Testing Data
Rabbit anti-Human TDRD12-BD2 Polyclonal Antibody | anti-TDRD12-BD2 antibody
TDRD12-BD2 Antibody
Gene Names
TDRD12; ECAT8
Reactivity
Human
Applications
Western Blot
Purity
Affinity Purified Antibody
Synonyms
TDRD12-BD2; Polyclonal Antibody; TDRD12-BD2 Antibody; ECAT8; anti-TDRD12-BD2 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity Purified Antibody
Form/Format
100 ug (0.5 mg/ml) of antibody in PBS pH 7.2 containing 0.01 % BSA, 0.01 % thimerosal, and 50 % glycerol.
Appearance: Colorless liquid
Appearance: Colorless liquid
Concentration
0.5 mg/ml (varies by lot)
Sequence Length
395
Applicable Applications for anti-TDRD12-BD2 antibody
Western Blot (WB)
Application Notes
Western blot: 1-4 ug/ml.
Immunogen
Recombinant human TDRD12-BD2
Positive Control
Western Blot: Recombinant protein
Handling
The antibody solution should be gently mixed before use.
Preparation and Storage
At -20 degree C
Shelf Life: 12 months
Shelf Life: 12 months
Testing Data
Testing Data
Related Product Information for anti-TDRD12-BD2 antibody
Polyclonal Antibody to detect TDRD12-BD2 in human samples
Background: Tudor domains are small protein structural motifs of about ~50 amino acids related to the "royal family" of methyl readers, which also includes chromo, MBT, PWWP, and Agenet-like domains. Tudor domains occur either alone, in tandem, or with other domains and are found in many proteins that are involved in RNA metabolism, germ cell development, transposon silencing, DNA damage response, histone modification, and chromatin remodeling. The tudor domains recognize symmetric methylated arginine or methylated lysine residues. Tudor domain proteins act as an oncogene and play a very important role in HCC and colon cancer. TDRD is also involved in RISC complex and interacts with AEG-1 oncogene. The tudor domain can bind to methylated arginine protein and promote tumor angiogenesis in human hepatocellular carcinoma, etc.
Background: Tudor domains are small protein structural motifs of about ~50 amino acids related to the "royal family" of methyl readers, which also includes chromo, MBT, PWWP, and Agenet-like domains. Tudor domains occur either alone, in tandem, or with other domains and are found in many proteins that are involved in RNA metabolism, germ cell development, transposon silencing, DNA damage response, histone modification, and chromatin remodeling. The tudor domains recognize symmetric methylated arginine or methylated lysine residues. Tudor domain proteins act as an oncogene and play a very important role in HCC and colon cancer. TDRD is also involved in RISC complex and interacts with AEG-1 oncogene. The tudor domain can bind to methylated arginine protein and promote tumor angiogenesis in human hepatocellular carcinoma, etc.
Product Categories/Family for anti-TDRD12-BD2 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
45,033 Da
NCBI Official Full Name
putative ATP-dependent RNA helicase TDRD12
NCBI Official Synonym Full Names
tudor domain containing 12
NCBI Official Symbol
TDRD12
NCBI Official Synonym Symbols
ECAT8
NCBI Protein Information
putative ATP-dependent RNA helicase TDRD12
UniProt Protein Name
Putative ATP-dependent RNA helicase TDRD12
UniProt Gene Name
TDRD12
UniProt Synonym Gene Names
ECAT8
UniProt Entry Name
TDR12_HUMAN
Uniprot Description
TDRD12: 2 isoforms of the human protein are produced by alternative splicing.
Protein type: EC 3.6.4.13
Chromosomal Location of Human Ortholog: 19q13.11
Molecular Function: nucleic acid binding; helicase activity; ATP binding
Biological Process: fertilization; multicellular organismal development; DNA methylation during gametogenesis; spermatogenesis; gene expression; RNA-mediated gene silencing; male meiosis; cell differentiation
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Product Notes
The TDRD12-BD2 tdrd12 (Catalog #AAA841367) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TDRD12-BD2 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's TDRD12-BD2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Western blot: 1-4 ug/ml. Researchers should empirically determine the suitability of the TDRD12-BD2 tdrd12 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TDRD12-BD2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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