Western Blot (WB)
(Western blot analysis of extracts from Mouse spleen tissue, using Syntaxin7 Antibody. The lane on the left was treated with blocking peptide.)
Rabbit Syntaxin7 Polyclonal Antibody | anti-STX7 antibody
Syntaxin7 Antibody
Predicted: Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken
Predicted: Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken
Western Blot (WB)
(Western blot analysis of extracts from Mouse spleen tissue, using Syntaxin7 Antibody. The lane on the left was treated with blocking peptide.)
Western Blot (WB)
(Western blot analysis of extracts from Mouse spleen tissue, using Syntaxin7 Antibody. The lane on the left was treated with blocking peptide.)
Subunit Structure: Forms a SNARE complex with VTI1B, STX8 and VAMP8 which functions in the homotypic fusion of late endosomes. Component of the SNARE complex composed of STX7, STX8, VAMP7 and VTI1B that is required for heterotypic fusion of late endosomes with lysosomes (By similarity). Interacts with VPS11, VPS16 and VPS18. Interacts with VPS33A.
Similarity: Belongs to the syntaxin family.
NCBI and Uniprot Product Information
Predicted: 30 kDa
NCBI Description
The protein encoded by this gene is a syntaxin family membrane receptor involved in vesicle transport. The encoded protein binds alpha-SNAP, an important regulator of transport vesicle fusion. Along with syntaxin 13, this protein plays a role in the ordered fusion of endosomes and lysosomes with the phagosome. [provided by RefSeq, May 2016]
Uniprot Description
STX7: May be involved in protein trafficking from the plasma membrane to the early endosome (EE) as well as in homotypic fusion of endocytic organelles. Mediates the endocytic trafficking from early endosomes to late endosomes and lysosomes. Belongs to the syntaxin family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Vesicle; Membrane protein, integral
Chromosomal Location of Human Ortholog: 6q23.1
Cellular Component: intracellular membrane-bound organelle; lysosomal membrane; lysosome; early endosome; integral to membrane; immunological synapse; endomembrane system; SNARE complex; azurophil granule; recycling endosome; endocytic vesicle; perinuclear region of cytoplasm; early endosome membrane; late endosome; plasma membrane; vesicle; endosome
Molecular Function: SNAP receptor activity; SNARE binding; chloride channel inhibitor activity; syntaxin binding
Biological Process: vesicle fusion; intracellular protein transport; organelle localization; vesicle docking; positive regulation of T cell mediated cytotoxicity
Research Articles on STX7
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Product Notes
The STX7 stx7 (Catalog #AAA9611513) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Syntaxin7 Antibody reacts with Human, Mouse, Rat Predicted: Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken and may cross-react with other species as described in the data sheet. AAA Biotech's Syntaxin7 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500-1:2000. Researchers should empirically determine the suitability of the STX7 stx7 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Syntaxin7, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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