Testing Data
TDRD12-BD2 Recombinant Protein | TDRD12 recombinant protein
TDRD12-BD2 (908-999 aa) (His-Tagged), human recombinant
Gene Names
TDRD12; ECAT8
Purity
>=98% by SDS-PAGE.
Synonyms
TDRD12-BD2; TDRD12-BD2 (908-999 aa) (His-Tagged); human recombinant; ECAT8; TDRD12 recombinant protein
Host
E Coli
Purity/Purification
>=98% by SDS-PAGE.
Form/Format
Liquid
rh-TDRD12-BD2 is supplied as a solution (2mg/mL) in PBS Buffer containing 10% glycerol
rh-TDRD12-BD2 is supplied as a solution (2mg/mL) in PBS Buffer containing 10% glycerol
Sequence Positions
908-999
Sequence Length
395
Application and USAGE
TDRD12 is useful in studying bromodomain binding assays,screening inibitors and selectivity profiling.
Preparation and Storage
Stable for 1 year at -80°C. Avoid multiple freeze/thaw cycles as activity may decrease.
Ships with dry ice.
Ships with dry ice.
Testing Data
Testing Data
Related Product Information for TDRD12 recombinant protein
Background: Tudor domains are small protein structural motifs of about ~50 amino acids related to the "royal family" of methyl readers, which also includes chromo, MBT, PWWP, and Agenet-like domains. Tudor domains occur either alone, in tandem, or with other domains and are found in many proteins that are involved in RNA metabolism, germ cell development, transposon silencing, DNA damage response, histone modification, and chromatin remodeling. The tudor domains recognize symmetric methylated arginine or methylated lysine residues. Tudor domain proteins act as an oncogene and play a very important role in HCC and colon cancer. TDRD is also involved in RISC complex and interacts with AEG-1 oncogene. The tudor domain can bind to methylated arginine protein and promote tumor angiogenesis in human hepatocellular carcinoma, etc. The recombinant protein includes TDRD12 (domain 908-999aa) with N-terminal His-tag.
Product Categories/Family for TDRD12 recombinant protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
13 kDa (91 aa, 908-999 aa+ NT 6X His Tag)
NCBI Official Full Name
putative ATP-dependent RNA helicase TDRD12
NCBI Official Synonym Full Names
tudor domain containing 12
NCBI Official Symbol
TDRD12
NCBI Official Synonym Symbols
ECAT8
NCBI Protein Information
putative ATP-dependent RNA helicase TDRD12
UniProt Protein Name
Putative ATP-dependent RNA helicase TDRD12
Protein Family
UniProt Gene Name
TDRD12
UniProt Synonym Gene Names
ECAT8
UniProt Entry Name
TDR12_HUMAN
Uniprot Description
TDRD12: 2 isoforms of the human protein are produced by alternative splicing.
Protein type: EC 3.6.4.13
Chromosomal Location of Human Ortholog: 19q13.11
Molecular Function: nucleic acid binding; helicase activity; ATP binding
Biological Process: fertilization; multicellular organismal development; DNA methylation during gametogenesis; spermatogenesis; RNA-mediated gene silencing; gene expression; male meiosis; cell differentiation
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Product Notes
The TDRD12 tdrd12 (Catalog #AAA845223) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 908-999. It is sometimes possible for the material contained within the vial of "TDRD12-BD2, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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