Loading...

Skip to main content

Call us on + 1 (800) 604-9114 for more information about our products

Looking for specific datasheet Manual/COA/MSDS?
Request a Manual/COA/MSDS

Interested to get a quote about our products?
Request a Quote

Immunohistochemistry (IHC) (Anti-STK17A / DRAK1 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)

Mouse anti-Human DRAK1 / STK17A Monoclonal Antibody | anti-DRAK1 antibody

Mouse Monoclonal [clone 4D12] (IgG2a,k) to Human DRAK1 / STK17A

Gene Names
STK17A; DRAK1
Reactivity
Human
Applications
Immunohistochemistry, Western Blot, ELISA
Purity
Protein A Purified
Synonyms
DRAK1 / STK17A; Monoclonal Antibody; Mouse Monoclonal [clone 4D12] (IgG2a; k) to Human DRAK1 / STK17A; Anti-DRAK1 / STK17A Antibody (clone 4D12) IHC-plus; STK17A; DRAK1; Serine/threonine kinase 17a; Human DRAK1; anti-DRAK1 antibody
Ordering
For Research Use Only!
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG2a,k
Clone Number
4D12
Purity/Purification
Protein A Purified
Form/Format
PBS, pH 7.4. Sourced in Ascites.
Concentration
0.23 mg/ml (varies by lot)
Sequence Length
414
Applicable Applications for anti-DRAK1 antibody
Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA), RNA interference
Application Notes
ELISA, IHC-P (5 ug/ml), RNAi, WB
Usage: Western Blot (Cell lysate) - positive control HepG2. Western Blot (Transfected lysate) - positive control transfected 293T cell line. Sandwich ELISA (Recombinant protein). RNAi Knockdown (Antibody validated).
Target Species
Human
Immunogen Description
STK17A (AAH47696, 301 a.a. ~ 414 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Immunogen Type
Recombinant protein
Immunogen
DRAK1 / STK17A antibody was raised against sTK17A (AAH47696, 301 a.a. ~ 414 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Preparation and Storage
Store at -20 degree C. Aliquot to avoid freeze/thaw cycles.

Immunohistochemistry (IHC)

(Anti-STK17A / DRAK1 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)

Immunohistochemistry (IHC) (Anti-STK17A / DRAK1 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)

Immunohistochemistry (IHC)

(Anti-STK17A / DRAK1 antibody IHC of human uterus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)

Immunohistochemistry (IHC) (Anti-STK17A / DRAK1 antibody IHC of human uterus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)

Western Blot (WB)

(STK17A monoclonal antibody clone 4D12 Western blot of STK17A expression in HepG2.)

Western Blot (WB) (STK17A monoclonal antibody clone 4D12 Western blot of STK17A expression in HepG2.)

ELISA (EIA)

(Detection limit for recombinant GST tagged STK17A is approximately 0.1 ng/ml as a capture antibody.)

ELISA (EIA) (Detection limit for recombinant GST tagged STK17A is approximately 0.1 ng/ml as a capture antibody.)
Related Product Information for anti-DRAK1 antibody
STK17A, a DAPK type protein kinase, functions in apoptotic signaling. The catalytic domain is similar to that of other members of this subfamily, and the noncatalytic C-terminus is responsible for regulation of kinase activity. In vitro assays have shown that protein is autophosphorylated.
Product Categories/Family for anti-DRAK1 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
46,558 Da
NCBI Official Full Name
serine/threonine-protein kinase 17A
NCBI Official Synonym Full Names
serine/threonine kinase 17a
NCBI Official Symbol
STK17A
NCBI Official Synonym Symbols
DRAK1
NCBI Protein Information
serine/threonine-protein kinase 17A; death-associated protein kinase-related 1; serine/threonine kinase 17a (apoptosis-inducing); DAP kinase-related apoptosis-inducing protein kinase 1
UniProt Protein Name
Serine/threonine-protein kinase 17A
UniProt Gene Name
STK17A
UniProt Synonym Gene Names
DRAK1
UniProt Entry Name
ST17A_HUMAN

NCBI Description

This gene is a member of the DAP kinase-related apoptosis-inducing protein kinase family and encodes an autophosphorylated nuclear protein with a protein kinase domain. The protein has apoptosis-inducing activity. [provided by RefSeq, Jul 2008]

Uniprot Description

DRAK1: a calmodulin-dependent kinase of the DAPK family. Interacts with and is regulated by calcineurin homologous protein (CHP), an EF-hand Ca(2+)-binding protein. In vitro, CHP inhibits the apoptosis-inducing protein kinase DRAK2 in the presence of elevated Ca(2+) levels. Highly expressed in placenta, lung, pancreas. Lower levels in heart, brain, liver, skeletal muscle and kidney.

Protein type: Protein kinase, CAMK; EC 2.7.11.1; Protein kinase, Ser/Thr (non-receptor); Kinase, protein; CAMK group; DAPK family

Chromosomal Location of Human Ortholog: 7p13

Cellular Component: nucleus

Molecular Function: protein serine/threonine kinase activity; ATP binding

Biological Process: apoptosis; positive regulation of apoptosis; protein amino acid phosphorylation

Research Articles on DRAK1

Similar Products

Product Notes

The DRAK1 stk17a (Catalog #AAA246381) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Mouse Monoclonal [clone 4D12] (IgG2a,k) to Human DRAK1 / STK17A reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's DRAK1 / STK17A can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA), RNA interference. ELISA, IHC-P (5 ug/ml), RNAi, WB Usage: Western Blot (Cell lysate) - positive control HepG2. Western Blot (Transfected lysate) - positive control transfected 293T cell line. Sandwich ELISA (Recombinant protein). RNAi Knockdown (Antibody validated). Researchers should empirically determine the suitability of the DRAK1 stk17a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DRAK1 / STK17A, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

Item has been added to Shopping Cart

If you are ready to order, navigate to Shopping Cart and get ready to checkout.

Looking for a specific manual?
Request a Manual

Request more Information

Please complete the form below and a representative will contact you as soon as possible.

Request a Manual

Please complete the form below and a representative will contact you as soon as possible.

Request a Quote

Please complete the form below and a representative will contact you as soon as possible.