Testing Data
Rabbit anti-Human Wnt-2 Polyclonal Antibody | anti-Wnt-2 antibody
Wnt-2 Antibody
Appearance: Colorless liquid
Shelf Life: 12 months
Testing Data
Testing Data
Background: This protein belongs to the Wnt family of proteins. The WNT gene family consists of structurally related genes that encode secreted signaling proteins involved in the Wnt signaling pathway. Wnt gene family members, including Wnt-1 through Wnt-10, play a key role in regulating cellular growth and differentiation. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. Wnt-2 is expressed in brain in the thalamus, in fetal and adult lung and in the placenta.
NCBI and Uniprot Product Information
NCBI Description
This gene is a member of the WNT gene family. The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. Alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, Jul 2008]
Uniprot Description
WNT2: Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters. Belongs to the Wnt family.
Protein type: Cell adhesion; Secreted, signal peptide; Extracellular matrix; Secreted; Cell development/differentiation
Chromosomal Location of Human Ortholog: 7q31.2
Cellular Component: extracellular matrix; proteinaceous extracellular matrix; extracellular space; cytoplasm; plasma membrane; extracellular region
Molecular Function: protein binding; frizzled binding; cytokine activity; receptor agonist activity
Biological Process: lens development in camera-type eye; Wnt receptor signaling pathway; cell fate commitment; atrial cardiac muscle morphogenesis; Wnt receptor signaling pathway through beta-catenin; neuron differentiation; positive regulation of fibroblast proliferation; cell-cell signaling; positive regulation of cell proliferation; positive regulation of mesenchymal cell proliferation; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription factor activity; positive regulation of endothelial cell proliferation; positive regulation of cardiac muscle cell proliferation; lung development
Research Articles on Wnt-2
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Product Notes
The Wnt-2 wnt2 (Catalog #AAA840919) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Wnt-2 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Wnt-2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Western blot: 1-4 ug/ml. Researchers should empirically determine the suitability of the Wnt-2 wnt2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Wnt-2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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