Immunohistochemistry (IHC)
(Anti-STK17B / DRAK2 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)
Rabbit anti-Human STK17B / DRAK2 Polyclonal Antibody | anti-STK17B antibody
Rabbit Polyclonal to Human STK17B / DRAK2
Gene Names
STK17B; DRAK2
Reactivity
Human
Applications
Immunohistochemistry, Immunocytochemistry, Western Blot
Purity
Ion exchange Chromatography
Synonyms
STK17B / DRAK2; Polyclonal Antibody; Rabbit Polyclonal to Human STK17B / DRAK2; Anti-STK17B / DRAK2 Antibody (aa351-365) IHC-plus; STK17B; DRAK2; Serine/threonine kinase 17b; Human STK17B; anti-STK17B antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Specificity
peptide corresponding to amino acids 351 to 365 of human DRAK2
Purity/Purification
Ion exchange Chromatography
Form/Format
PBS, 0.02% sodium azide.
Concentration
0.5 mg/ml (varies by lot)
Sequence Length
372
Applicable Applications for anti-STK17B antibody
Immunohistochemistry (IHC - Paraffin), Immunocytochemistry (ICC), Western Blot (WB)
Application Notes
ICC, IHC-P (5 ug/ml), WB (1:500 - 1:1000)
Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antib...
Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antib...
Target Species
Human
Immunogen Description
Synthetic peptide from human STK17B / DRAK2.
Immunogen Type
Synthetic peptide
Immunogen
STK17B / DRAK2 antibody was raised against synthetic peptide from human STK17B / DRAK2.
Antigen Modification
aa351-365
Preparation and Storage
Short term 4 degree C, long term aliquot and store at -20 degree C, avoid freeze thaw cycles. Store undiluted.
Immunohistochemistry (IHC)
(Anti-STK17B / DRAK2 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)
Immunohistochemistry (IHC)
(Anti-STK17B / DRAK2 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)
Immunocytochemistry (ICC)
(Immunocytochemistry of DRAK2 in Jurkat cells with DRAK2 antibody at 10 ug/ml.)
Immunocytochemistry (ICC)
(Immunocytochemistry of DRAK2 in Jurkat cells with DRAK2 antibody at 10 ug/ml.)
Western Blot (WB)
(Western blot of DRAK2 in Jurkat (1,3) and Raji (2,4) cell lysate in the absence (1,2) or presence (3,4) of blocking peptide with DRAK2 antibody at 1:500 dilution.)
Western Blot (WB)
(Western blot of DRAK2 in Jurkat (1,3) and Raji (2,4) cell lysate in the absence (1,2) or presence (3,4) of blocking peptide with DRAK2 antibody at 1:500 dilution.)
Related Product Information for anti-STK17B antibody
STK17B, a DAPK type protein kinase, functions in apoptotic signaling. In vitro assays have shown that protein is autophosphorylated. Messanger RNAs of various in sizes have been reported, likely due to differences of 3' untranslated region.
Product Categories/Family for anti-STK17B antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
42,344 Da
NCBI Official Full Name
serine/threonine-protein kinase 17B
NCBI Official Synonym Full Names
serine/threonine kinase 17b
NCBI Official Symbol
STK17B
NCBI Official Synonym Symbols
DRAK2
NCBI Protein Information
serine/threonine-protein kinase 17B; death-associated protein kinase-related 2; DAP kinase-related apoptosis-inducing protein kinase 2
UniProt Protein Name
Serine/threonine-protein kinase 17B
Protein Family
UniProt Gene Name
STK17B
UniProt Synonym Gene Names
DRAK2
UniProt Entry Name
ST17B_HUMAN
Uniprot Description
DRAK2: a calmodulin-dependent kinase of the DAPK family. Interacts with and is regulated by calcineurin homologous protein (CHP), an EF-hand Ca(2+)-binding protein. In vitro, CHP inhibits the apoptosis-inducing protein kinase DRAK2 in the presence of elevated Ca(2+) levels. Highly expressed in placenta, lung, pancreas. Lower levels in heart, brain, liver, skeletal muscle and kidney.
Protein type: Kinase, protein; EC 2.7.11.1; Protein kinase, Ser/Thr (non-receptor); Protein kinase, CAMK; CAMK group; DAPK family
Chromosomal Location of Human Ortholog: 2q32.3
Cellular Component: plasma membrane; ER-Golgi intermediate compartment; nucleus; actin cytoskeleton
Molecular Function: protein serine/threonine kinase activity; ATP binding; protein kinase activity
Biological Process: apoptosis; protein amino acid autophosphorylation; protein amino acid phosphorylation
Research Articles on STK17B
Similar Products
Product Notes
The STK17B stk17b (Catalog #AAA240325) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit Polyclonal to Human STK17B / DRAK2 reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's STK17B / DRAK2 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC - Paraffin), Immunocytochemistry (ICC), Western Blot (WB). ICC, IHC-P (5 ug/ml), WB (1:500 - 1:1000) Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antib.. Researchers should empirically determine the suitability of the STK17B stk17b for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "STK17B / DRAK2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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