Western Blot (WB)
(Western blot analysis of extracts from HepG2 cells, using VPS45 Antibody. The lane on the left was treated with blocking peptide.)
Rabbit VPS45 Polyclonal Antibody | anti-VPS45 antibody
VPS45 Antibody
Predicted: Pig, Zebrafish, Bovine, Horse, Sheep, Dog, Xenopus
Predicted: Pig, Zebrafish, Bovine, Horse, Sheep, Dog, Xenopus
Western Blot (WB)
(Western blot analysis of extracts from HepG2 cells, using VPS45 Antibody. The lane on the left was treated with blocking peptide.)
Western Blot (WB)
(Western blot analysis of extracts from HepG2 cells, using VPS45 Antibody. The lane on the left was treated with blocking peptide.)
Subunit Structure: Interacts with STX6 (By similarity). Interacts with ZFYVE20.
Similarity: Belongs to the STXBP/unc-18/SEC1 family.
NCBI and Uniprot Product Information
Predicted: 66 kDa
NCBI Description
Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene is a member of the Sec1 domain family, and shows a high degree of sequence similarity to mouse, rat and yeast Vps45. The exact function of this gene is not known, but its high expression in peripheral blood mononuclear cells suggests a role in trafficking proteins, including inflammatory mediators. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2013]
Uniprot Description
VPS45A: May play a role in vesicle-mediated protein trafficking from the Golgi stack through the trans-Golgi network. Belongs to the STXBP/unc-18/SEC1 family.
Protein type: Vesicle
Chromosomal Location of Human Ortholog: 1q21.2
Cellular Component: Golgi membrane; Golgi apparatus; integral to membrane; endosome membrane
Biological Process: intracellular protein transport; blood coagulation; vesicle docking during exocytosis
Disease: Neutropenia, Severe Congenital, 5, Autosomal Recessive
Research Articles on VPS45
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Product Notes
The VPS45 vps45 (Catalog #AAA9611547) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The VPS45 Antibody reacts with Human, Mouse, Rat Predicted: Pig, Zebrafish, Bovine, Horse, Sheep, Dog, Xenopus and may cross-react with other species as described in the data sheet. AAA Biotech's VPS45 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500-1:2000. Researchers should empirically determine the suitability of the VPS45 vps45 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "VPS45, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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