Western Blot (WB)
(RBMS1 Antibody (Center) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the RBMS1 antibody detected the RBMS1 protein (arrow).)
Rabbit anti-Human RBMS1 Polyclonal Antibody | anti-RBMS1 antibody
RBMS1 Antibody (Center)
Western Blot (WB)
(RBMS1 Antibody (Center) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the RBMS1 antibody detected the RBMS1 protein (arrow).)
Western Blot (WB)
(RBMS1 Antibody (Center) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the RBMS1 antibody detected the RBMS1 protein (arrow).)
which bind single stranded DNA/RNA. These proteins are
characterized by the presence of two sets of ribonucleoprotein
consensus sequence (RNP-CS) that contain conserved motifs, RNP1 and
RNP2, originally described in RNA binding proteins, and required
for DNA binding. These proteins have been implicated in such
diverse functions as DNA replication, gene transcription, cell
cycle progression and apoptosis. Several transcript variants,
resulting from alternative splicing and encoding different
isoforms, have been described. A pseudogene for this locus is found
on chromosome 12.
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Landers, J.E., et al. Proc. Natl. Acad. Sci. U.S.A. 106(22):9004-9009(2009)
Sugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007)
Lamesch, P., et al. Genomics 89(3):307-315(2007)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of a small family of proteins which bind single stranded DNA/RNA. These proteins are characterized by the presence of two sets of ribonucleoprotein consensus sequence (RNP-CS) that contain conserved motifs, RNP1 and RNP2, originally described in RNA binding proteins, and required for DNA binding. These proteins have been implicated in such diverse functions as DNA replication, gene transcription, cell cycle progression and apoptosis. Several transcript variants, resulting from alternative splicing and encoding different isoforms, have been described. A pseudogene for this locus is found on chromosome 12. [provided by RefSeq, Feb 2009]
Uniprot Description
RBMS1: Single-stranded DNA binding protein that interacts with the region upstream of the MYC gene. Binds specifically to the DNA sequence motif 5'-[AT]CT[AT][AT]T-3'. Probably has a role in DNA replication. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: RNA-binding; DNA replication
Chromosomal Location of Human Ortholog: 2q24.2
Cellular Component: nucleus
Molecular Function: protein binding; RNA binding; double-stranded DNA binding; nucleotide binding; single-stranded DNA binding
Biological Process: RNA processing; DNA replication
Research Articles on RBMS1
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Product Notes
The RBMS1 rbms1 (Catalog #AAA9202176) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 224-252. The RBMS1 Antibody (Center) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's RBMS1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the RBMS1 rbms1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "RBMS1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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