gene Names
TEM3; TEM7
UniProt Entry Name
PLDX1_HUMAN
Uniprot Description
PLXDC1: Plays a critical role in endothelial cell capillary morphogenesis. Belongs to the plexin family. 4 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral; Cell surface
Chromosomal Location of Human Ortholog: 17q21.1
Cellular Component: extracellular space; tight junction; cell soma; dendrite; cytoplasm; integral to membrane; extracellular region; plasma membrane; intracellular; receptor complex
Molecular Function: protein binding; receptor activity
Biological Process: spinal cord development; angiogenesis
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Product Notes
The TEM7 plxdc1 (Catalog #AAA9402321) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TEM7 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's TEM7 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). Researchers should empirically determine the suitability of the TEM7 plxdc1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TEM7, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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