Rabbit anti-Human RBMS1 Polyclonal Antibody | anti-RBMS1 antibody

RBMS1 (RNA-binding Motif, Single-stranded-interacting Protein 1, Single-stranded DNA-binding Protein MSSP-1, Suppressor of CDC2 with RNA-binding Motif 2, C2orf12, MSSP, MSSP1, SCR2, MGC15146, MGC3331)

Cat. Num. AAA649735

• Gene Names: RBMS1; YC1; MSSP; SCR2; HCC-4; MSSP-1; MSSP-2; MSSP-3; C2orf12
• Reactivity: Human
• Applications: Western Blot
• Purity: Affinity Purified; Purified by Protein A affinity chromatography.
• Synonyms: RBMS1; Polyclonal Antibody; RBMS1 (RNA-binding Motif; Single-stranded-interacting Protein 1; Single-stranded DNA-binding Protein MSSP-1; Suppressor of CDC2 with RNA-binding Motif 2; C2orf12; MSSP; MSSP1; SCR2; MGC15146; MGC3331); Anti -RBMS1 (RNA-binding Motif; anti-RBMS1 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Recognizes human RBMS1.
• Purity/Purification: Affinity Purified; Purified by Protein A affinity chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2.
• Sequence: MGKVWKQQMYPQYATYYYPQYLQAKQSLVPAHPMAPPSPSTTSSNNNSSSSSNSGWDQLSKTNLYIRGLPPHTTDQDLVKLCQPYGKIVSTKAILDKTTNKCKGYGFVDFDSPAAAQKAVSALKASGVQAQMAKQQEQDPTNLYISNLPLSMDEQELENMLKPFGQVISTRILRDSSGTSRGVGFARMESTEKCEAVIGHFNGKFIKTPPGVSAPTEPLLCKFADGGQKKRQNPNKYIPNGRPWHREGEVRLAGMTLTYDPTTAAIQNGFYPSPYSIATNRMITQTSITPYIASPVSAYQVQSPSWMQPQPYILQHPGAVLTPSMEHTMSLQPASMISPLAQQMSHLSLGSTGTYMPATSAMQGAYLPQYAHMQTTAVPVEEASGQQQVAVETSNDHSPYTFQPNK

• Applicable Applications for anti-RBMS1 antibody: Western Blot (WB)
• Application Notes: Suitable for use in Western Blot.
• Immunogen: Full length human RBMS1, aa1-406 (NP_058520.1).
• Preparation and Storage: May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(Western Blot analysis of RBMS1 expression in transfected 293T cell line by RBMS1 polyclonal antibody. Lane 1: RBMS1 transfected lysate (44.5kD). Lane 2: Non-transfected lysate.)

Related Product Information for anti-RBMS1 antibody

This gene encodes a member of a small family of proteins which bind single stranded DNA/RNA. These proteins are characterized by the presence of two sets of ribonucleoprotein consensus sequence (RNP-CS) that contain conserved motifs, RNP1 and RNP2, originally described in RNA binding proteins, and required for DNA binding. These proteins have been implicated in such diverse functions as DNA replication, gene transcription, cell cycle progression and apoptosis. Several transcript variants, resulting from alternative splicing and encoding different isoforms, have been described. A pseudogene for this locus is found on chromosome 12.

Product Categories/Family for anti-RBMS1 antibody

Antibodies; Abs to RNA Binding Proteins

NCBI and Uniprot Product Information

• NCBI GI #: 112180668
• NCBI GeneID: 5937
• UniProt Accession #: P29558; Q14869; Q15433; Q53P46; Q53QX8; Q53RG6; Q8WV20
• Molecular Weight: 44,505 Da
• NCBI Official Full Name: RBMS1 protein
• NCBI Official Synonym Full Names: RNA binding motif, single stranded interacting protein 1
• NCBI Official Symbol: RBMS1
• NCBI Official Synonym Symbols: YC1; MSSP; SCR2; HCC-4; MSSP-1; MSSP-2; MSSP-3; C2orf12
• NCBI Protein Information: RNA-binding motif, single-stranded-interacting protein 1; cervical cancer oncogene 4; c-myc gene single strand binding protein 2; single-stranded DNA-binding protein MSSP-1; suppressor of CDC2 with RNA-binding motif 2; suppressor of cdc 2 (cdc13) with RNA binding motif 2
• UniProt Protein Name: RNA-binding motif, single-stranded-interacting protein 1
• Protein Family: RNA-binding motif, single-stranded-interacting protein
• UniProt Gene Name: RBMS1
• UniProt Synonym Gene Names: C2orf12; MSSP; MSSP1; SCR2
• UniProt Entry Name: RBMS1_HUMAN

NCBI Description

This gene encodes a member of a small family of proteins which bind single stranded DNA/RNA. These proteins are characterized by the presence of two sets of ribonucleoprotein consensus sequence (RNP-CS) that contain conserved motifs, RNP1 and RNP2, originally described in RNA binding proteins, and required for DNA binding. These proteins have been implicated in such diverse functions as DNA replication, gene transcription, cell cycle progression and apoptosis. Several transcript variants, resulting from alternative splicing and encoding different isoforms, have been described. A pseudogene for this locus is found on chromosome 12. [provided by RefSeq, Feb 2009]

Uniprot Description

Function: Single-stranded DNA binding protein that interacts with the region upstream of the MYC gene. Binds specifically to the DNA sequence motif 5'-[AT]CT[AT][AT]T-3'. Probably has a role in DNA replication.

Subcellular location: Nucleus.

Tissue specificity: Highest amounts are found in placenta, lung and heart.

Developmental stage: Expressed at highest levels during the G1 to S transition of the cell cycle.

Sequence similarities: Contains 2 RRM (RNA recognition motif) domains.

Sequence caution: The sequence AAX93095.1 differs from that shown. Reason: Erroneous gene model prediction. The sequence CAA45923.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.The sequence CAA45923.1 differs from that shown. Reason: Frameshift at positions 319 and 360. The sequence CAA54628.1 differs from that shown. Reason: Erroneous translation. Wrong coding sequence.